Microbial synthesis of titanium dioxide nanoparticles and their importance in wastewater treatment and antimicrobial activities: a review

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Oct. 16, 2023

Nanotechnology (NT) and nanoparticles (NPs) have left a huge impact on every field of science today, but they shown tremendous importance in the fields cosmetics environmental cleanup. NPs with photocatalytic effects positive responses wastewater treatment, cosmetics, biomedical field. The chemically synthesized TiO2 (TiO2 NPs) utilize hazardous chemicals to obtain desired-shaped TiO2. So, microbial-based synthesis has gained popularity due its eco-friendly nature, biocompatibility, etc. Being NPs, high surface area-to-volume ratio addition their degradation nature. In present review, authors emphasized microbial (algae, bacterial, fungi, virus-mediated) NPs. Furthermore, exhibited food sector, automobile, aerospace, medical,

Language: Английский

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Breaking Barriers in Eco-Friendly Synthesis of Plant-Mediated Metal/Metal Oxide/Bimetallic Nanoparticles: Antibacterial, Anticancer, Mechanism Elucidation, and Versatile Utilizations

Journal of Nanomaterials, Journal Year: 2024, Volume and Issue: 2024, P. 1 - 48

Published: April 12, 2024

Nanotechnology has emerged as a promising field in pharmaceutical research, involving producing unique nanoscale materials with sizes up to 100 nm via physiochemical and biological approaches. Nowadays more emphasis been given eco-friendly techniques for developing nanomaterials enhance their applications minimize health environmental risks. With the help of green nanotechnology, wide range metal, metal oxide, bimetallic nanoparticles distinct chemical compositions, sizes, morphologies have manufactured which are safe, economical, environment friendly. Due biocompatibility vast potential biomedical (antibacterial, anticancer, antiviral, analgesic, anticoagulant, biofilm inhibitory activity) other fields such (nanofertilizers, fermentative, food, bioethanol production, construction field), garnered significant interest worldwide. The precursors combined natural extracts plants, algae, fungi, bacteria get potent novel Ag, Au, Co, Cu, Fe, Zr, Zn, Ni, Pt, Mg, Ti, Pd, Cd, Bi2O3, CeO2, Co3O4, CoFe2O4, CuO, Fe2O3, MgO, NiO, TiO2, ZnO, ZrO2, Ag-Au, Ag-Cr, Ag-Cu, Ag-Zn, Ag-CeO2, Ag-CuO, Ag-SeO2, Ag-TiO2, Ag-ZnO, Cu-Ag, Cu-Mg, Cu-Ni, Pd-Pt, Pt-Ag, ZnO-CuO, ZnO-SeO, ZnO-Se, Se-Zr, Co-Bi2O3. These plant-mediated possess excellent antibacterial anticancer activity when tested against several microorganisms cancer cell lines. Plants contain essential phytoconstituents (polyphenols, flavonoids, terpenoids, glycosides, alkaloids, etc.) compared sources (bacteria, algae) higher concentration that play vital role development because these plant-phytoconstituents act reducing, stabilizing, capping agent helps nanoparticles. After concluding all findings, this review designed first time way it imparts satisfactory knowledge about together, along mechanisms. Additionally, provides information characterization (UV–vis, FT-IR, DLS, XRD, SEM, TEM, BET, AFM) employed nanoparticles, applications, industries. Hence, various types versatile application diverse is not covered pieces literature.

Language: Английский

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Advancements in Metal and Metal Oxide Nanoparticles for Targeted Cancer Therapy and Imaging: Mechanisms, Applications, and Safety Concerns

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106622 - 106622

Published: Jan. 1, 2025

Language: Английский

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Green Synthesis of Copper Nanoparticles Using Panchagavya: Nanomaterials for Antibacterial, Anticancer, and Environmental Applications

Luminescence, Journal Year: 2025, Volume and Issue: 40(2)

Published: Feb. 1, 2025

ABSTRACT This study explores the green synthesis of copper nanoparticles (Cu‐NPs) using Panchagavya, a traditional organic substance composed five cow‐derived components, as reducing and stabilizing agent. Cu‐NPs were characterized UV–Vis, FT‐IR, XRD, SEM‐EDS, TEM, DLS, zeta potential analysis, which revealed their size, shape, elemental properties. They exhibited strong antibacterial activity against Bacillus cereus Pseudomonas aeruginosa . Biofilm inhibition was observed at various concentrations, with 38.98% ½ MIC, 67.48% 84.03% 2× MIC. SEM analysis confirmed that disrupted bacterial cell membrane, causing leakage cellular contents. Antioxidant assays (DPPH, FRAP) high scavenging activity, percentages 88.50% 92.54%, respectively. showed anticancer on MCF7 cells, an IC 50 38.18 μg/mL. Additionally, significantly reduced nitric oxide (NO) production in RAW 264.7 macrophage cells dose‐dependent manner. The also larvicidal efficacy, 99.12% mortality Aedes aegypti 95.26% Culex quinquefasciatus , LC values 29.40 μg/mL 93.55 μg/mL, Morphological changes treated larvae included body shrinkage degeneration tracheal tube ventral brush noticed compared to control. Histopathological examinations Cu‐NP‐treated several structural damages, including damage gut epithelial dissipation muscle layer, loss goblet cells. GC–MS Panchagavya its for biological applications. These findings highlight eco‐friendly multifunctional nature Panchagavya‐mediated Cu‐NPs, demonstrating antimicrobial, antioxidant, anticancer, applications, could contribute sustainable pest disease management strategies.

Language: Английский

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Sea buckthorn, its bioactive constituents, and mechanism of action: potential application in female reproduction

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 7, 2023

Sea buckthorn ( Hippophae rhamnoides L.) is a flowering shrub, and its berries have been utilized for decades as raw ingredient in cuisines herbal remedies. This evidence-based study focuses on key bioactive constituents, mechanism of protective effects with focus female reproductive processes. Parts the plant contain phenols, carotenoids (lycopene, carotene, lutein, zeaxanthin), flavonoids (isorhamnetin, quercetin, glycosides, kaempferol), tocopherols, sterols, polyunsaturated fatty acids, minerals, vitamins, omega 3, 6, 9 rare 7 acids etc. Key polyphenolic such isorhamnetin quercetin are believed to be mainly responsible behind health benefits (against cardiovascular diseases, metabolic syndrome, obesity etc.) through properties including anti-cancer, antioxidant, anti-inflammatory activities. These sea constituents appear mediate healthy ovarian cell proliferation, death, hormone release, well decrease cancer possibly apoptosis, hormonal (estrogen) release. Thus, ingredients may potential management gynecological problems uterine inflammation, endometriosis, easing symptoms vulvovaginal atrophy postmenopausal women (by targeting inflammatory cytokines vascular endothelial growth factor – VEGF). Apigenin, myricetin, luteolin also recommended prospective preventative adjuvant therapy options they can inhibit cancerogenesis by triggering apoptosis halting cycle tumors. Furthermore, oil (containing carotenoid, sterol, hypericin) has speculated an alternative estrogen replacement particularly improve vaginal epithelial integrity. However, it uncertain whether steroid receptors, reactive oxygen species (ROS), regulators actually buckhorn’s actions. buckthorn, compounds’ promoting warrants further validation not just vitro animal research, but clinical trials identify and/or standardize optimal methods delivery biologically active molecules.

Language: Английский

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Synthesis of Lawsonia inermis-encased silver–copper bimetallic nanoparticles with antioxidant, antibacterial, and cytotoxic activity

Green Processing and Synthesis, Journal Year: 2024, Volume and Issue: 13(1)

Published: Jan. 1, 2024

Abstract The extract of the medicinal plant Lawsonia inermis , known as henna, was employed to synthesize silver–copper bimetallic nanoparticles (Ag–Cu NPs) in a unique, efficient, and cost-effective method. shape, size, structural features synthesized Ag–Cu NPs were determined by ultra–visible spectroscopy, Fourier transform infrared X-ray diffractometer, field emission scanning electron microscopy, transmission energy dispersive spectroscopy methods. rod-shaped nanoparticles, averaging 41.66 ± 17.18 nm from L. exhibited potent antioxidant activity inhibiting 2,2-diphenyl-1-picrylhydrazyl 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) free radicals. They also displayed significant antibacterial effects against Pseudomonas aeruginosa (28 mm), Staphylococcus aureus (27 Bacillus cereus (26 Escherichia coli (24 mm). Additionally, these induced notable morphological changes cancer cells demonstrated promising cytotoxicity MDA-MB-231 tumor (IC 50 = 37.40 µg·mL −1 ). However, they biotoxicity Artemia nauplii resulting mortality rates ranging 3.0% 32.5%. LC 90 values recorded for 48-h exposure 1.51 mg·L 2.59 respectively. These findings highlight potential application -derived pharmacology bio-nanomedicine.

Language: Английский

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A comparative anticancer analysis of Iron Oxide nanoparticles of Hippophae rhamnoides and Cichorium intybus found in the Karakoram Range of Gilgit Baltistan against liver cancer targeting the RhoA gene

Drug Development and Industrial Pharmacy, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 10

Published: Sept. 3, 2024

The current research work focused on the evaluation of

Language: Английский

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Eco-friendly Nanoparticle Synthesis for Cancer Treatment: A Sustainable Healthcare Approach

Published: Jan. 1, 2025

Language: Английский

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Composition of Flavonoids and Nutritional Evaluation in Leaves of Different Sea‐Buckthorn Germplasm Resources

Food Science & Nutrition, Journal Year: 2025, Volume and Issue: 13(4)

Published: April 1, 2025

ABSTRACT Sea‐buckthorn leaves contain various active components, and research, development, utilization of sea‐buckthorn have broad application prospects in the fields food, medicine, feed. The comprehensive quality different germplasm resources was evaluated by determining 17 major nutrients, such as flavone composition, polysaccharides, total flavonoids, polyphenols, so on 26 varieties sea buckthorn leaves, then factor analysis, principal component cluster analysis. results showed that flavonols, mainly quercetin‐like flavonols isorhamnetin‐like were detected sea‐buckthorns. Through analysis its nutritional quality, it found had highly significant genetic differences diversity, polyphenol content, polysaccharide VC flavonoids crude fat content comparable to those some commercially available high‐quality famous teas. higher protein ‘ S1 ’, fiber S4 ’ S13 ’. S8 relatively S22 S5 S18 S7 suggest a certain extent these lines seem serve botanical resource for extraction protein, fiber, fat, polysaccharide, respectively. contents S21 S24 high, polyphenols suggesting buckthorns could be used plant extracting from extent. Factor S3 S16 S10 highest ranking. this study laid good foundation screening breeding, processing, new leaves.

Language: Английский

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Phytonanofabrication of Copper Oxide from Albizia saman and Its Potential as an Antimicrobial Agent and Remediation of Congo Red Dye from Wastewater

Water, Journal Year: 2023, Volume and Issue: 15(21), P. 3787 - 3787

Published: Oct. 29, 2023

Metal nanoparticle fabrication through plant-based green methods is considered the gold standard among various synthesis techniques owing to its simplicity, eco-friendliness, ease of use, and huge diversity plant species. Copper nanoparticles (CuONPs) have proven their potential in fields medicine, agriculture, pharmaceutics, catalysis, are being synthesized using physicochemical biological methods. Here, authors reported on first-ever use Albizia saman leaf extract for development CuONPs. Phytochemical analysis methanolic extracts exhibited presence phenols (32.31%), tannins (12.27%), flavonoids (16.72%). The phytonutrients existing successfully reduced copper salt A detailed investigation CuONPs was performed advanced instruments. UV-Vis spectra an absorbance peak at 290 nm, while X-ray diffraction pattern (XRD) revealed that average crystallite size about 29.86 nm. Dynamic light scattering (DLS) hydrodynamic 72.3 nm diameter, zeta −0.49, with a negative polarity. Fourier transform infrared spectroscopy showed major bands region 400 1000 cm−1, suggesting formation CuONPs, band 1100 2600 cm−1 shows association molecules phytonanofabricated CuO particles. Transmission scanning electron microscopy spherical shape whose 20–50 antibacterial activity by forming zone inhibition (ZOI) against Escherichia coli, Staphylococcus aureus, Candida albicans. removal efficiency 33.33% Congo Red dye. CR dye 16% after 4th cycle.

Language: Английский

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