Anti-biofilm effect of clove oil against Candida albicans: A systematic review DOI

J Palaskar Sangeeta,

O Balsaraf Aishwarya,

D Balsaraf Omkar

et al.

Journal of Oral and Maxillofacial Pathology, Journal Year: 2024, Volume and Issue: 28(4), P. 665 - 671

Published: Oct. 1, 2024

In recent years, Candida albicans has emerged as a significant opportunistic pathogen, causing various infections, particularly in immunocompromised geriatric individuals. One of the major hindrances managing infections lies its potential to develop and survive biofilms, which demonstrate resistance conventional antifungal therapies, thereby complicating treatment strategies. While clove oil shown promising results agent, specific anti-biofilm effects against biofilms remain relatively underexplored. Therefore, there is need for comprehensive review evaluate existing literature on properties mechanisms action biofilms. Such will provide valuable insights into therapeutic applications combating biofilm-associated infections. This enable us infer understand albicans. systematic aims determine efficacy was registered 'PROSPERO' (CRD42024524134) followed Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines. The searches used Google Scholar, PubMed, Science Direct databases. All original studies published English from 2004 2023 were included. From 37 found online, only four reviewed. Results showed that had activity when assessed Our provides oil's agent Clove also represents avenue future research development

Language: Английский

Development of photodynamic therapy in treating oral diseases DOI Creative Commons
Ling Wang, Qiang Chen, Dan Liu

et al.

Frontiers in Oral Health, Journal Year: 2025, Volume and Issue: 5

Published: Jan. 15, 2025

The morbidity of oral disorders, including gingivitis, caries, endodontic-periodontal diseases, and cancer, is relatively high globally. Pathogenic cells are the root cause many therapies depend on eradicating them. Photodynamic therapy (PDT) has been established as a potential non-invasive local adjuvant treatment for disorders. PDT consists three essential components: photosensitizer (PS), light source with certain wavelength, oxygen dissolved in cells. These components can interact to damage proteins, lipids, nucleic acids, other biological within diseased tissues. Herein, we aimed provide detailed understanding how it treat diseases. Concerns about remedies also factor. shown numerous clinical studies be an efficient supplementary that reduce pathogenic great dental applications, treating bacterial fungal infections during canal preventing potentially malignant periodontitis, peri-implant Although promoted having significant utility dentistry, more research must conducted before being used broadly.

Language: Английский

Citations

1
The effect of photobiomodulation on oral microbiota dysbiosis: A literature review DOI Creative Commons
Maryam Pourhajibagher, Fateme Gharibpour, Nariman Nikparto

et al.

Photodiagnosis and Photodynamic Therapy, Journal Year: 2025, Volume and Issue: unknown, P. 104525 - 104525

Published: Feb. 1, 2025

Language: Английский

Citations

1
Photoinactivation of Enterococcus faecalis Biofilm: In Vitro Antimicrobial Effect of Photoexcited Rutin-Gallium(III) Complex via Visible Blue Light DOI
Maryam Pourhajibagher,

Hassan-Ali Ghafari,

Rashin Bahrami

et al.

Journal of Endodontics, Journal Year: 2024, Volume and Issue: 50(5), P. 602 - 611

Published: Jan. 23, 2024

Language: Английский

Citations

4
Nanoarchitectonics-Based Materials as a Promising Strategy in the Treatment of Endodontic Infections DOI Creative Commons

Suli Xiao,

Guanwen Sun,

Shan Huang

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(6), P. 759 - 759

Published: June 4, 2024

Endodontic infections arise from the interactive activities of microbial communities colonizing in intricate root canal system. The present study aims to update latest knowledge nanomaterials, their antimicrobial mechanisms, and applications endodontics. A detailed literature review current nanomaterials used endodontic was performed using PubMed database. Antimicrobial with a small size, large specific surface area, high chemical activity are introduced act as irrigants, photosensitizer delivery systems, medicaments, or modify sealers. application field could enhance efficiency, increase dentin tubule penetration, improve treatment outcomes. This supports potential promising strategy treating infections.

Language: Английский

Citations

4
Photodynamic black phosphorus nanosheets functionalized with polymyxin B for targeted ablation of drug-resistant mixed-species biofilms DOI

Jie Yu,

Chen‐Hui Li, Weipeng Zhang

et al.

Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 372, P. 795 - 809

Published: July 5, 2024

Language: Английский

Citations

4
Clinical and microbiological efficiencies of indocyanine green-mediated photodynamic therapy and Laser curettage as adjunct to nonsurgical periodontal therapy for treatment of stage 3 periodontitis: a randomized clinical trial DOI

Zahraa Abid,

Nada K. Imran, Manaf Taher Agha

et al.

Lasers in Dental Science, Journal Year: 2025, Volume and Issue: 9(1)

Published: Feb. 19, 2025

Language: Английский

Citations

0
Understanding the Role of Bacterial Biofilm in Antibiotic Resistance: Defensive Strategies and Clinical Challenges DOI Creative Commons

Syed Hamza Abbas,

Hafiza Sehrish Kiani,

F GOHAR

et al.

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Bacterial biofilms significantly cause persistent exacerbation of infections in the clinical setting. These groups microorganisms are highly resistant to host immune responses and conventional antibiotic therapies, whereas they embedded an extracellular matrix. This chapter provides more detailed information on mechanism biofilm formation involving key stages adherence, maturation, spread, including composition structure a further explores how contribute resistance, physical barriers drug penetration, quorum sensing mechanisms, adaptive resistance strategies such as genetic adaptation, stress responses, persister cells. The role horizontal gene transfer spread within communities is also discussed. discusses challenges posed by biofilm-associated infections, focusing diagnosing treating chronic recurrent factors persistence, limitations current therapeutic options. Finally, we address emerging countermeasures counter mediated biofilms, enzymatic nanomedicine technologies, natural product-based inhibitors, inhibitory agents, photodynamic sonodynamic antimicrobial therapy, combinatorial therapies.

Language: Английский

Citations

0
Construction and Characterization of Polyethylene Glycol/Sodium Alginate Hydrogel Loaded With Zirconia Nanoparticles: Potential Antibacterial and Antibiofilm Agent to Inhibit Dental Caries In Vitro and In Vivo DOI Creative Commons

Layth L. Hamid,

Roqaya S. Zakir,

Nur indah noviyanti Rahman

et al.

Microscopy Research and Technique, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Biofilm formation on tooth surfaces is a primary contributor to dental caries and periodontal diseases. Streptococcus mutans recognized for its role in biofilm production, significantly influencing the development of caries. Key virulence factors associated with S. biofilms include acid tolerance, synthesis exopolysaccharides (EPS). This study presents novel approach by focusing loading biosynthesized zirconia nanoparticles (ZrO2 NPs) onto polyethylene glycol/sodium alginate (PEG/SA) hydrogel nanocomposite, evaluating their effects biofilm-forming ability both vivo vitro. ZrO2 NPs were using Citrus aurantifolia (C. aurantifolia) extract incorporated into PEG/SA beads through sol-gel process. The PEG/SA/ZrO2 nanocomposite was confirmed diverse analyzes, including UV-visible spectroscopy, particle size measurement, morphology examination, spectral analysis, thermal gravimetric analysis (TGA) hemolysis studies. average approximately 26 nm, while exhibited highly porous, sheet-like surface structure. In vitro results demonstrated inhibition zones 30 28 mm against mutans, respectively, minimum inhibitory concentration (MIC) 12.5 mg/mL. growth curve indicated complete decline an 87% reduction when treated beads. SEM revealed that cells appeared lysed or crumpled, losing characteristic coccal shape after exposure Additionally, images effective prevention attachment teeth encapsulated hydrogel, altering mature developed treatment. Finally, incorporation hydrogels demonstrates significant potential as strategy inhibiting may serve promising topical agent reducing Further studies could explore long-term efficacy clinical applications this oral health care.

Language: Английский

Citations

0
Evaluating the potency of laser-activated antimicrobial photodynamic therapy utilizing methylene blue as a treatment approach for chronic periodontitis DOI Creative Commons

Manoj Kumar Karuppan Perumal,

Remya Rajan Renuka,

Prabhu Manickam Natarajan

et al.

Frontiers in Oral Health, Journal Year: 2024, Volume and Issue: 5

Published: May 30, 2024

Chronic periodontitis is a ubiquitous inflammatory disease in dental healthcare that challenging to treat due its impact on bone and tooth loss. Conventional mechanical debridement has been eliminating complex subgingival biofilms. Hence, adjunctive approaches like low-level laser antimicrobial photodynamic therapy (A-PDT) utilising methylene blue (MB) have emerging recent times. This review evaluates the latest research use of MB-mediated A-PDT decrease microbial count enhance clinical results chronic periodontitis. Studies shown interaction between light MB generates phototoxic effect thereby, pathogenic bacteria within periodontal pockets. Moreover, numerous trials using can reduce probing depths, improve attachment levels, bleeding during comparison traditional treatment approaches. Notably, shows superior antibiotic resistance compared conventional treatments. In conclusion, promise as an for Additional required standardize protocols assess long-term outcomes with

Language: Английский

Citations

3
In vitro effect of photodynamic therapy with two photosensitizers on Streptococcus mutans load around metal and ceramic brackets bonded to enamel DOI Creative Commons

Narjes Karamad,

Fatemeh Fazel,

Shima Afrasiabi

et al.

Photodiagnosis and Photodynamic Therapy, Journal Year: 2025, Volume and Issue: unknown, P. 104547 - 104547

Published: March 1, 2025

The inherent surface porosities of ceramic brackets can enhance bacterial plaque accumulation. This study assessed the in-vitro effect photodynamic therapy (PDT) with two photosensitizers (PSs) on Streptococcus mutans (S. mutans) load around metal and bonded to enamel. In this in vitro experimental study, 48 sound premolars extracted for orthodontic reasons were randomly assigned groups (n=24) bonding brackets. After bracket bonding, tooth-bracket assemblies inoculated S. mutans, each group was divided into three subgroups (n=8) control, PDT toluidine blue O (TBO) 635 nm laser, indocyanine green (ICG) 808 laser. colony count quantified subgroup, analyzed by repeated measures ANOVA. Ceramic showed a significantly higher than control subgroup 7.057 log10 CFUs/mL (P<0.05). PDT, irrespective PS type, decreased both (by 7.616 ICG 7.594 TBO subgroup) 7.512 7.505 difference not significant between after (P=0.541 P=0.101 TBO). Within limitations as an attempt predict what might happen vivo, results that enamel, type PS. Thus, may be considered possibly efficient strategy minimize especially

Language: Английский

Citations

0