Two conserved vocal central pattern generators broadly tuned for fast and slow rates generate species-specific vocalizations inXenopusclawed frogs DOI Creative Commons
Ayako Yamaguchi,

Manon Peltier

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 28, 2023

ABSTRACT Across phyla, species-specific vocalizations are used by males to attract females. Functional analyses of the neural circuitry underlying behavior have been difficult, particularly in vertebrates. However, using an ex vivo brain preparation that produces fictive vocalizations, we previously identified anatomically distinct fast and slow central pattern generators (CPGs) drive clicks male courtship calls African clawed frogs, Xenopus laevis . To gain insight into evolution circuits calls, extended this approach four additional species. Here, show although exact rate duration unique each species, CPGs X. conserved across Further, development depends on testosterone a manner: facilitates species with call containing clicks, but not made entirely clicks. Finally, showed that, unlike other vestigial remain latent, inherited all species; rather, they possessed only produce The results suggest genus evolved utilizing or broadly tuned generate trains which appear be regulated strategic expression receptors

Language: Английский

Fundamental challenges and likely refutations of the five basic premises of the polyvagal theory DOI Creative Commons
Paul Grossman

Biological Psychology, Journal Year: 2023, Volume and Issue: 180, P. 108589 - 108589

Published: May 1, 2023

The polyvagal collection of hypotheses is based upon five essential premises, as stated by its author (Porges, 2011). Polyvagal conjectures rest on a primary assumption that brainstem ventral and dorsal vagal regions in mammals each have their own unique mediating effects control heart rate. link these putative dorsal- vs. ventral-vagal differences to socioemotional behavior (e.g. defensive immobilization, social affiliative behaviors, respectively), well trends the evolution vagus nerve Porges, 2011 & 2021a). Additionally, it note only one measurable phenomenon—as index processes—serves linchpin for virtually every premise. That phenomenon respiratory sinus arrhythmia (RSA), heart-rate changes coordinated phase respiration (i.e. inspiration expiration), often employed an vagally, or parasympathetically, mediated assume RSA mammalian phenomenon, since Porges (2011) states "RSA has not been observed reptiles." I will here briefly document how basic premises shown be either untenable highly implausible available scientific literature. also argue reliance equivalent general tone even cardiac conceptually category mistake (Ryle, 1949), confusing approximate RSA) (some process) with itself.

Language: Английский

Citations

23
The neurobiology of vocal communication in marmosets DOI Creative Commons
Dori M. Grijseels,

Brendan Prendergast,

Julia C. Gorman

et al.

Annals of the New York Academy of Sciences, Journal Year: 2023, Volume and Issue: 1528(1), P. 13 - 28

Published: Aug. 24, 2023

Abstract An increasingly popular animal model for studying the neural basis of social behavior, cognition, and communication is common marmoset ( Callithrix jacchus ). Interest in this New World primate across neuroscience now being driven by their proclivity prosociality repertoire, high volubility, rapid development, as well amenability to naturalistic testing paradigms freely moving recording imaging technologies. The complement these characteristics set marmosets up be a powerful brain years come. Here, we focus on vocal because it area that has both made most progress illustrates prodigious potential species. We review current state field with various areas networks involved perception production, comparing findings from other animals, including humans.

Language: Английский

Citations

15
Context-dependent activation of a social behavior brain network during learned vocal production DOI
Katherine L. Anderson,

Lionel Colón,

Violet Doolittle

et al.

Brain Structure and Function, Journal Year: 2023, Volume and Issue: 228(7), P. 1785 - 1797

Published: Aug. 24, 2023

Language: Английский

Citations

5
Evolution of air‐borne vocalization: Insights from neural studies in the archeobatrachian species Bombina orientalis DOI Creative Commons
Stefan Huggenberger, W. Walkowiak

The Journal of Comparative Neurology, Journal Year: 2024, Volume and Issue: 532(3)

Published: March 1, 2024

Abstract Vocalization of tetrapods evolved as an air‐driven mechanism. Thus, it is conceivable that the underlaying neural network might have from more ancient respiratory circuits and be made up homologous components generate breathing rhythms across vertebrates. In this context, extant species stem anurans provide opportunity to analyze connection lung ventilation vocalization. Here, we analyzed fictive vocalization behavior isolated brains Chinese fire‐bellied toad Bombina orientalis during their mating season by nerve root recordings. We discovered significant differences in durations activation male after stimulation statoacoustic or vocalization‐relevant forebrain structures comparison female brains. The increased motor activities can interpreted calling, male's advertisement calls vivo had same general pattern compared ventilation, but longer duration periods. Female react corresponding stimulations with shorter activity occurred spontaneously both thus ventilations. These results support hypothesis vocal respiration networks anuran caudal hindbrain. Moreover, could show terrestrial archeobatrachian spec . appropriate model study function evolution shared generation.

Language: Английский

Citations

0
Courtship behavior: Resurrecting an undead song DOI
Darcy B. Kelley

Current Biology, Journal Year: 2024, Volume and Issue: 34(13), P. R623 - R625

Published: July 1, 2024

Language: Английский

Citations

0
“Neural correlates of social signaling in rodents: An acoustic perspective” DOI Creative Commons
Dori M. Grijseels, Alena Lemazina, Luciana López‐Jury

et al.

Current Opinion in Neurobiology, Journal Year: 2024, Volume and Issue: 89, P. 102927 - 102927

Published: Oct. 18, 2024

Language: Английский

Citations

0
Afferent and Efferent Connections of the Postinspiratory Complex (PiCo) Revealed by AAV and Monosynaptic Rabies Viral Tracing DOI
Luíz M. Oliveira, Alyssa Huff, Aguan Wei

et al.

The Journal of Comparative Neurology, Journal Year: 2024, Volume and Issue: 532(11)

Published: Nov. 1, 2024

ABSTRACT The control of the respiratory rhythm and airway motor activity is essential for life. Accumulating evidence indicates that postinspiratory complex (PiCo) crucial generating behaviors occur during phase, including expiratory laryngeal swallowing. Located in ventromedial medulla, PiCo defined by neurons co‐expressing two neurotransmitter markers (ChAT Vglut2/Slc17a6). Here, we mapped input–output connections these using viral tracers intersectional viral‐genetic tools. were specifically targeted focal injection a doubly conditional Cre‐ FlpO‐dependent AAV8 marker (AAV8‐Con/Fon‐TVA‐mCherry) into left adult Chat Cre/wt : Vglut2 FlpO/wt mice, anterograde axonal tracing. These experiments revealed projections to various brain regions, Cu, nucleus solitary tract (NTS), Amb, X, XII, Sp5, RMg, intermediate reticular (IRt), lateral (LRt), pre‐Bötzinger (preBötC), contralateral PiCo, laterodorsal tegmental (LDTg), pedunculopontine (PPTg), periaqueductal gray matter (PAG), Kölliker–Fuse (KF), PB, external cortex inferior colliculus (ECIC). A rabies virus (RV) retrograde transsynaptic approach was taken with EnvA‐pseudotyped G‐deleted (RV‐SAD‐G‐GFP) similarly target following prior injections helper AAVs (a mixture AAV‐Ef1a‐Con/Fon oG vector AAV8‐Con/Fon‐TVA‐mCherry). This combined prominent synaptic inputs from NTS, IRt, A1/C1. Although project axons area, this did not detect direct connections. We suggest serves as critical integration site, projecting receiving neuronal implicated breathing, arousal, swallowing, autonomic regulation.

Language: Английский

Citations

0
Context-dependent activation of a social behavior brain network associates with learned vocal production DOI Creative Commons
Katherine L. Anderson,

Lionel Colón,

Violet Doolittle

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Feb. 17, 2023

In zebra finches, an avian brain network for vocal control undergoes context-dependent patterning of song-dependent activation. Previous studies in finches also implicate the importance dopaminergic input producing context-appropriate singing behavior. mice, it has been shown that oxytocinergic neurons originated paraventricular nucleus hypothalamus (PVN) synapse directly onto dopamine ventral tegmental area (VTA), implicating necessity oxytocin signaling from PVN a song. Both and non-avian axonal tract-tracing indicate high levels innervation by social behavior network. Here, we hypothesize motivation to trigger release originates network, highly conserved interconnected collection six regions implicated various homeostatic behaviors. We found expression neuronal activity marker EGR1 was not strongly correlated with song production any However, when were normalized rate, significantly higher except medial preoptic during female-directed context compared non-social undirected context. Our results suggest within male finch influences synaptic projection VTA, which turn signals allow production.

Language: Английский

Citations

1
»Polyvagal«: Die schöne Theorie und die hässlichen Fakten DOI

Daniel Walz,

Paul Grossman

Psychotherapie, Journal Year: 2024, Volume and Issue: 29(2), P. 163 - 174

Published: Oct. 1, 2024

Die Polyvagal-Theorie von Stephen Porges postuliert verschiedene wissenschaftliche Disziplinen wie Anatomie, Physiologie, Psychophysiologie, Evolutionsund Entwicklungsbiologie, Sozialwissenschaften und Psychotherapie zu integrieren menschliches Verhalten, insbesondere in nach Stresssituationen, auf eine evolutionäre Besonderheit des Nervus vagus bei Säugetieren zurückführen können. Dabei werden neuroanatomische Hypothesen zum mit sozialen psychologischen Konzepten verknüpft. Vor allem unter Traumatherapeuten findet die Theorie seit Jahren zunehmende Verbreitung wird teilweise als bahnbrechend bezeichnet, so auch der letzten Ausgabe dieser Zeitschrift (Ackermann, 2024; Grassmann, Rahm & Meggyesy, 2024). v. a. Konzepte rezipiert. Allerdings besteht Experten weitgehend Konsens, dass grundlegenden physiologischen Annahmen nicht haltbar sind widerlegt gelten müssen. Darüber hinaus wichtigsten – z. B. Bindung, Ko-Regulation, soziale Interaktion unbewusste Wahrnehmungsprozesse schon Jahrzehnte älter polyvagalen benötigen für ihre Anwendung Psychologie oder keine Begründungen. Für diejenigen, ein biologisches Verständnis Prozesse anstreben, gibt es andere Erklärungsmodelle, das gesamte Nervensystem einbeziehen dem heutigen wissenschaftlichen »Embodiment« besser entsprechen.

Citations

0
Two conserved vocal central pattern generators broadly tuned for fast and slow rates generate species-specific vocalizations inXenopusclawed frogs DOI Creative Commons
Ayako Yamaguchi,

Manon Peltier

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Jan. 28, 2023

ABSTRACT Across phyla, species-specific vocalizations are used by males to attract females. Functional analyses of the neural circuitry underlying behavior have been difficult, particularly in vertebrates. However, using an ex vivo brain preparation that produces fictive vocalizations, we previously identified anatomically distinct fast and slow central pattern generators (CPGs) drive clicks male courtship calls African clawed frogs, Xenopus laevis . To gain insight into evolution circuits calls, extended this approach four additional species. Here, show although exact rate duration unique each species, CPGs X. conserved across Further, development depends on testosterone a manner: facilitates species with call containing clicks, but not made entirely clicks. Finally, showed that, unlike other vestigial remain latent, inherited all species; rather, they possessed only produce The results suggest genus evolved utilizing or broadly tuned generate trains which appear be regulated strategic expression receptors

Language: Английский

Citations

0