Knowledge framework and emerging trends of invasive pulmonary fungal infection: A bibliometric analysis (2003–2023) DOI Creative Commons
Ben Liu,

Wenling Dai,

Jie Wei

et al.

Medicine, Journal Year: 2024, Volume and Issue: 103(42), P. e40068 - e40068

Published: Oct. 18, 2024

The rising number of immunocompromised people has increased concerns about fungal infections as a severe public health issue. Invasive pulmonary (IPFIs) are prevalent and often fatal, particularly for those with weakened immune systems. Understanding IPFIs is crucial. work aims to offer concise overview the field’s characteristics, main research areas, development paths, trends. This study searched Web Science Core Collection on June 5, 2024, collecting relevant academic works from 2003 2023. Analysis was conducted using CiteSpace, VOSviewer, Bibliometrix Package in R, Microsoft Excel 2019, Scimago Graphica. indicated that USA, University Manchester, Denning DW led productivity impact, while Journal Fungi topped list terms publication volume citations. High-frequency include “fungal infection,” “invasive,” “diagnosis,” “epidemiology.” Keyword trend analysis identified “influenza,” “COVID-19,” “invasive aspergillosis,” “metagenomic next-generation sequencing” emerging areas. Over last 2 decades, IPFI surged, topics becoming more profound. These insights key guidance current trends, gaps, trajectory studies.

Language: Английский

Redox Homeostasis, Gut Microbiota, and Epigenetics in Neurodegenerative Diseases: A Systematic Review DOI Creative Commons
Constantin Munteanu, Anca‐Irina Galaction, Marius Turnea

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(9), P. 1062 - 1062

Published: Aug. 30, 2024

Neurodegenerative diseases encompass a spectrum of disorders marked by the progressive degeneration structure and function nervous system. These conditions, including Parkinson's disease (PD), Alzheimer's (AD), Huntington's (HD), Amyotrophic lateral sclerosis (ALS), Multiple (MS), often lead to severe cognitive motor deficits. A critical component neurodegenerative pathologies is imbalance between pro-oxidant antioxidant mechanisms, culminating in oxidative stress. The brain's high oxygen consumption lipid-rich environment make it particularly vulnerable damage. Pro-oxidants such as reactive nitrogen species (RNS) (ROS) are continuously generated during normal metabolism, counteracted enzymatic non-enzymatic defenses. In diseases, this balance disrupted, leading neuronal This systematic review explores roles stress, gut microbiota, epigenetic modifications aiming elucidate interplay these factors identify potential therapeutic strategies. We conducted comprehensive search articles published 2024 across major databases, focusing on studies examining relationships redox homeostasis, changes neurodegeneration. total 161 were included, comprising clinical trials, observational studies, experimental research. Our findings reveal that stress plays central role pathogenesis with microbiota composition significantly influencing balance. Specific bacterial taxa markers identified modulators suggesting novel avenues for intervention. Moreover, recent evidence from human animal supports emerging concept targeting homeostasis through therapies. Future research should focus validating targets settings exploring personalized medicine strategies based individual profiles.

Language: Английский

Citations

5
Microbioma humano y epigenética: nuevas fronteras en la salud personalizada DOI Creative Commons

Blanca Elena Unaucho Quishpe,

Rosa Natividad Tacuri Chunata,

Norma Lucia Alvarado Grefa

et al.

South Florida Journal of Development, Journal Year: 2025, Volume and Issue: 6(2), P. e5007 - e5007

Published: Feb. 24, 2025

En esta investigación se presenta la relación entre el microbioma humano y epigenética, enfocándose en su importancia salud personalizada presencia varias patologías como las crónicas, metabólicas, autoinmunes neurodegenerativas. A partir de revisión estudios recientes, analizan interacciones los microbiomas, tales intestinales piel, alteraciones epigenéticas que afectan procesos fundamentales, regulación del sistema inmunológico, metabólico progreso cognitivo. El objetivo es investigar cómo alteración microbiomas mediante alimentación, probióticos, ejercicio físico varios métodos terapéuticos sofisticados puede influir marcas epigenéticas, ofreciendo posibilidades para intervenciones particulares basándose características individuales. Se toman cuenta casos efecto microbiota primeros 1,000 días vida, conexión eje microbioma-cerebro durante envejecimiento resistencia a antimicrobianos metabólicas. Este método combina instrumentos análisis multiómico tecnologías actuales un entendimiento más detallado biológicas. Por último, artículo propone marco interdisciplinario reinterpreta medicina actual, indicando profundo vínculo con epigenética transformar prevención tratamiento enfermedades desde una perspectiva personalizada.

Citations

0
Research Status and Trends of Gut Microbiota and Intestinal Diseases Based on Bibliometrics DOI Creative Commons
Xiao Sun, Jiancheng Zhai

Microorganisms, Journal Year: 2025, Volume and Issue: 13(3), P. 673 - 673

Published: March 17, 2025

Gut microbiota plays an important role in gut health, and its dysbiosis is closely related to the pathogenesis of various intestinal diseases. The field diseases has not yet been systematically quantified through bibliometric methods. This study conducted analysis delineate evolution research on Data were sourced from Web Science Core Collection database 2009 2023 scientometrically analyzed using CiteSpace. We have found that number annual publications steadily increasing showing upward trend. China Chinese Academy Sciences are country institution with most contributions, respectively. Frontiers Microbiology Nutrients journals publications, while Plos One Nature citations. shifted focusing traditional descriptive composition exploring causal relationship between hotspots trends mainly include correlation specific diversity, mechanism involvement diseases, exploration human health. provides a comprehensive knowledge map highlights key areas, outlines potential future directions.

Language: Английский

Citations

0
Global research trends and hotspots in rheumatoid arthritis joint replacement:Bibliometric analysis and visualization study DOI Creative Commons
Lin Zeng, Yihan Shi,

Parhati Subatijang

et al.

Journal of Orthopaedics, Journal Year: 2024, Volume and Issue: 61, P. 72 - 84

Published: Sept. 29, 2024

Language: Английский

Citations

1
Dysbiosis–epigenetics–immune system interaction and ageing health problems DOI
Sima Ataollahi Eshkoor,

Sara Fanijavadi

Journal of Medical Microbiology, Journal Year: 2024, Volume and Issue: 73(11)

Published: Nov. 28, 2024

An erratum of this article has been published full details can be found at 10.1099/jmm.0.001961 Background. The growing interest in microbiota–epigenetics–immune system research stems from the understanding that microbiota, a group micro-organisms colonized human body, influence gene expression through epigenetic mechanisms and interaction with immune system. Epigenetics refers to changes activity are not caused by alteration DNA sequence itself. Discussion. clinical significance lies potential develop new therapies for diseases linked imbalance these microbial species (dysbiosis), such as cancer neurodegenerative diseases. intricate between microbiota epigenetics involves production metabolites signalling molecules impact our health influencing responses, metabolism inflammation. Understanding interactions could lead novel therapeutic strategies targeting microbiota–epigenetic pathways improve outcomes. Conclusion. In context, we aim review emphasize current knowledge key concepts link function, exploring their relevance development maintenance homeostasis susceptibility different later life. We elucidate concerning effects among gut epigenetics, ageing dysbiosis.

Language: Английский

Citations

1
Global research progress of nanomedicine and colorectal cancer: a bibliometrics and visualization analysis DOI Creative Commons
Siyu Tian, Min Chen

Frontiers in Oncology, Journal Year: 2024, Volume and Issue: 14

Published: Dec. 6, 2024

Surgery and chemoradiotherapy are the main clinical treatment methods for colorectal cancer (CRC), but prognosis is poor. The emergence of nanomedicine brings bright light to CRC. However, there has not been a comprehensive systematic analysis CRC by bibliometrics.

Language: Английский

Citations

1
Bibliometric analysis of global research trends between gut microbiota and breast cancer: from 2013 to 2023 DOI Creative Commons
Xianguang Deng,

Hua Yang,

Lingjia Tian

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: July 31, 2024

Background Breast cancer is the most prevalent globally and associated with significant mortality. Recent research has provided crucial insights into role of gut microbiota in onset progression breast cancer, confirming its impact on disease’s management. Despite numerous studies exploring this relationship, there a lack comprehensive bibliometric analyses to outline field’s current state emerging trends. This study aims fill that gap by analyzing key directions identifying hotspots. Method Publications from 2013 2023 were retrieved Web Science Core Collection database. The VOSviewer, R language SCImago Graphica software utilized analyze visualize volume publications, countries/regions, institutions, authors, keywords field. Results A total 515 publications included study. journal Cancers was identified as prolific, contributing 21 papers. United States China leading contributors University Alabama at Birmingham productive institution. Peter Bai published papers, while James J. Goedert cited author. Analysis highly literature keyword clustering confirmed close relationship between cancer. Keywords such “metabolomics” “probiotics” have been prominently highlighted analysis, indicating future hotspots interaction metabolites microenvironment microbiota. Additionally, these suggest interest therapeutic potential probiotics for treatment. Conclusion Research expanding. Attention should be focused understanding mechanisms their interaction, particularly metabolite-microbiota-breast crosstalk. These advance prevention, diagnosis, treatment strategies provides assessment trends field, offering valuable perspectives

Language: Английский

Citations

0
Probiotics, Prebiotics, Fecal Microbiota Transplantation, and Dietary Patterns in Inflammatory Bowel Disease DOI

Noah Noguera‐Fernández,

Joana Candela‐González,

Esteban Orenes‐Piñero

et al.

Molecular Nutrition & Food Research, Journal Year: 2024, Volume and Issue: 68(18)

Published: Aug. 28, 2024

Scope Inflammatory bowel disease (IBD) is one of the most common chronic and debilitating functional disorders affecting around 11% population across world. IBD associated with 3.6 million physician visits per year, being reason visiting a gastroenterologist second to be absent from work, sharply increasing health care costs. Methods Results Several treatments seem effective in symptoms relief, such as probiotics, prebiotics, fecal microbiota transplantation (FMT), dietary patterns. Probiotics (living microorganisms that can supplemented) protect against pathogenic bacteria due their antimicrobial qualities. Prebiotics (nondigestible food ingredients) promote growth beneficial microbial strains gut, giving benefit host. FMT supposed directly change recipient's composition when transfer gastrointestinal healthy donor carried out. And finally, patterns are spotlight, presence certain nutrients tract motility, sensitivity, barrier function, gut microbiota. Conclusion It particularly important know what treatment options available which efficient relieving improving patient's quality life.

Language: Английский

Citations

0
Knowledge framework and emerging trends of invasive pulmonary fungal infection: A bibliometric analysis (2003–2023) DOI Creative Commons
Ben Liu,

Wenling Dai,

Jie Wei

et al.

Medicine, Journal Year: 2024, Volume and Issue: 103(42), P. e40068 - e40068

Published: Oct. 18, 2024

The rising number of immunocompromised people has increased concerns about fungal infections as a severe public health issue. Invasive pulmonary (IPFIs) are prevalent and often fatal, particularly for those with weakened immune systems. Understanding IPFIs is crucial. work aims to offer concise overview the field’s characteristics, main research areas, development paths, trends. This study searched Web Science Core Collection on June 5, 2024, collecting relevant academic works from 2003 2023. Analysis was conducted using CiteSpace, VOSviewer, Bibliometrix Package in R, Microsoft Excel 2019, Scimago Graphica. indicated that USA, University Manchester, Denning DW led productivity impact, while Journal Fungi topped list terms publication volume citations. High-frequency include “fungal infection,” “invasive,” “diagnosis,” “epidemiology.” Keyword trend analysis identified “influenza,” “COVID-19,” “invasive aspergillosis,” “metagenomic next-generation sequencing” emerging areas. Over last 2 decades, IPFI surged, topics becoming more profound. These insights key guidance current trends, gaps, trajectory studies.

Language: Английский

Citations

0