Binocular processing facilitates escape behavior through multiple pathways to the superior colliculus DOI Creative Commons
Robin Broersen,

Genevieve Thompson,

F Thomas

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 22, 2024

Summary The superior colliculus (SC) is the main brain region regulating innate defensive behaviors to visual threat. Yet, how SC integrates binocular information and what extent vision drives unknown. Here, we show that facilitates visually-evoked escape behavior. Furthermore, find neurons respond input with diverse synaptic spiking responses, summate inputs largely sublinearly. Using pathway-specific optogenetic silencing contralateral ipsilateral carried through retinal, interhemispheric corticotectal pathways. These pathways carry in a layer-specific manner, superficial layers receiving retinal input, whereas intermediate deep rely on Together, our data shed light cellular circuit mechanisms underlying processing its role

Language: Английский

Genetically defined neuron types underlying visuomotor transformation in the superior colliculus DOI
Jianhua Cang, Chen Chen,

Chuiwen Li

et al.

Nature reviews. Neuroscience, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 27, 2024

Language: Английский

Citations

6
Binocular processing facilitates escape behavior through multiple pathways to the superior colliculus DOI
Robin Broersen,

Genevieve Thompson,

F Thomas

et al.

Current Biology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Binocular processing facilitates escape behavior through multiple pathways to the superior colliculus DOI Creative Commons
Robin Broersen,

Genevieve Thompson,

F Thomas

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 22, 2024

Summary The superior colliculus (SC) is the main brain region regulating innate defensive behaviors to visual threat. Yet, how SC integrates binocular information and what extent vision drives unknown. Here, we show that facilitates visually-evoked escape behavior. Furthermore, find neurons respond input with diverse synaptic spiking responses, summate inputs largely sublinearly. Using pathway-specific optogenetic silencing contralateral ipsilateral carried through retinal, interhemispheric corticotectal pathways. These pathways carry in a layer-specific manner, superficial layers receiving retinal input, whereas intermediate deep rely on Together, our data shed light cellular circuit mechanisms underlying processing its role

Language: Английский

Citations

0