Insects, Journal Year: 2024, Volume and Issue: 15(12), P. 916 - 916
Published: Nov. 23, 2024
Seasonal reproductive dynamics and senescence have profound impacts on male fertility, yet these processes remain understudied in scorpions. This study investigates how parameters-such as testicular mass, sperm quantity, viability-change over the course of season
Language: Английский
Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)
Published: Jan. 16, 2024
Abstract Male reproductive traits such as ejaculate size and quality, are expected to decline with advancing age due senescence. It is however unclear whether this expectation upheld across taxa. We perform a meta-analysis on 379 studies, quantify the effects of male 157 species non-human animals. Contrary predictions, we find no consistent pattern age-dependent changes in traits. This result partly reflects methodological limitations, studies sampling low proportion adult lifespan, or inability meta-analytical approaches document non-linear ageing trajectories traits; which could potentially lead an underestimation Yet, taxon-specific differences patterns For instance, older males produce less motile slower sperm ray-finned fishes, but larger ejaculates insects, compared younger males. Notably, lab rodents show senescence most measured. Our study challenges notion universal senescence, highlighting need for controlled methodologies more nuanced understanding cognisant biology, experimental design, selection pressures, life-history.
Language: Английский
Citations
10
Evolution Letters, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 6, 2025
Abstract Male reproductive senescence is typically characterized by a decline in the number of sperm produced and transferred old males, phenomenon that may be exacerbated polygynous species where males mate multiply. However, also transfer seminal fluid to females, little known about its role modulating male senescence. Here, we explore contributions towards series sequential matings, using Drosophila melanogaster. As expected, produce fewer offspring than young males. this pattern not driven limitation: have more similar numbers compared Instead, females storing over long term, drives We are able mitigate age-related output supplementing with male, before she mates an male. Similarly, alleviate reduction across matings fluid. Our findings highlight fluid, rather number, limits success or multiply mating highlighting underappreciated aging.
Language: Английский
Citations
1
Ecological Entomology, Journal Year: 2025, Volume and Issue: unknown
Published: March 12, 2025
Abstract All species exhibit functional senescence, a process related to ageing that is influenced by both abiotic and biotic factors. Ageing leads decline in function drives phenotypic marked reduction performance over time. In temperate regions, overwintering must survive age for several months, often facing challenging conditions with low food availability chilling injuries. Yet, might enter state of dormancy, which can extend longevity enhance stress tolerance. Evaluating the survivors crucial predicting population dynamics, especially significant pests like invasive fruit flies. At end winter, surviving fly populations, are expected rebuild new generations, likely dormant (i.e., reproductive quiescence) senescent. However, their has not been thoroughly described. This study aims decipher effect on tolerance capacity males females summer‐acclimated (SP) versus winter‐acclimated (WP) phenotypes Drosophila suzukii . SP WP flies were reared under normal temperature conditions, respectively, four categories established: very young, middle old. showed typical age‐related fecundity. contrast, cold‐acclimated maintained high exhibited lower but stable potential, despite months at temperature. Our highlights importance distinguishing between summer phenotypes, as differentially affects both.
Language: Английский
Citations
0
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown
Published: April 16, 2025
Abstract In many animals, sperm are stored for extended periods either in the reproductive tracts of males before ejaculation, or females after copulation. Sperm storage reduces risk limitation both sexes and avoids costs female re-mating. However, can lead to post-meiotic senescence, i.e. within-sperm-age-dependent deterioration, potentially impacting conceived offspring lowering male fitness. Yet, extent magnitude such deterioration variables modulating it during not well understood. Using a meta-analysis across humans (115 studies) non-human animals (56 studies from 30 species), we investigate how in-vivo affects quality, fertilisation success, quality. humans, leads greater oxidative stress DNA damage, viability motility. other performance embryo quality decline. We identify duration storage, design used sampling individuals, sex individual storing as important moderators effects storage. These findings have key biomedical implications, including optimising timing ejaculation fertility clinics captive breeding programs. Overall, our results reveal mechanisms that cause fitness consequences provide evolutionary insights into sex-specific adaptations mitigate detrimental
Language: Английский
Citations
0
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown
Published: April 14, 2023
Abstract Senescence, the deterioration of organismal function with advancing age, is a puzzling biological phenomenon. While actuarial senescence ( i.e. , age-dependent increases in mortality rates) well described across some taxa, reproductive age- dependent declines reproduction) less understood, especially males, mixed patterns reported studies. To examine evidence for male senescence, we investigated how age affects ejaculate traits non-human animals via meta-analysis yielding 1814 effect sizes from 379 We found no general pattern senescence. Instead, high heterogeneity reproduction changes animals. Some this (>10%) was associated factors. For example, there were taxonomical differences — sperm motility declined lab rodents and fish, whereas size improved bulls, insects. methodological factors also important explaining heterogeneity: studies sampling larger proportion species’ lifespan more likely to detect traits, emphasising need full life cycle species document Contrary predictions, reveal that sporadic. Our findings will help generate novel hypotheses identify effective approaches studying
Language: Английский
Citations
5
Al- Anbar Medical Journal, Journal Year: 2024, Volume and Issue: 0(0), P. 0 - 0
Published: Jan. 9, 2024
Background: Age can affect seminal fluid parameters (SFPs); many studies reported that SFPs are reduced in older men. Although these alterations may not necessarily cause infertility, they make it harder for men to conceive. Objective: We aimed examine which mostly affected by age among Iraqi population. Material and Methods: A retrospective observational study recruited 120 eligible male participants attending an infertility center, Bagdad, Iraq. The were grouped according their ages into 3 groups as follows: Group I: 21-30 years (41/120); II: 31-40 (43/120), III > 40 (36/120). For each participant, we collected firstly demographic clinical criteria include age, type, its duration, addition abstinence days. Secondly, SFPs, volume, viscosity, liquefaction time, sperm concentration, viability, motility, normal abnormal morphology, round cell count. correlation of with was examined. Results: Analysis showed insignificant differences total viscosity the three groups. I lowest liquefication had highest counts morphology. Abnormal morphology group statistically meaningful across Conclusion: number live immotile, non -progressive, morphological sperms. Since average paternal is rising, imperative educate advancing reduces fertility potential impacts offspring health.
Language: Английский
Citations
1
Evolution, Journal Year: 2024, Volume and Issue: 78(9), P. 1619 - 1632
Published: June 24, 2024
Abstract Advancing male age is often hypothesized to reduce both fertility and offspring quality due reproductive senescence. However, the effects of advancing on output are not always deleterious. For example, older fathers might buffer senescence by terminally investing in reproduction. Similarly, males that survive reproduce at an old carry alleles confer high viability (viability selection), which then inherited offspring, or have potential (selective disappearance). Differentiating these mechanisms requires integrated experimental study paternal survival performance, as well quality, currently lacking. Using a cross-sectional Drosophila melanogaster, we test conception (PAC) success, lifespans sons. We discover mating linked with decreased future survival, suggesting mating-induced mortality possibly being frail. find no evidence for terminal investment show does onset until their late-adult life. Additionally, father’s lifespan increases, his probability siring increases PAC treatments only. Lastly, sons born live longer than those younger selection. Collectively, our results suggest necessarily associated deleterious may even lead producing longer-lived offspring.
Language: Английский
Citations
1
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: July 4, 2024
Abstract Advancing male age can lead to reproductive senescence, which in males is thought be largely driven by declines the numbers of sperm transferred old males. This decline predicted particularly pronounced polygynous species, where become limited over a mating sequence. However, also transfer seminal fluid females, and little known about contribution constrain output old, multiply-mating Using Drosophila melanogaster , we investigated whether age-related variation differential limitation or fluid, series experimental matings. Consistent with produced fewer offspring than young this pattern was not limitation, having more transferring similar female, compared Yet surprisingly, females stored when mated Notably, supplemented suggesting that fertility successive matings availability. Generally, our study indicates germline maintenance might prioritised somatic as hypothesized disposable soma theory ageing, senescence key contributor age. While other factors such viability female post-mating responses could have influenced results, highlights under-appreciated role mediating species. Significance statement A assumption ageing research are less fertile males, reduced partly producing sperm. caused via ejaculate-mediated pathways, investigate using fruit flies. Contrary expectations, reveal because reserves, but instead due changes differences storage These alleviated supplementing “extra” fluid. Our demonstrates reversible, highlighting underappreciated modulating results potential for improving animal understanding sexual selection.
Language: Английский
Citations
1
Journal of Asia-Pacific Entomology, Journal Year: 2024, Volume and Issue: unknown, P. 102365 - 102365
Published: Dec. 1, 2024
Language: Английский
Citations
1
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown
Published: Dec. 21, 2023
Abstract Advancing male age is often hypothesised to reduce both fertility and offspring quality through reproductive senescence. However, the effects of advancing on output need not always be deleterious. For example, older fathers might compensate for senescence by terminally investing in reproduction. Similarly, males that survive reproduce at an old age, carry alleles confer high viability (viability selection) which are then inherited offspring, or have potential (selective disappearance). Differentiating these mechanisms requires integrated experimental study paternal survival performance, as well quality, currently lacking. Using Drosophila melanogaster , we test conception (PAC) success, lifespans sons. We discover mating temporarily linked with decreased future survival, suggesting mating-induced mortality possibly due being frail. also find a quadratic ageing pattern, onset late-life. no evidence terminal investment, instead positive covariances between father’s lifespan his probability siring PAC groups. Lastly, show sons born live longer than those younger fathers, selection. Collectively, our results suggest deleterious can increase fitness if produce more viable offspring. Lay summary It’s assumed fewer lower-quality young fathers. average, usually survived reproduced signals benefit These opposing predictions rarely been tested, it’s unclear what their combined influence is, determining offspring’s fitness. fruit flies, explored how affects reproduction sons’ lifespans. age-related decline who mate subsequently, relationship lifespan, complex previously assumed, provide benefits studies consider. Teaser text Is dad really bad? While some cases worse they thus higher quality. reproducing father son’s senescence, but, surprisingly, lived This effect driven largely themselves living passing conferring Our research important because it reveals specific drive multifaceted
Language: Английский
Citations
1