Bibliometric analysis of global research trends between gut microbiota and breast cancer: from 2013 to 2023 DOI Creative Commons
Xianguang Deng,

Hua Yang,

Lingjia Tian

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: July 31, 2024

Background Breast cancer is the most prevalent globally and associated with significant mortality. Recent research has provided crucial insights into role of gut microbiota in onset progression breast cancer, confirming its impact on disease’s management. Despite numerous studies exploring this relationship, there a lack comprehensive bibliometric analyses to outline field’s current state emerging trends. This study aims fill that gap by analyzing key directions identifying hotspots. Method Publications from 2013 2023 were retrieved Web Science Core Collection database. The VOSviewer, R language SCImago Graphica software utilized analyze visualize volume publications, countries/regions, institutions, authors, keywords field. Results A total 515 publications included study. journal Cancers was identified as prolific, contributing 21 papers. United States China leading contributors University Alabama at Birmingham productive institution. Peter Bai published papers, while James J. Goedert cited author. Analysis highly literature keyword clustering confirmed close relationship between cancer. Keywords such “metabolomics” “probiotics” have been prominently highlighted analysis, indicating future hotspots interaction metabolites microenvironment microbiota. Additionally, these suggest interest therapeutic potential probiotics for treatment. Conclusion Research expanding. Attention should be focused understanding mechanisms their interaction, particularly metabolite-microbiota-breast crosstalk. These advance prevention, diagnosis, treatment strategies provides assessment trends field, offering valuable perspectives

Language: Английский

Polyethylene microplastics induced gut microbiota dysbiosis leading to liver injury via the TLR2/NF-κB/NLRP3 pathway in mice DOI
Ran Xu,

Jing-wen Cao,

Hongli Lv

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 917, P. 170518 - 170518

Published: Jan. 28, 2024

Language: Английский

Citations

38
Butyrate’s (a short-chain fatty acid) microbial synthesis, absorption, and preventive roles against colorectal and lung cancer DOI
Md Rezaul Karim, Safia Iqbal, Shahnawaz Mohammad

et al.

Archives of Microbiology, Journal Year: 2024, Volume and Issue: 206(4)

Published: March 4, 2024

Language: Английский

Citations

16
Role of the gut microbiota in tumorigenesis and treatment DOI Creative Commons
Qingya Liu,

Yun Yang,

Meng Pan

et al.

Theranostics, Journal Year: 2024, Volume and Issue: 14(6), P. 2304 - 2328

Published: Jan. 1, 2024

The gut microbiota is a crucial component of the intricate microecosystem within human body that engages in interactions with host and influences various physiological processes pathological conditions.In recent years, association between dysbiosis tumorigenesis has garnered increasing attention, as it recognized hallmark cancer scientific community.However, only few microorganisms have been identified potential drivers tumorigenesis, enhancing molecular understanding this process substantial importance clinical relevance for treatment.In review, we delineate impact on treatment multiple types while also analyzing associated mechanisms.Moreover, discuss utility data diagnosis patient stratification.We further outline current research harnessing prospects challenges approach.

Language: Английский

Citations

12
Research Hotspots of Interferon Gamma in the Treatment of Lung Cancer: A Bibliometric Analysis Based on CiteSpace DOI

Zhen Lv,

Jian Wu

Journal of Interferon & Cytokine Research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

Interferon-gamma (IFN-γ) is an important cytokine associated with antitumor immunity and has been implicated in the pathogenesis progression of lung cancer. Nevertheless, no bibliometric analyses have published this field to date, thus we aim address gap knowledge. A search Web Science (WOS) for literature related treatment cancer IFN-γ was conducted from 2002 2024. The extracted information included articles subjected visual analysis, network diagrams were generated using software such as CiteSpace VOSviewer. In total, 589 WOS between number citation frequency generally showed increasing trend year by year. United States University California are countries institutions largest articles. researcher who made contribution Xin Cai China (6). Journal ImmunoTherapy Cancer relevant papers (16 papers, IF = 12.469). research hotspots immune escape recent years IFN-γ, mechanism, checkpoints, microtumor inhibitors. evolving at a rapid pace. current focus within on elucidating mechanism cancer, investigating role checkpoint inhibitors, examining tumor microenvironment other pertinent topics.

Language: Английский

Citations

0
Global trends in resistance studies of gemcitabine and pancreatic cancer: a bibliometric and visual analysis from 2010 to 2024 DOI Creative Commons

Dandan Gu,

Shaoyang Huang, Kai Zhao

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 16

Published: April 25, 2025

Pancreatic adenocarcinoma (PC) represents a prevalent and highly aggressive malignancy within the digestive system, characterized by an exceedingly poor prognosis dismal 5-year survival rate of below 7%. Gemcitabine (GEM) remains cornerstone chemotherapeutic agent in management PC; however, growing challenge GEM chemoresistance, which undermines treatment efficacy, significant obstacle clinical practice. To date, no comprehensive bibliometric analysis has been undertaken to systematically explore studies on resistance context PC. This study aims deliver thorough evaluation research hotspots pertaining PCs. A systematic search was conducted for articles published from 1 January 2010, 15 December 2024, focusing Bibliometric visualization were performed utilizing VOSviewer CiteSpace tools, applied literature data extracted Web Science Core Collection (WoSCC). Between 2010 total 2,689 papers across 472 institutions 74 countries, reflecting consistent upward trajectory annual publication output. China Fudan University emerged as leading contributors output this topic, representing most prolific country institution, respectively. Giovannetti, Elisa, Yu, Xianjun are scholars field. Cancer Research stands out cited impactful journal, while tumor microenvironment, targeted therapy, circular RNA key focus area recent years. provides overview PC over past offers critical insights into field perspective, potentially informing future development treatments

Language: Английский

Citations

0
Global research and current trends on nanotherapy in lung cancer research: a bibliometric analysis of 20 years DOI Creative Commons
Pooja Singh, Prabhakar Semwal,

Baby Gargi

et al.

Discover Oncology, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 9, 2024

Lung cancer ranks as one of the most rapidly growing malignancies. Which is characterized by its poor prognosis and a low survival rate due to late diagnosis limited efficacy conventional treatments. In recent years nanotechnology has emerged promising frontier in management lung cancer, presenting novel strategies enhance drug administration, improve therapeutic efficiency, mitigate side effects. This research comprehensively evaluates current state trends concerning application nanomaterials through bibliometric analysis.

Language: Английский

Citations

2
Unveiling the hidden world of gut health: Exploring cutting-edge research through visualizing randomized controlled trials on the gut microbiota DOI Open Access
Sa’ed H. Zyoud,

Muna Shakhshir,

Amani S. Abushanab

et al.

World Journal of Clinical Cases, Journal Year: 2023, Volume and Issue: 11(26), P. 6132 - 6146

Published: Sept. 8, 2023

The gut microbiota plays a crucial role in gastrointestinal and overall health. Randomized clinical trials (RCTs) play advancing our knowledge evaluating the efficacy of therapeutic interventions targeting microbiota.To conduct comprehensive bibliometric analysis literature on RCTs involving microbiota.Using tools, descriptive cross-sectional investigation was conducted scholarly publications concentrated related to microbiota, spanning years 2003 2022. study used VOSviewer version 1.6.9 examine collaboration networks between different countries evaluate frequently employed terms titles abstracts retrieved publications. primary objective this identify key research areas focal points associated with microbiota.A total 1061 relevant articles were identified from 24758 published number showed notable increase over time, positive correlation (R2 = 0.978, P < 0.001). China (n 276, 26.01%), United States 254, 23.94%), Kingdom 97, 9.14%) leading contributing countries. Københavns Universitet 38, 3.58%) Dankook University 35, 3.30%) top active institutions. co-occurrence shows current trends important topics, such as obesity safety fecal transplantation, effects dietary humans.The highlights rapid growth importance that involve microbiota. This provides valuable insight into trends, identifies players, outlines potential future directions field. Additionally, topics critical advancement science provided insights

Language: Английский

Citations

5
Bibliometric analysis of global research trends between gut microbiota and pancreatic cancer: from 2004 to 2023 DOI Creative Commons
Shuang Wu, Wen Su,

Kangli An

et al.

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 27, 2023

Background Pancreatic cancer (PC) is one of the most lethal malignancies digestive system and expected to be second leading cause cancer-related death in United States by 2030. A growing body evidence suggests that gut microbiota (GM) intimately involved clinical diagnosis, oncogenic mechanism treatment PC. However, no bibliometric analysis PC GM has been reported. Methods The literature on was retrieved from Web Science Core Collection (WoSCC) database for period January 1, 2004 April 25, 2023. Microsoft Excel 2021, CiteSpace, VOSviewer, Scimago Graphica, Graphpad Prism, Origin, R package “bibliometrics” online program were used visualize publishing trends hot spots this field. Results total 1,449 articles included, including 918 531 reviews. Publishing had grown rapidly since 2017, with 2023 publish 268 articles. Unsurprisingly, ranked highest terms number literatures, H index average citations. University California System active institution, but Harvard tended cited average. three influential researchers Robert M. Hoffman, Zhao Minglei, Zhang Yong. Cancers published papers, while Nature journal. Keyword theme indicated “tumor microenvironment,” “gemcitabine-resistance,” “ductal adenocarcinoma,” “gut microbiota” “diagnosis” will hotspots frontiers research future. Conclusion In summary, field receiving increasing attention. We found future PC/GM may focus oncogenesis, flora combination therapy exploitation new predictive biomarkers, which provides effective suggestions insights scholars.

Language: Английский

Citations

5
Pueraria thomsonii Benth-Associated Endophytes: A Multifaceted Exploration of Its Bioactive Molecules DOI
Yumin Li,

Y. P. Liu,

Yalan Ran

et al.

Indian Journal of Microbiology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 17, 2024

Language: Английский

Citations

1
Non-small cell lung cancer and metabolism research from 2013 to 2023: a visual analysis and bibliometric study DOI Creative Commons
Jin Yang, Wei Yang,

Jie Zhang

et al.

Frontiers in Oncology, Journal Year: 2024, Volume and Issue: 14

Published: May 28, 2024

Background As one of the most prevalent primary lung tumors, non-small cell cancer (NSCLC) has garnered considerable research interest due to its high metastasis rates and poor prognosis outcomes. Across different types, metabolic processes are required for tumors progression growth, thus interfering with such in NSCLC may therapeutically viable limiting/halting disease progression. Therefore, comprehending how contribute growth survival mechanisms cancers, including NSCLC, elucidate key functions underpinning tumor metabolism. However, no bibliometric analyses have been published this field, therefore we address knowledge gap here. Methods Between 2013 2023 (December 28 th ), articles related metabolism (NSCLC-Met) field were retrieved from Web Science Core Collection (WoSCC). To fully dissect NSCLC-Met directions articles, used Bibliometrix package R, VOSviewer CiteSpace software visually represent global trends hotspots. Results 2023, 2,246 retrieved, a continuous upward trend rapid development observed year on year. Cancers Cancer Research recording highest average citation numbers. Zhang Li China was prolific author, but number authors came USA. China, USA, Italy top three countries close cooperation identified between countries. Recent hotspots reflected by “lung adenocarcinoma”, “immunotherapy”, “nivolumab”, “checkpoint inhibitors”, “blockade”, “pembrolizumab”, while “gut microbiome”, “egfr” “dose painting” important topics researchers. Conclusion From our analyses, scientists can now explore new field. Further in-depth will undoubtedly provide more insights diagnostics, treatment, prognostics.

Language: Английский

Citations

1