International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(3), P. 1806 - 1806
Published: Feb. 2, 2024
The
gut
microbiota
of
healthy
breastfed
infants
is
often
dominated
by
bifidobacteria.
In
an
effort
to
mimic
the
infants,
modern
formulas
are
fortified
with
bioactive
and
bifidogenic
ingredients.
These
ingredients
promote
optimal
health
development
as
well
infant
microbiota.
Here,
we
used
INFOGEST
in
vitro
batch
fermentation
model
investigate
health-promoting
effects
a
commercial
formula
supplemented
blend
containing
docosahexaenoic
acid
(DHA)
(20
mg/100
kcal),
polydextrose
galactooligosaccharides
(PDX/GOS)
(4
g/L,
1:1
ratio),
milk
fat
globule
membrane
(MFGM)
(5
g/L),
lactoferrin
(0.6
Bifidobacterium
animalis
subsp.
lactis,
BB-12
(BB-12)
(106
CFU/g).
Using
fecal
inoculates
from
three
assessed
changes,
effect,
short-chain
fatty
(SCFA)
production
test
compared
those
data
obtained
unsupplemented
base
breast
control.
Our
results
show
that
even
after
digestion
formula,
can
still
maintain
its
bioactivity
modulate
infants'
composition,
faster
bifidobacterial
growth,
stimulate
SCFAs.
Thus,
it
may
be
concluded
promotes
SCFA
profile
something
similar,
but
not
identical
infants.
Meditsinskiy sovet = Medical Council,
Journal Year:
2025,
Volume and Issue:
1, P. 32 - 39
Published: April 2, 2025
Adequate
nutrition
during
the
first
months
of
life
is
essential
for
newborns
and
infants
to
ensure
their
growth
development.
If
women
are
unable
breastfeed
medical
or
social
reasons,
milk
formulas
become
primary
source
infants.
Modern
infant
developed
with
due
account
latest
discoveries
in
science
regarding
growing
body
needs
include
various
functional
components
that
contribute
a
baby’s
healthy
However,
histories
creation
evolution
always
interesting.
The
article
describes
how
different
nations
approached
issues
feeding
babies
using
alternatives
breast
milk,
including
goat’s
cow’s
as
well
plant-based
formulas.
Special
attention
paid
research
field
medicine
inspired
safe
nutritional
Currently,
rapid
technological
advancements
can
provide
modern
formula-fed
oligosaccharides
structures
identical
human
oligosaccharides,
polyunsaturated
fatty
acids
(omega-3
omega-6)
such
docosahexaenoic
acid
(DHA)
arachidonic
(ARA)
other
useful
components.
New
artificial
and/or
mixed
from
birth
stand
out
particularly.
Their
composition
meets
all
requirements
production
formula
enriched
combination
2′-fucosylated
(2′-FL)
galacto-oligosaccharides
(GOS),
which
give
long-range
outlook
use
Critical Reviews in Food Science and Nutrition,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 23
Published: April 11, 2025
Probiotics
offer
substantial
health
benefits,
leading
to
their
increased
consumption
in
various
food
products.
The
viability
of
probiotics
is
a
critical
factor
that
influences
the
nutritional
and
therapeutic
efficacy
these
foods.
However,
as
often
lose
during
production
oral
administration,
effective
preservation
encapsulation
technologies
are
needed
overcome
this
challenge.
This
review
elucidates
diverse
sources
incorporation
strategies
probiotics,
while
systematically
analyzing
effects
water
transformation
(ice
front
velocity,
glass
transition
temperature,
collapse
temperature),
processing
conditions
(food
matrix,
dissolved
oxygen),
gastrointestinal
challenges
(gastric
fluid,
digestive
enzymes,
bile
salts)
on
probiotic
viability.
Effective
strengthen
encompass
three
primary
domains:
fermentation
processes,
techniques,
methods.
Specifically,
include
meticulous
control
(nitrogen
sources,
lipids,
carbon
sources),
pre-stress
treatments
(pre-cooling,
heat
shock,
NaCl
stress,
acid
stress),
optimized
lyoprotectant
selection
(carbohydrates,
proteins,
polyols),
synergistic
freeze-drying
(infrared
technology,
spray
drying,
microwave),
bulk
approaches
(polysaccharide
or
protein-based
microencapsulation),
single-cell
methods
(self-assembly
surface
functionalization).
Despite
advancements,
targeting
specific
matrices
remains
challenging,
necessitating
further
research
enhance
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(3), P. 1806 - 1806
Published: Feb. 2, 2024
The
gut
microbiota
of
healthy
breastfed
infants
is
often
dominated
by
bifidobacteria.
In
an
effort
to
mimic
the
infants,
modern
formulas
are
fortified
with
bioactive
and
bifidogenic
ingredients.
These
ingredients
promote
optimal
health
development
as
well
infant
microbiota.
Here,
we
used
INFOGEST
in
vitro
batch
fermentation
model
investigate
health-promoting
effects
a
commercial
formula
supplemented
blend
containing
docosahexaenoic
acid
(DHA)
(20
mg/100
kcal),
polydextrose
galactooligosaccharides
(PDX/GOS)
(4
g/L,
1:1
ratio),
milk
fat
globule
membrane
(MFGM)
(5
g/L),
lactoferrin
(0.6
Bifidobacterium
animalis
subsp.
lactis,
BB-12
(BB-12)
(106
CFU/g).
Using
fecal
inoculates
from
three
assessed
changes,
effect,
short-chain
fatty
(SCFA)
production
test
compared
those
data
obtained
unsupplemented
base
breast
control.
Our
results
show
that
even
after
digestion
formula,
can
still
maintain
its
bioactivity
modulate
infants'
composition,
faster
bifidobacterial
growth,
stimulate
SCFAs.
Thus,
it
may
be
concluded
promotes
SCFA
profile
something
similar,
but
not
identical
infants.
