Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
17(1)
Published: Jan. 1, 2025
ABSTRACT
The
clinical
availability
of
photon‐counting
computed
tomography
(PCCT)
has
ushered
in
a
new
era
CT
imaging.
Spectral
imaging
coupled
with
superior
contrast
resolution,
and
ultrahigh
spatial
resolution
(200
μm)
offered
by
PCCT
the
potential
to
revolutionize
value‐driven
multicolor
generated
excitement,
renewed
interest,
novel
agent
development
for
comprehensive
disease
interrogation,
prediction
monitoring
treatment
outcomes.
Nanoparticles
provide
versatile
powerful
platform
next
generation
agents
spectral
PCCT.
In
this
article,
we
review
recent
developments
use
nanoparticle
We
also
discuss
future
research
translational
opportunities
nanoparticle‐based
enabled
advent
describe
key
considerations
their
translation.
Journal of Functional Biomaterials,
Journal Year:
2025,
Volume and Issue:
16(1), P. 24 - 24
Published: Jan. 14, 2025
Autoimmune
diseases
present
complex
therapeutic
challenges
due
to
their
chronic
nature,
systemic
impact,
and
requirement
for
precise
immunomodulation
avoid
adverse
side
effects.
Recent
advancements
in
biodegradable
stimuli-responsive
nanomaterials
have
opened
new
avenues
targeted
drug
delivery
systems
capable
of
addressing
these
challenges.
This
review
provides
a
comprehensive
analysis
state-of-the-art
nanocarriers
such
as
polymeric
nanoparticles,
liposomes,
hydrogels
engineered
autoimmune
therapies.
These
are
designed
degrade
safely
the
body
while
releasing
agents
response
specific
stimuli,
including
pH,
temperature,
redox
conditions,
enzymatic
activity.
By
achieving
localized
controlled
release
anti-inflammatory
immunosuppressive
agents,
minimize
toxicity
enhance
efficacy.
We
discuss
underlying
mechanisms
nanomaterials,
recent
applications
treating
rheumatoid
arthritis,
multiple
sclerosis,
inflammatory
bowel
disease,
design
considerations
essential
clinical
translation.
Additionally,
we
address
current
challenges,
biocompatibility,
scalability,
regulatory
hurdles,
well
future
directions
integrating
advanced
nanotechnology
with
personalized
medicine
treatment.
highlights
transformative
potential
presenting
them
promising
strategy
advance
precision
improve
patient
outcomes
disease
management.
Heliyon,
Journal Year:
2025,
Volume and Issue:
11(4), P. e42739 - e42739
Published: Feb. 1, 2025
This
review
explores
the
synergistic
potential
of
natural
products
and
nanotechnology
for
viral
infections,
highlighting
key
antiviral,
immunomodulatory,
antioxidant
properties
to
combat
pandemics
caused
by
highly
infectious
viruses.
These
often
result
in
severe
public
health
crises,
particularly
affecting
vulnerable
populations
due
respiratory
complications
increased
mortality
rates.
A
cytokine
storm
is
initiated
when
an
overload
pro-inflammatory
cytokines
chemokines
released,
leading
a
systemic
inflammatory
response.
Viral
mutations
limited
availability
effective
drugs,
vaccines,
therapies
contribute
continuous
transmission
virus.
The
coronavirus
disease-19
(COVID-19)
pandemic
has
sparked
renewed
interest
product-derived
antivirals.
efficacy
traditional
medicines
against
infections
examined.
Their
anti-inflammatory,
are
highlighted.
discusses
how
enhances
herbal
combating
infections.
Cancers,
Journal Year:
2025,
Volume and Issue:
17(2), P. 198 - 198
Published: Jan. 9, 2025
Mathematical
models
are
crucial
for
predicting
the
behavior
of
drug
conjugate
nanoparticles
and
optimizing
delivery
systems
in
cancer
therapy.
These
simulate
interactions
among
nanoparticle
properties,
tumor
characteristics,
physiological
conditions,
including
resistance
targeting
specificity.
However,
they
often
rely
on
assumptions
that
may
not
accurately
reflect
vivo
conditions.
In
vitro
studies,
while
useful,
fully
capture
complexities
environment,
leading
to
an
overestimation
nanoparticle-based
therapy
effectiveness.
Advancements
mathematical
modeling,
supported
by
preclinical
data
artificial
intelligence,
vital
refining
therapies
improving
their
translation
into
effective
clinical
treatments.
BIO Integration,
Journal Year:
2025,
Volume and Issue:
6(1)
Published: Jan. 1, 2025
Lipid-based
Nanoparticles
(LBNPs)
have
emerged
as
a
transformative
approach
in
cancer
treatment,
offering
innovative
drug
delivery
solutions
that
enhance
therapeutic
efficacy
while
minimizing
adverse
effects.
By
exploring
the
characterization,
classification,
synthesis,
targeting
strategies,
and
advantages
of
LBNPs,
this
study
highlights
how
LBNPs
been
used
to
overcome
limitations
traditional
chemotherapy
improve
patient
outcomes.
As
nanotechnology
revolutionizes
therapy,
emergence
promising
strategy
for
targeted
has
led
optimism
regarding
future
treatment.
This
review
extensively
assesses
structure,
categories,
production
methods,
benefits,
recent
advancements
treating
cancer.
It
also
current
challenges
possible
directions.
is
aimed
at
providing
comprehensive
understanding
LBNPs’
potential
therapy.
Liposomes,
nanostructured
lipid
carriers,
solid
nanoparticles,
lipid-polymer
hybrid
nanoparticles
are
all
types
each
with
unique
features
interest
These
particles
can
be
synthesized
through
various
procedures,
such
bulk
nanoprecipitation,
solvent-based
emulsification,
or
microfluidics.
Passive
systems,
active
responsive
platforms
direct
tumors.
Consequently,
provide
an
improved
release
pattern
minimizes
side
effects
enhancing
efficacy.
With
combination
offer
hopeful
Continued
research
expected
outcomes
overall
quality
life
care.
