Published: Sept. 1, 2017
Language: Английский
Neurosurgery, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 29, 2025
BACKGROUND AND OBJECTIVES: The risk-to-benefit ratio of transopercular awake resection for recurrent insular diffuse gliomas is poorly studied. We assessed feasibility, safety, and efficacy surgical in patients with previous treatments (resection and/or radiotherapy chemotherapy combination). METHODS: Observational, retrospective, single-institution cohort analysis (2010-2023) 123 consecutive adult operated on an glioma (2021 World Health Organization classification) under conditions. Comparison between as first-line treatment (n = 87) after 36). RESULTS: Function-based a (1) did not increase intraoperative adverse events compared resection; (2) was associated higher rate insufficient cooperation combined oncological (33.3%), monotherapeutic modality (7.4%), surgery (8.1%, P .046); (3) resulted rates similar to those at (median 91.9%, vs 90.1%); (4) surgery-related complications or duration hospital stay; (5) worsen the 6-month Karnofsky Performance Status score, seizure control, sick leave; (6) influence leave from work, but longer high-grade (38.0% 7.7%, < .001). CONCLUSION: seems feasible safe recurrence previously treated glioma, outcomes than first-time surgery.
Language: Английский
Citations
0
Revue Neurologique, Journal Year: 2023, Volume and Issue: 179(5), P. 437 - 448
Published: March 10, 2023
Language: Английский
Citations
6
Annals of Medicine and Surgery, Journal Year: 2024, Volume and Issue: unknown
Published: Feb. 22, 2024
Direct cortical stimulation has been used for brain mapping and localization of eloquent areas in awake patients. This simplified technique is to provide the positive areas, which can be preserved if tumor or lesions are involved areas.
Language: Английский
Citations
1
Acta Neurochirurgica, Journal Year: 2024, Volume and Issue: 166(1)
Published: Oct. 28, 2024
Language: Английский
Citations
1
Journal of Neuro-Oncology, Journal Year: 2024, Volume and Issue: 171(3), P. 485 - 493
Published: Nov. 18, 2024
Previous evidence suggests that glioma re-resection can be effective in improving clinical outcomes. Furthermore, the use of mapping techniques during surgery has proven beneficial for newly diagnosed patients. However, effects these are not clear. This systematic review aimed to assess using recurrent A search was performed identify relevant studies. Articles were eligible if they included adult patients with gliomas (WHO grade 2–4) who underwent re-resection. Study characteristics, application mapping, and surgical outcome data on survival, patient functioning, complications extracted. The literature strategy identified 6372 articles, which 125 screened eligibility. After full-text evaluation, 58 articles this review, comprising 5311 glioma. Of 17% (10/58) reported awake or asleep intraoperative Mapping applied 5% (280/5311) all patients, craniotomy used 3% (142/5311) re-resection, some it is useful improve there a lack high-quality support techniques. low number studies reporting may, next publication bias, reflect limited setting. We advocate future determine their utility reducing morbidity increasing extent resection, similar benefits primary
Language: Английский
Citations
1
Journal of Personalized Medicine, Journal Year: 2022, Volume and Issue: 12(10), P. 1621 - 1621
Published: Oct. 1, 2022
Diffuse low-grade glioma (LGG) is a rare cerebral cancer, mostly involving young adults with an active life at diagnosis. If left untreated, LGG widely invades the brain and becomes malignant, generating neurological worsening ultimately death. Early repeat treatments for this incurable tumor, including maximal connectome-based surgical resection(s) in awake patients, enable postponement of malignant transformation while preserving quality owing to constant neural network reconfiguration. Due considerable interindividual variability terms course consecutive reorganization, multistage longitudinal strategy should be tailored accordingly each patient. It crucial predict how will progress (changes growth rate pattern migration, genetic mutation, etc.) adapt patterns spatiotemporal redistribution, possible functional consequences such as epilepsy or cognitive decline, etc.). The goal anticipate therapeutic management, remaining one step ahead order select optimal (re-)treatment(s) (some them possibly kept reserve), appropriate time(s) evolution chronic disease, before malignization clinical worsening. Here, predictive tumoral non-tumoral factors, their ever-changing interactions, are reviewed guide individual decisions advance based on patient-specific markers, treatment LGG.
Language: Английский
Citations
6
World Neurosurgery, Journal Year: 2023, Volume and Issue: 177, P. e563 - e579
Published: June 28, 2023
Language: Английский
Citations
3
Neurosurgery, Journal Year: 2023, Volume and Issue: 93(4), P. e85 - e91
Published: April 19, 2023
Diffuse World Health Organization grade II glioma (GIIG) is a slow-growing brain cancer that migrates along the white matter (WM) tracts. Neuroplastic changes were described in reaction to GIIG progression, opening window extensive cerebral surgical resection patients able resume an active life with no functional consequences. However, atlases of cortico-subcortical neural plasticity emphasized limited potential axonal reorganization. Yet, removal WM involved by can be possible, at least some extent, without generating permanent neurological disturbances. Here, aim was discuss mechanisms underlying compensation which make feasible subcortical component and propose new model adaptative reconfiguration level connectivity. In this model, 2 parts tracts are considered: (1) stem bundle represents actual limitation plastic potential, as supported reproducible behavioral disorders elicited intraoperative electrostimulation mapping (ESM) (2) terminations/origins may longer critical case reallocation cortex to/from these fibers run-thus inducing troubles during direct ESM. Understanding certain degree specific portions driven cortical remodeling enable rethink concept refine preoperative estimation extent for GIIG. Identifying eloquent ESM, especially their convergence depth, essential achieve individualized connectome-based resection.
Language: Английский
Citations
2
Neurosurgical Review, Journal Year: 2024, Volume and Issue: 47(1)
Published: March 27, 2024
Language: Английский
Citations
0
Bulletin de l Académie Nationale de Médecine, Journal Year: 2024, Volume and Issue: 208(6), P. 824 - 831
Published: April 26, 2024
Citations
0