Separations,
Journal Year:
2024,
Volume and Issue:
11(12), P. 342 - 342
Published: Nov. 28, 2024
Food
quality
and
safety
are
critical
public
health
concerns,
with
approximately
600
million
people
worldwide
being
affected
by
foodborne
diseases
each
year
due
to
contamination.
These
not
only
lead
a
notable
number
of
deaths
but
also
impose
substantial
economic
burdens,
especially
in
low-
middle-income
countries.
Given
the
severe
risks
posed
food
contaminants,
developing
advanced,
sensitive
analytical
methods
detect
such
contaminants
is
essential.
Contemporary
challenges
include
detecting
at
trace
levels
managing
cumulative
from
simultaneous
exposure
multiple
chemicals.
Liquid
chromatography,
particularly
combination
high-resolution
mass
spectrometry
(LC/MS),
has
proven
indispensable
for
key
as
perfluoroalkyl
polyfluoroalkyl
substances,
polycyclic
aromatic
hydrocarbons,
pesticides,
veterinary
residues,
packaging-derived
mycotoxins,
pyrrolizidine
alkaloids
various
matrices.
The
present
article
reviews
recent
studies
on
subject
published
between
2020
2023.
International Journal of Advanced Science and Engineering,
Journal Year:
2023,
Volume and Issue:
10(2), P. 3449 - 3470
Published: Nov. 25, 2023
Emerging
contaminants,
including
pharmaceutical
drug
molecules,
personal
care
products,
and
microplastics,
are
frequently
present
in
the
environmental
samples.These
derived
from
various
sources
of
municipal
wastewater
discharges,
domestic
solid
waste
dumped
on
land,
disposal
farmlands,
industrial
discharges.These
may
cause
innumerous
hazardous
effects,
particularly
endocrine
disruption
to
all
organisms
exposed
such
contaminants.The
treated
sewage
sludge
is
applied
agricultural
field
without
screening
for
emerging
contaminants.As
a
result
toxicity
organisms,
antibiotic-resistant
bacteria
disseminated
environment
due
occurrence
antibacterial
drugs
samples.It
reported
that
more
than
200
different
kinds
were
found
river
water,
ciprofloxacin
concentration
was
up
6.5
mg/l.Global
water
scarcity
has
major
impact
agriculture,
leading
use
farmland.The
United
States
Environmental
Protection
Agency
(EPA)
recognizes
products
(PPCPs)
as
carcinogens
disruptors.Many
scientists
have
recently
these
novel
contaminants
toxic
can
affect
health.This
paper
critically
analyzes
their
health.Further,
it
presents
viable
solutions
manage
control
them
through
analytical
techniques,
artificial
intelligence,
machine
learning
methods.
Electrospray
ionization
mass
spectrometry
has
long
been
the
standard
and
most
prevalent
method
in
to
detect
analyze
molecules
of
low
volatility
that
are
relevant
biologically,
environmentally,
industrially.
However,
only
a
small
number
analyses
conducted
negative
ion
mode,
which
led
dog-matic
bias
toward
positive
mode
despite
advantageous
properties
polarity,
including
lower
back-ground
noise
divergent
tandem
behavior.
We
hypothesized
this
was
rooted
relatively
poor
efficiency
anionic
functional
groups
seen
biochemistry;
explore
notion
herein
we
evaluated
25
ions
based
on
three
criteria:
(1)
signal
intensity
relative
sodium
dodecylsulfate
internal
stand-ard;
(2)
resistance
collision
induced
dissociation
survival
precursor
ion;
(3)
diagnostic
Among
these
species,
highly
fluorous
exhibiting
weakly
coordinating
hydro-phobic
contributed
enhanced
intensities.
Trifluoromethanesulfonyl-containing
proved
be
unexpectedly
labile,
while
tetrakis[3,5-bis(trifluoromethyl)phenyl]borate
anion
(23)
bis(nonafluoro-1-butane)sulfonimidate
(25)
were
determined
optimal
with
ratios
(12
+
Na+)
332.0%
±
25.0%
939.0%
92.0%,
respectively,
as
well
yields
100.0%
0.0%
72.6%
0.8%
at
–50
eV.
To
further
emphasize
their
intensity,
comparable
across
solvents
acetonitrile,
methanol,
isopropanol,
water,
respective
1:1
mixtures.
Facile
preparation
various
salts
additional
evaluation
cation
effects
where
ratio
ranged
from
92.0%
3195.0%
145.0%
K+,
NH4+,
Na+,
H+
counter
cations.
The
dogma
being
less
sensitive
then
challenged
by
analysis
sig-nal
tetra-n-butylammonium,
tetra-n-butylphosphonium,
(4-methylphenyl)diphenylsulfonium
These
experiments
showed
more
between
136.2%
5.5%
180.7%
13.8%,
thereby
successfully
challenging
polarity
bias.
Electrospray
ionization
mass
spectrometry
has
long
been
the
standard
and
most
prevalent
method
in
to
detect
analyze
molecules
of
low
volatility
that
are
relevant
biologically,
environmentally,
industrially.
However,
only
a
small
number
analyses
conducted
negative
ion
mode,
which
led
dogmatic
bias
toward
positive
mode
despite
advantageous
properties
polarity,
including
lower
back-ground
noise
divergent
tandem
behavior.
We
hypothesized
this
was
rooted
relatively
poor
efficiency
anionic
functional
groups
seen
biochemistry;
explore
notion
herein
we
evaluated
25
ions
based
on
three
criteria:
(1)
signal
intensity
relative
sodium
dodecylsulfate
internal
standard;
(2)
resistance
collision
induced
dissociation
survival
precursor
ion;
(3)
diagnostic
Among
these
species,
highly
fluorous
exhibiting
weakly
coordinating
hydro-phobic
contributed
enhanced
intensities.
Trifluoromethanesulfonyl-containing
proved
be
unexpectedly
labile,
while
tetrakis[3,5-bis(trifluoromethyl)phenyl]borate
anion
(23)
bis(nonafluoro-1-butane)sulfonimidate
(25)
were
determined
optimal
with
ratios
(12
+
Na+)
332.0%
±
25.0%
939.0%
92.0%,
respectively,
as
well
yields
100.0%
0.0%
72.6%
0.8%
at
–50
eV.
To
further
emphasize
their
intensity,
comparable
across
solvents
acetonitrile,
methanol,
isopropanol,
water,
respective
1:1
mixtures.
Facile
preparation
various
salts
additional
evaluation
cation
effects
where
ratio
ranged
from
92.0%
3195.0%
145.0%
K+,
NH4+,
Na+,
H+
counter
cations.
The
dogma
being
less
sensitive
then
challenged
by
analysis
sig-nal
tetra-n-butylammonium,
tetra-n-butylphosphonium,
(4-methylphenyl)diphenylsulfonium
These
experiments
showed
more
between
136.2%
5.5%
180.7%
13.8%,
thereby
successfully
challenging
polarity
bias.
Electrospray
ionization
mass
spectrometry
has
long
been
the
standard
and
most
prevalent
method
in
to
detect
analyze
molecules
of
low
volatility
that
are
relevant
biologically,
environmentally,
industrially.
However,
only
a
small
number
analyses
conducted
negative
ion
mode,
which
led
dogmatic
bias
toward
positive
mode
despite
advantageous
properties
polarity,
including
lower
background
noise
divergent
tandem
behavior.
We
hypothesized
this
was
rooted
relatively
poor
efficiency
anionic
functional
groups
seen
biochemistry;
explore
notion
herein
we
evaluated
25
ions
based
on
three
criteria:
(1)
signal
intensity
relative
sodium
dodecylsulfate
internal
standard;
(2)
resistance
collision
induced
dissociation
survival
precursor
ion;
(3)
diagnostic
Among
these
species,
highly
fluorous
exhibiting
weakly
coordinating
hydrophobic
contributed
enhanced
intensities.
Trifluoromethanesulfonyl-containing
proved
be
unexpectedly
labile,
while
tetrakis[3,5-bis(trifluoromethyl)phenyl]borate
anion
(23)
bis(nonafluoro-1-butane)sulfonimidate
(25)
were
determined
optimal
with
ratios
(12
+
Na+)
332.0%
±
25.0%
939.0%
92.0%,
respectively,
as
well
yields
100.0%
0.0%
72.6%
0.8%
at
–50
eV.
To
further
emphasize
their
intensity,
comparable
across
solvents
acetonitrile,
methanol,
isopropanol,
water,
respective
1:1
mixtures.
Facile
preparation
various
salts
additional
evaluation
cation
effects
where
ratio
ranged
from
92.0%
3195.0%
145.0%
K+,
NH4+,
Na+,
H+
counter
cations.
The
dogma
being
less
sensitive
then
challenged
by
analysis
tetra-n-butylammonium,
tetra-n-butylphosphonium,
(4-methylphenyl)diphenylsulfonium
These
experiments
showed
more
between
136.2%
5.5%
180.7%
13.8%,
thereby
successfully
challenging
polarity
bias.
Analytical and Bioanalytical Chemistry,
Journal Year:
2024,
Volume and Issue:
416(7), P. 1541 - 1560
Published: Feb. 13, 2024
Abstract
The
development
and
validation
of
a
simple,
comprehensive,
environment-friendly
procedure
to
determine
pesticide
residues,
naturally
occurring
processing
contaminants
in
roasted
coffee
is
presented.
A
solid-liquid
extraction
pesticides
mycotoxins
with
ethyl
acetate
the
concurrent
partition
acrylamide
an
aqueous
phase
follows
parallel
analytical
strategy
that
requires
single
portion
are
typically
analyzed
by
dedicated
residue
methods.
rules
lipids
out
extract
before
“in-tube”
dispersive
solid
microextraction
(dSPME)
for
retention.
This
followed
elution
buffer
prior
injection.
independently
introduced
into
system
front
end
injection
compounds
from
organic
phase,
yet
all
spotted
same
run.
novel
liquid
chromatography
high-resolution
mass
spectrometry
(LC-HRMS)
method
setup
enables
quantification
186
at
10
µg/kg,
226
5
200
µg/kg
total
414
molecules,
acceptable
recoveries
(70–120%)
precision
(RSD
<
20%)
making
this
significantly
faster
cost-effective
than
Even
though
presence
chlorpyrifos,
acrylamide,
ochratoxin
was
confirmed
on
samples
different
origins,
findings
were
below
limit
quantification.
During
storage
raw
coffee,
no
proof
masking
OTA
found;
however,
condensation
glucose
evidenced
during
thermal
experiments
sucrose
using
stable
isotope
labeling
(SIL).
No
detected
conjugates
found
nor
commercial
sugar-added
torrefacto
samples,
industrial
usually
carried
above
decomposition
temperature
disaccharide.
Graphical
abstract
