The Aftermath of COVID-19: Exploring the Long-Term Effects on Organ Systems
Biomedicines,
Journal Year:
2024,
Volume and Issue:
12(4), P. 913 - 913
Published: April 20, 2024
Background:
Post-acute
sequelae
of
SARS-CoV-2
infection
(PASC)
is
a
complicated
disease
that
affects
millions
people
all
over
the
world.
Previous
studies
have
shown
PASC
impacts
10%
infected
patients
which
50–70%
are
hospitalised.
It
has
also
been
10–12%
those
vaccinated
against
COVID-19
were
affected
by
and
its
complications.
The
severity
later
development
symptoms
positively
associated
with
early
intensity
infection.
Results:
generated
health
complications
caused
involve
vast
variety
organ
systems.
Patients
diagnosed
neuropsychiatric
neurological
symptoms.
cardiovascular
system
involved
several
diseases
such
as
myocarditis,
pericarditis,
coronary
artery
reported.
Chronic
hematological
problems
thrombotic
endothelialitis
hypercoagulability
described
conditions
could
increase
risk
clotting
disorders
coagulopathy
in
patients.
Chest
pain,
breathlessness,
cough
respiratory
long-COVID
causing
distress
syndrome.
observed
immune
notable,
involving
diseases.
renal
was
impacted,
resulted
raising
issues,
fibrosis,
sepsis.
Endocrine
gland
malfunction
can
lead
to
diabetes,
thyroiditis,
male
infertility.
Symptoms
diarrhea,
nausea,
loss
appetite,
taste
among
reported
observations
due
gastrointestinal
disorders.
Skin
abnormalities
might
be
an
indication
long-term
implications
persistent
cutaneous
complaints
linked
PASC.
Conclusions:
Long-COVID
multidimensional
syndrome
considerable
public
implications,
affecting
physiological
systems
demanding
thorough
medical
therapy,
more
study
address
underlying
causes
effects
needed.
Language: Английский
Gender differences in sequelae from COVID-19 infection
Trinity Eimer,
No information about this author
Sonia Villapol
No information about this author
Elsevier eBooks,
Journal Year:
2025,
Volume and Issue:
unknown, P. 599 - 613
Published: Jan. 1, 2025
Language: Английский
Assessment of changes in menstrual pattern, menstrual volume, and sex hormones (FSH, LH, TSH, prolactin, and AMH) in women of childbearing age with COVID-19 in Semnan, Iran: a cross-sectional study
Zahra Vafaeinezhad,
No information about this author
Sadra Sarandili,
No information about this author
Safa Mousavi
No information about this author
et al.
Middle East Fertility Society Journal,
Journal Year:
2025,
Volume and Issue:
30(1)
Published: Feb. 28, 2025
Abstract
Introduction
and
objectives
Women’s
reproductive
fertility
health
may
be
influenced
by
COVID-19.
However,
data
on
whether
SARS-CoV-2
infection
affects
menstrual
pattern,
volume,
sex
hormone
levels
remain
limited.
This
study
aimed
to
investigate
changes
in
the
pattern
volume
of
menstruation
as
well
FSH,
LH,
TSH,
prolactin,
AMH
women
age
following
Patients
methods
In
this
cross-sectional
study,
we
enrolled
30
healthy
(aged
18–36
years)
who
presented
with
male-factor
infertility.
Participants
were
included
if
they
non-menopausal,
had
negative
pregnancy
test
results,
no
history
significant
medical
illness
or
drug
treatment.
Women
using
contraceptive
treatments
undergone
specific
therapeutic
procedures
medications
for
infertility
excluded.
Additionally,
vaccinated
against
COVID-19
All
participants
a
confirmed
diagnosis
(positive
PCR
test).
To
minimize
acute-phase
fluctuations,
re-evaluated
5-
7-month
post-infection.
We
compared
pre-
post-infection
from
their
records,
used
screening
checklist
assess
(e.g.,
oligomenorrhea,
polymenorrhea)
volume.
Each
participant
effectively
served
her
own
control.
Data
analyzed
at
95%
confidence
level
P
<
0.05
considered
significant.
Results
The
mean
(±
SD)
was
29.23
±
3.45
years.
Nearly
one-third
(33%)
reported
new-onset
after
COVID-19,
including
oligomenorrhea
(20%)
polymenorrhea
(13%).
No
experienced
amenorrhea.
Post-infection
showed
slight
increase
prolactin
decrease
AMH;
however,
only
TSH
exhibited
statistically
rise.
Changes
not
associated
treatment
methods,
hospitalization,
pulmonary
involvement.
By
contrast,
those
hospitalization
more
frequent
alterations
(
=
0.041
0.006,
respectively).
Pulmonary
involvement
did
significantly
impact
pattern.
Conclusion
linked
increases
notable
shifts
among
age,
while
other
hormones
remained
largely
unchanged.
Further
research
larger
sample
sizes
formal
control
group
is
needed
clarify
these
observations.
Language: Английский
The Aftermath of COVID-19: Exploring Long-Term Effects on the Organ Systems
Published: April 3, 2024
Background:
Post-acute
sequelae
of
SARS-CoV-2
infection
(PASC)
is
a
complicated
disease
that
affects
millions
people
all
over
the
world.
Previous
studies
have
shown
PASC
impacts
10%
infected
patients
which
50-70%
are
hospitalized.
It
has
also
been
10-12%
those
vaccinated
against
COVID-19
were
affected
with
and
its
complications.
The
severity
later
development
symptoms
positively
associated
early
intensity
infection.
Results:
generated
health
complications
caused
by
involve
vast
variety
organ
systems.
Patients
diagnosed
neuropsychiatric
neurological
symptoms.
Cardiovascular
system
involved
several
diseases
such
as
myocarditis,
pericarditis,
coronary
artery
reported.
Chronic
hematological
problems
thrombotic
endothelialitis
hypercoagulability
described
condition
could
increase
risk
clotting
disorders
coagulopathy
in
patients.
Chest
pain,
breathlessness,
cough
respiratory
long
causing
distress
syndrome.
observed
immune
notable,
involving
diseases.
Renal
was
impacted
result
raising
issues,
fibrosis,
sepsis.
Endocrine
gland
malfunction
can
lead
to
diabetes,
thyroiditis,
male
infertility.
Symptoms
diarrhea,
nausea,
loss
appetite
taste
among
reported
observations
due
gastrointestinal
disorders.
Skin
abnormalities
might
be
an
indication
long-term
implications
persistent
cutaneous
complaints
linked
PASC.
Conclusions:
Long
COVID
multidimensional
syndrome
considerable
public
implications,
affecting
physiological
systems
demanding
thorough
medical
therapy
well
more
study
address
underlying
causes
effects.
Language: Английский
Possible mechanisms of SARS-CoV-2-associated myocardial fibrosis: reflections in the post-pandemic era
Zhan Wang,
No information about this author
Luwei Li,
No information about this author
Shuai Yang
No information about this author
et al.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: Oct. 8, 2024
Since
December
2019,
coronavirus
disease
2019
(COVID-19)
has
been
spreading
worldwide
with
devastating
immediate
or
long-term
effects
on
people’s
health.
Although
the
lungs
are
primary
organ
affected
by
COVID-19,
individuals
infected
SARS-CoV-2
also
develop
systemic
lesions
involving
multiple
organs
throughout
body,
such
as
cardiovascular
system.
Emerging
evidence
reveals
that
COVID-19
could
generate
myocardial
fibrosis,
termed
“COVID-19-associated
fibrosis.”
It
can
result
from
activation
of
fibroblasts
via
renin-angiotensin-aldosterone
system
(RAAS),
transforming
growth
factor-β1
(TGF-β1),
microRNAs,
and
other
pathways,
occur
in
cellular
interactions
SARS-CoV-2,
immunocytes,
endothelial
cells.
Nonetheless,
to
gain
a
more
profound
insight
into
natural
progression
COVID-19-related
additional
investigations
necessary.
This
review
delves
underlying
mechanisms
contributing
COVID-19-associated
fibrosis
while
examining
antifibrotic
potential
current
treatments,
thereby
offering
guidance
for
future
clinical
trials
these
medications.
Ultimately,
we
propose
research
directions
post-COVID-19
era,
artificial
intelligence
(AI)
telemedicine.
We
recommend
relevant
tests
be
added
follow-up
patients
detect
promptly.
Language: Английский
The prognostic significance of insulin resistance in COVID-19: a review
Journal of Diabetes & Metabolic Disorders,
Journal Year:
2024,
Volume and Issue:
23(1), P. 305 - 322
Published: Jan. 20, 2024
Language: Английский
Long-Term Impacts of COVID-19 on Thyroid Health: Insights From Clinical Studies
Rajan Syal,
No information about this author
Jasmeet Kaur,
No information about this author
M SIDDIQUI
No information about this author
et al.
Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 14, 2024
COVID-19
emerged
in
December
2019
and
rapidly
became
a
global
pandemic.
It
has
since
been
associated
with
the
progression
of
various
endocrine
disorders,
including
thyroid
disease.
The
long-term
effects
this
interplay
have
yet
to
be
explored.
This
review
explores
relationship
between
diseases,
emphasizing
gland
function
clinical
implications
for
managing
disorders
infected
individuals.
Language: Английский
The Effects of Antipsychotics and Selective Serotonin Reuptake Inhibitors on the Development of Long Covid in a Large Veteran Population
Published: Jan. 1, 2024
Language: Английский
The relation between FT3 and long-term fatigue in patients with COVID-19
Shuo Dong,
No information about this author
FanRui Ding,
No information about this author
Yuan Wang
No information about this author
et al.
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: Aug. 23, 2024
Background
Under
the
current
pandemic
of
Corona
Virus
Disease
2019
(COVID-19),
The
relationship
between
fatigue
and
COVID-19
has
been
found.
Infection
with
is
associated
long
after
acute
phase
COVID-19.
Understanding
association
thyroid
hormones
levels
post-COVID
condition,
such
as
fatigue,
necessary
to
improve
quality
life.
Methods
This
population-based
cohort
study
was
conducted
in
Dalian,
China,
from
December
2022,
March
2023,
using
a
Yidu
Core
platform
First
Affiliated
Hospital
Dalian
Medical
University,
that
integrates
medical
records,
laboratory
tests,
all
diagnosis
treatment
information
based
on
patients
hospital.
Eligible
individuals
were
40
COVID-19,
Divided
them
into
group
non-fatigue
following
up
by
telephone
FS-14
scale
6
months.
primary
outcomes
diagnoses
fatigue.
assessed
logistic
regression
analysis.
Results
Compared
group,
FT
3
level
lower
(
p
<0.05).
negatively
correlated
months
OR
0.257,
After
adjusting
for
confounding
factors
age
gender,
low
risk
factor
0.225,
And
less
than
2.47
mol/L,
it
best
critical
value
predicting
long-term
sensitivity
92.3%
specificity
48.1%.
Conclusions
Most
people
still
have
infection.
serves
important
index
predict
should
be
closely
monitored
during
Language: Английский