Ceramics International, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Ceramics International, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Psychoneuroendocrinology, Journal Year: 2024, Volume and Issue: 166, P. 107065 - 107065
Published: April 29, 2024
Language: Английский
Citations
3Toxicology in Vitro, Journal Year: 2024, Volume and Issue: 99, P. 105870 - 105870
Published: June 6, 2024
Particulate matter 2.5 (PM
Citations
3Molecular Nutrition & Food Research, Journal Year: 2023, Volume and Issue: 67(17)
Published: July 14, 2023
Scope Excessive iron contributes to oxidative damage and cognitive decline in Alzheimer's disease. Sesamol, a compound sesame oil that exhibits both anti‐inflammatory neuroprotective properties, is examined this study for its ability alleviate impairments overload mice model. Methods results An model established by intraperitoneally injecting dextran (250 mg kg −1 body weight) twice week 6 weeks, while sesamol (100 administered daily the same length of time. The demonstrate protects spatial working memory learning mice, inhibits neuronal loss brain atrophy induced overload. Moreover, significantly decreases interleukin‐6 malondialdehyde, increases glutathione peroxidase 4 brains mice. Additionally, maintains homeostasis regulating expressions transferrin receptors, divalent metal transporter 1, hepcidin, reducing accumulation. Furthermore, suppresses disturbed systemic inflammation, particularly liver expression. Conclusion These findings suggest may be effective mitigating neuroinflammatory responses overload, potentially through involvement mediating liver‐brain axis.
Language: Английский
Citations
7Food & Function, Journal Year: 2024, Volume and Issue: 15(18), P. 9070 - 9084
Published: Jan. 1, 2024
PERK/CHOP pathway-mediated excessive endoplasmic reticulum (ER) stress is closely linked to aging-related cognitive impairment (ARCD). Zerumbone (ZB), a naturally occurring sesquiterpene molecule obtained from dietary bitter ginger, has garnered significant interest due its diverse range of biological properties. It unclear, though, if ZB can reduce ARCD by preventing ER that dependent on the pathway. Here, PERK-CHOP pathway was main focus an evaluation effects and mechanisms for attenuating in D-galactose (D-gal)-induced aging mice SH-SY5Y cells. According our findings, not only greatly decreased neuronal both
Language: Английский
Citations
2Ceramics International, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Citations
2