Psychology of sport and exercise, Journal Year: 2025, Volume and Issue: unknown, P. 102823 - 102823
Published: Feb. 1, 2025
Language: Английский
Ageing Research Reviews, Journal Year: 2023, Volume and Issue: 86, P. 101868 - 101868
Published: Feb. 2, 2023
Language: Английский
Citations
80
International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(21), P. 13348 - 13348
Published: Nov. 1, 2022
Chronic stress, even stress of a moderate intensity related to daily life, is widely acknowledged be predisposing or precipitating factor in neuropsychiatric diseases. There clear relationship between disturbances induced by stressful stimuli, especially long-lasting and cognitive deficits rodent models affective disorders. Regular physical activity has positive effect on the central nervous system (CNS) functions, contributes an improvement mood abilities (including memory learning), correlated with increase expression neurotrophic factors markers synaptic plasticity as well reduction inflammatory factors. Studies published so far show that energy challenge caused exercise can affect CNS improving cellular bioenergetics, stimulating processes responsible for removal damaged organelles molecules, attenuating inflammation processes. brings another important benefit: increased robustness. The evidence from animal studies sedentary lifestyle associated vulnerability, whereas physically active resilience. Here, we have performed comprehensive PubMed Search Strategy accomplishing exhaustive literature review. In this review, discuss findings experimental molecular neurobiological mechanisms underlying impact brain A thorough understanding neuroprotective potential preconditioning role resilience, among other things, may open further options prevention therapy treatment
Language: Английский
Citations
46
Frontiers in Neuroscience, Journal Year: 2023, Volume and Issue: 17
Published: Aug. 8, 2023
Concurrent with recent insights into the neuroprogressive nature of depression, ketamine shows promise in interfering several factors, and has been suggested to reverse neuropathological patterns seen depression. These come at a time great need for novel approaches, as prevalence is rising current treatment options remain inadequate large number people. The rapidly growing literature on ketamine's antidepressant potential yielded multiple proposed mechanisms action, many which have implications recently elucidated aspects depressive pathology. This review aims provide reader an understanding pathology how act it. Literature was identified through PubMed Google Scholar, reference lists retrieved articles. When reviewing evidence pathology, picture emerges four elements interacting each other facilitate progressive worsening, namely stress, inflammation, neurotoxicity neurodegeneration. Ketamine acts all these levels rapid potent reductions symptoms. Converging suggests that works increase stress resilience stress-induced dysfunction, modulate systemic inflammation neuroinflammation, attenuate neurotoxic processes glial synaptogenesis rather than Still, much remains be revealed about research lacking durability effect. findings discussed herein calls more longitudinal approaches when determining efficacy its relation could relevant considerations clinical implementation.
Language: Английский
Citations
39
PeerJ, Journal Year: 2024, Volume and Issue: 12, P. e17059 - e17059
Published: Feb. 29, 2024
Background Resilience is vital for improving mental health and well-being during adolescence, which an important yet vulnerable period. Previous research has indicated that physical activity enhances individual resilience. However, limited studies have examined underlying psychological mechanisms between them. The current study aimed to investigate the effect of on adolescent resilience via self-efficacy basic needs. Methods A cross-sectional survey was conducted with 1,732 high school students aged 16 20 years old (mean age: 16.51 ± 0.77 years), nearly equal number boys (47.63%) girls (52.37%). They each completed Physical Exercise Questionnaire, Basic Psychological Needs in Scale, General Self-Efficacy respectively. serial indirect model constructed examine how influences Results Structural equation analysis revealed significantly directly predicted When needs were included model, both direct effects observed. Specifically, positive relationship partially mediated by In addition, found serially mediate relathonship Conclusions present provides novel theoretical insights into sports psychology establishing a link self-efficacy. findings implications administrators education instructors designing targeted interventions promote These may involve creating supportive environment conductive fulfilling students’ needs, implementing strategies enhance beliefs, providing opportunities skill development mastery experiences activities.
Language: Английский
Citations
9
Diagnostics, Journal Year: 2025, Volume and Issue: 15(3), P. 351 - 351
Published: Feb. 3, 2025
Background/Objectives: The purpose of this study has been to evaluate the effects a dance-based aerobic training program on frailty, cognitive impairment, executive functions, and verbal fluency in older adults with mild impairment. Methods: Randomized clinical trial, whose sample was made up 92 adults, which 47 performed rhythmic physical activity for 12 weeks. Data frailty were collected through FRAIL, function Mini-Mental State Examination (MMSE), impairment Montreal Cognitive Assessment (MoCA), using Isaac test, functions Trail Making Test (TMT). All variables measured before after intervention by an independent researcher blinded treatment. Results: Participants experimental group showed statistically significant improvements (Cohen’s d = 0.60), 0.98), 1.22), 0.61) 0.64). Conclusions: This demonstrated that 12-week can significantly reduce improve abilities These suggest is not only effective terms health, but also promoting mental health general well-being.
Language: Английский
Citations
1
International Journal of Environmental Research and Public Health, Journal Year: 2021, Volume and Issue: 18(7), P. 3722 - 3722
Published: April 2, 2021
Considering the significance of resilience in coping with adversity, how to improve college students' is worthy attention. Previous studies have revealed that physical activity can promote resilience; however, few examined mediating factors between them. The purpose this study was investigate effect on resilience, as well effects competence need, autonomy and relatedness need resilience. involved 2375 students (1110 males 1265 females), an average age 20.25 years (
Language: Английский
Citations
54
Open Heart, Journal Year: 2022, Volume and Issue: 9(2), P. e002171 - e002171
Published: Dec. 1, 2022
The deacetylase sirtuin 1 (Sirt1), activated by calorie restriction and fasting, exerts several complementary effects on cellular function that are favourable to healthspan; it is often thought of as an ‘anti-aging’ enzyme. Practical measures which might boost Sirt1 activity therefore considerable interest. A number nutraceuticals have potential in this regard. Nutraceuticals reported enhance synthesis or protein expression include ferulic acid, tetrahydrocurcumin, urolithin A, melatonin, astaxanthin, carnosic acid neochlorogenic acid. half-life can be enhanced with the natural nicotinamide catabolite N1-methylnicotinamide. availability Sirt1’s obligate substrate NAD+ increased ways: riboside mononucleotide substrates for synthesis; activators AMP-activated kinase—such berberine—can increase phosphoribosyltransferase, rate limiting nutraceutical quinones such thymoquinone pyrroloquinoline quinone promoting oxidation NADH. Induced ketosis—as via ingestion medium-chain triglycerides—can brain lessening reduction mediated glycolysis. Post-translational modifications O-GlcNAcylation sulfonation its activity, suggesting administration glucosamine agents hydrogen sulfide may aid activity. Although resveratrol has poor pharmacokinetics, bind activate allosterically—as so-called sirtuin-activating compound drugs. Since oxidative stress reduce multiple ways, effective antioxidant supplementation blunts also help preserve some circumstances. Combination regimens providing physiologically meaningful doses these agents, capable activating health promotion. Such amplify benefits sodium-glucose cotransporter-2 (SGLT2) inhibitors non-diabetic disorders, appear reflect upregulation kinase activities.
Language: Английский
Citations
35
Advances in Clinical and Experimental Medicine, Journal Year: 2023, Volume and Issue: 32(9), P. 937 - 942
Published: Sept. 4, 2023
Physical activity (PA) significantly influences emotional wellbeing, from enhancing mood to counteracting disorders such as depression and anxiety. This article offers an in-depth analysis of the neurobiological processes theories underpinning benefits PA which arise exercise-induced physiological changes that simultaneously benefit brain function. We discuss role growth factors, neurotransmitters biochemicals, well enhancements in mitochondrial biogenesis antioxidant activity, how they foster exercise performance health. Central our discussion are related depression: "neurotrophic," "neurogenesis," "inflammation," "oxidative stress," "monoamine" hypotheses. also introduce emergent "glutamate hypothesis" lactate release a potential precursor for glutamate. Additionally, we explore "endorphin" "endocannabinoid" hypotheses, underscoring their implications evoking feelings euphoria, pain relief diminished anxiety after exercise. In conclusion, exerts diverse influence on health wellbeing. The dynamic interplay between signals promising avenue future research, with innovative therapeutic strategies disorders.
Language: Английский
Citations
20
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(21), P. 11602 - 11602
Published: Oct. 29, 2024
This narrative review examines the relationship between dopamine-related genetic polymorphisms, personality traits, and athletic success. Advances in sports genetics have identified specific single nucleotide polymorphisms (SNPs) genes linked to traits crucial for performance, such as motivation, cognitive function, emotional resilience. clarifies how variations can influence predisposition through dopaminergic pathways environmental interactions. Key findings reveal associations SNPs enhanced performance various sports. For example, COMT Val158Met rs4680 BDNF Val66Met rs6265 are associated with that could benefit increased focus, stress resilience conscientiousness, especially martial arts. DRD3 rs167771 is higher agreeableness, benefiting teamwork like football. synthesis underscores multidimensional role of shaping ability advocates integrating profiling into personalized training optimize well-being. However, research gaps remain, including need standardized protocols exploring gene–environment interactions diverse populations. Future studies should focus on epigenetic factors inform tailored interventions enhance both physical psychological aspects performance. By bridging genetics, psychology, exercise science, this paves way innovative optimization strategies.
Language: Английский
Citations
8
International Journal of Molecular Sciences, Journal Year: 2021, Volume and Issue: 22(14), P. 7339 - 7339
Published: July 8, 2021
Newborn neurons in the adult hippocampus are regulated by many intrinsic and extrinsic cues. It is well accepted that elevated glucocorticoid levels lead to downregulation of neurogenesis, which this review discusses as one reason why psychiatric diseases, such major depression, develop after long-term stress exposure. In reverse, neurogenesis has been suggested protect against stress-induced hence, could serve a resilience mechanism. review, we will summarize current knowledge about functional relation health disease. A special focus lie on mechanisms underlying cascades events from prolonged high concentrations reduced numbers newborn neurons. addition neurotransmitter neurotrophic factor dysregulation, these include immunomodulatory pathways, microbiota changes influencing gut-brain axis. Finally, discuss recent findings delineating role resilience.
Language: Английский
Citations
38