Long COVID in Children, Adults, and Vulnerable Populations: A Comprehensive Overview for an Integrated Approach

Diseases, Journal Year: 2024, Volume and Issue: 12(5), P. 95 - 95

Published: May 6, 2024

Long COVID affects both children and adults, including subjects who experienced severe, mild, or even asymptomatic SARS-CoV-2 infection. We have provided a comprehensive overview of the incidence, clinical characteristics, risk factors, outcomes persistent COVID-19 symptoms in encompassing vulnerable populations, such as pregnant women oncological patients. Our objective is to emphasize critical significance adopting an integrated approach for early detection appropriate management long COVID. The incidence severity can significant impact on quality life patients course disease case pre-existing pathologies. Particularly, fragile patients, presence PASC related significantly worse survival, independent from vulnerabilities treatment. It important try achieve recognition management. Various mechanisms are implicated, resulting wide range presentations. Understanding specific factors involved crucial tailoring effective interventions support strategies. Management approaches involve biopsychosocial assessments treatment comorbidities, autonomic dysfunction, well multidisciplinary rehabilitation. overall one gradual improvement, with recovery observed majority, though not all, As research long-COVID continues evolve, ongoing studies likely shed more light intricate relationship between chronic diseases, status, cardiovascular psychiatric disorders, effects This information could guide healthcare providers, researchers, policymakers developing targeted interventions.

Language: Английский

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COVID-19 Pediatric Follow-Up: Respiratory Long COVID-Associated Comorbidities and Lung Ultrasound Alterations in a Cohort of Italian Children

Children, Journal Year: 2024, Volume and Issue: 11(2), P. 166 - 166

Published: Jan. 27, 2024

In children, the factors that influence COVID-19 disease and its medium- long-term effects are little known. Our investigation sought to evaluate presence of comorbidity associated with respiratory long COVID manifestations in children study ultrasound abnormalities following SARS-CoV-2 infection. Children, who arrived at ‘Respiratory Diseases Pediatric Interest Unit’ Department Woman, Child, General Specialized Surgery University Campania ‘Luigi Vanvitelli’, were selected during timeframe from September 2021 October 2022. The diagnosed a infection occurred least one month before visit. All patients followed follow-up protocol, developed by Italian Society Respiratory (SIMRI), which included: collection data regarding illness history known allergic diseases; physical examination; BMI assessment; baseline spirometry after bronchodilation test; six-minute walking lung (LUS). cohort 104 participants symptoms (64.7% male, average age 8.92 years), 46.1% had fever other symptoms, 1% required hospitalization. analysis showed 58.4% was overweight. LUS positive 27.0% cases. A significant association observed score (p-value < 0.05). No associations found asthma or atopy.

Language: Английский

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Understanding Experiences of Youth with Long COVID: A Qualitative Approach

Children, Journal Year: 2024, Volume and Issue: 11(3), P. 335 - 335

Published: March 12, 2024

There is limited information on the specific impacts of Long COVID in youth. presents as persisting or new symptoms following initial COVID-19 infection. The aim this study was to better understand how children and their families describe experiences seeking diagnosis support onset COVID. Six five caregivers located United States participated study. Study procedures included an online video interview with caregiver–child dyads. Interview transcriptions were then analyzed using a conventional approach content analysis, two independent coders generating themes. Eight themes emerged from analysis including severity illness symptomatology, difficulty surrounding diagnostic process not being believed, impact family social connections, poor school functioning, positive coping, subsequent medical experiences, mental health, knowledge field healthcare experience. Themes revealed for youth navigating system functioning areas daily life well related coping involvement. These findings also highlighted needed improvement community research

Language: Английский

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Long COVID in pediatric age: an observational, prospective, longitudinal, multicenter study in Italy

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: April 9, 2025

This observational prospective longitudinal multicenter study examines the occurrence and characteristics of long COVID (LC) in Italian pediatric population. Conducted across 12 Pediatric Units Italy from January to March 2022, involved 1129 children diagnosed with SARS-CoV-2 infection. Data were collected via self-administered questionnaires at 1-3 months, 3-6 6-12 months post-infection, LC defined as symptoms persisting for least 2 occurring 3 post-diagnosis. Results revealed that 68.6% reported one post-COVID symptom, 16.2% experiencing LC. The most frequent included respiratory issues (43.4%), neurological cognitive dysfunction (27.7%), gastrointestinal (22.1%), fatigue (21.6%), sleep disturbances (18.8%). Age gender differences significant, older females more prone cardiovascular & dysfunction. highlights presents similarly adults, though less frequently. was lower compared adult populations, likely due generally milder course COVID-19 children. findings underscore need targeted follow-up support affected children, especially considering long-term persistence symptoms. Further research is necessary explore impact vaccines on effects different variants. These insights are crucial developing strategies manage mitigate impacts recovering COVID-19.

Language: Английский

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Exploring Long COVID in Pediatric Patients: Clinical Insights from a Long COVID Clinic

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 26, 2024

Background: Long COVID or post-acute sequelae of SARS-CoV-2 infection is a persistent condition following acute infection, affecting both adults and children. However, studies exploring the clinical spectrum impact vaccination on long in children remain limited. Methods: We conducted retrospective chart review data analysis aged 0-21 years who were seen at clinic Children’s Hospital Los Angeles between August 2021 November 2023. All statistical analyses performed using R Studio 4.2.2. Results: The study included 123 patients with mean age 13.1 years, whom 63 (51.2%) males. onset symptoms occurred 5 weeks after an average symptom duration 31.3 presentation. Notably, 23 (18.6%) experienced lasting over 12 months. most commonly reported fatigue (92.7%), headache (69.9%), exercise intolerance (52.8%), dizziness (43.9%), brain fog (40.7%). Among 74 least one follow-up visit, general decrease severity was observed time. No significant difference found number 6 months vaccinated unvaccinated groups. Of 43 COVID, 19 (44.2%) improvement. Conclusion: Fatigue are prevalent pediatric across various A reduction burden time, appears to have beneficial effect alleviating some Larger extended follow-ups necessary further validate these findings.

Language: Английский

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The effect of COVID-19 vaccination on symptomatic infection and related symptoms among preterm-born children aged 3–7 years in China

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 25, 2024

Vaccination plays a crucial role in preventing and controlling SARS-CoV-2 infections as well their associated adverse outcomes. But there is notable lack of research on the effectiveness COVID-19 vaccination children, particularly those young preterm-born who are more vulnerable to severe outcomes from infection. We aimed determine effect with inactivated vaccines BBIBP-CorV CoronaVac symptomatic infection related symptoms children aged 3-7 years after relaxation prevention control measures December 2022 China. performed retrospective cohort study involving 242 data were collected March 2023. Logistic regression models modified Poisson combined entropy balancing used explore associations against COVID-19, specific symptoms, persistent one month recovery COVID-19. Of recruited 156 (64.5%) vaccinated CoronaVac. After balancing, covariates balanced between unvaccinated groups, standardized mean difference < 0.001. said lowered risk developing (risk ratio [RR] = 0.783; 95% confidence interval [CI]: (0.711, 0.861). Likewise, was decline pneumonia (odds [OR] 0.318; CI 0.110, 0.913), fever (RR 0.710; 0.635, 0.794), high 0.542; 0.297, 0.988), sore throat (OR 0.304; 0.139, 0.664), 0.425; 0.182, 0.993). Immunization provides protection for years.

Language: Английский

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Perspective Chapter: Sequelae and Consequences of COVID-19 in the Paediatric Population

IntechOpen eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 25, 2024

During the pandemic and in subsequent years, we observed that COVID-19 caused by SARS-CoV-2 virus affected paediatric population different ways. In certain groups of children adolescents, social isolation, changes family dynamics, increased exposure to technological screens diet, among others, have their development, education, emotional, physical aspects, including access immunizations, medical surveillance control. is considered a generally benign pathology children; however, some patients develop well-defined post-COVID-19 entities: multisystem inflammatory syndrome (MIS-C) long COVID. this chapter, review, relation population, effects confinement during its development consequences, forms clinical presentation entities MIS-C COVID, prevalence, pathophysiology, presentation, evolution, detection management recommendations.

Language: Английский

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Diagnostic challenges of long COVID in children: a survey of pediatric health care providers’ preferences and practices

Frontiers in Pediatrics, Journal Year: 2024, Volume and Issue: 12

Published: Dec. 23, 2024

Given the challenges in diagnosing children with long COVID, we sought to explore diagnostic practices and preferences among clinicians. A ten-question survey assessed pediatric providers' clinical decision making for identifying evaluating COVID children. Of 120 respondents, 84 (70%) were physicians, 31 (26%) nurse practitioners, 5 (4%) physician assistants. The most common categories of symptoms identified as raising suspicion included cardiopulmonary symptoms, selected by 119 (99%) providers, neurocognitive 118 (98%) providers. However, there was more ambiguity on primary feature providers selecting a range key symptoms. all physical exam findings, postural orthostatic tachycardia, suggestive [identified 49 (41%) providers], whereas one-third reported no specific identifiable finding. Pediatric report variable evaluation patient demographics factors impacting whether diagnosis is considered. This variation reflects definition absence guidelines support identification disease treatment. study highlights an area need future advances COVID.

Language: Английский

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