Chemical Papers, Journal Year: 2024, Volume and Issue: 78(6), P. 3443 - 3462
Published: Feb. 17, 2024
Language: Английский
Chemical Papers, Journal Year: 2024, Volume and Issue: 78(6), P. 3443 - 3462
Published: Feb. 17, 2024
Language: Английский
Journal of Hazardous Materials Advances, Journal Year: 2024, Volume and Issue: unknown, P. 100478 - 100478
Published: Sept. 1, 2024
Language: Английский
Citations
3Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 116921 - 116921
Published: May 1, 2025
Language: Английский
Citations
0International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: unknown, P. 125105 - 125105
Published: Dec. 1, 2024
Language: Английский
Citations
3Frontiers in Toxicology, Journal Year: 2024, Volume and Issue: 6
Published: July 1, 2024
With the expansion of nanomaterials (NMs) usage, concerns about their toxicity are increasing, and wide variety NMs makes it difficult to assess toxicity. Therefore, development a high-throughput, accurate, certified method evaluate immunotoxicity is required. In this study, we assessed potential various NMs, such as nanoparticles silver, silica, titanium dioxide, using human Cell Line Activation Test (h-CLAT) at cellular level. After exposure silver nanoparticle dispersions, expression levels CD86 CD54 increased, suggesting activation antigen-presenting cells (APCs) by nanoparticles. Quantification ions eluted from APCs suggested that was due release ions. Silica also increased and/or CD54, ability correlated with synthesis methods hydrodynamic diameters. The dioxide activate differed depending on crystal type diameter. These results suggest based monocytic THP-1 cells. This will be valuable in assessing elucidating immunotoxic mechanisms NMs.
Language: Английский
Citations
2Chemical Papers, Journal Year: 2024, Volume and Issue: 78(6), P. 3443 - 3462
Published: Feb. 17, 2024
Language: Английский
Citations
1