Comprehensive Review of in vitro Gut-Brain Axis Models in Parkinson’s Disease Research

Brain Organoid and Systems Neuroscience Journal, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

From the Gut to the Brain: Is Microbiota a New Paradigm in Parkinson’s Disease Treatment?

Cells, Journal Year: 2024, Volume and Issue: 13(9), P. 770 - 770

Published: April 30, 2024

Parkinson’s disease (PD) is recognized as the second most prevalent primary chronic neurodegenerative disorder of central nervous system. Clinically, PD characterized a movement disorder, exhibiting an incidence and mortality rate that increasing faster than any other neurological condition. In recent years, there has been growing interest concerning role gut microbiota in etiology pathophysiology PD. The establishment brain–gut axis now real, with evidence denoting bidirectional communication between brain through metabolic, immune, neuronal, endocrine mechanisms pathways. Among these, vagus nerve represents direct form gut. Given potential interactions bacteria drugs, it observed therapies for can have impact on composition microbiota. Therefore, scope present review, we will discuss current understanding whether this may be new paradigm treating devastating disease.

Language: Английский

Bibliometric analysis of electroencephalogram research in Parkinson’s disease from 2004 to 2023

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: July 19, 2024

Parkinson's disease (PD) is a prevalent neurodegenerative disorder affecting millions globally. It encompasses both motor and non-motor symptoms, with notable impact on patients' quality of life. Electroencephalogram (EEG) non-invasive tool that increasingly utilized to investigate neural mechanisms in PD, identify early diagnostic markers, assess therapeutic responses.

Language: Английский