Exosome-Based Advances in Pancreatic Cancer: The Potential of Mesenchymal Stem Cells DOI
S. Rahimian,

Kimia Mirkazemi,

Armita Kamali Nejad

et al.

Critical Reviews in Oncology/Hematology, Journal Year: 2024, Volume and Issue: 207, P. 104594 - 104594

Published: Dec. 26, 2024

Language: Английский

Dual-functional gallium/chitosan/silk/umbilical cord mesenchymal stem cell exosome sponge scaffold for diabetic wound by angiogenesis and antibacteria DOI
Xin Shi, Yabei Li,

Simiao Kang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 274, P. 133420 - 133420

Published: June 24, 2024

Language: Английский

Citations

7
Bioengineered Mesenchymal Stem/Stromal Cells in Anti-Cancer Therapy: Current Trends and Future Prospects DOI Creative Commons

Jesús I. Gil-Chinchilla,

A. Zapata, José M. Moraleda

et al.

Biomolecules, Journal Year: 2024, Volume and Issue: 14(7), P. 734 - 734

Published: June 21, 2024

Mesenchymal stem/stromal cells (MSCs) are one of the most widely used cell types in advanced therapies due to their therapeutic potential regulation tissue repair and homeostasis, immune modulation. However, use cancer therapy is controversial: they can inhibit proliferation, but also potentially promote tumour growth by supporting angiogenesis, modulation milieu increasing stem invasiveness. This opposite behaviour highlights need for careful nuanced MSCs treatment. To optimize anti-cancer effects, diverse strategies have bioengineered enhance targeting properties or deliver drugs. In this review, we highlight uses therapy, particularly as carriers targeted treatments natural tumour-homing capabilities. We discuss MSC-derived extracellular vesicles improve efficiency drug molecule delivery cells. Ongoing clinical trials evaluating these setting stage future advances MSC-based It critical identify broad potent applications solid agent position them effective therapeutics evolving field therapy.

Language: Английский

Citations

4
Mesenchymal stromal cell exosomes for drug delivery of prostate cancer treatments: a review DOI Creative Commons

Chengran Wang,

Yanling Feng,

Xianfang Rong

et al.

Stem Cell Research & Therapy, Journal Year: 2025, Volume and Issue: 16(1)

Published: Jan. 23, 2025

Interest in prostate cancer as a research topic has gradually increased. As result, series of innovative treatment strategies have emerged with an in-depth understanding the disease. Owing to their unique biological characteristics, mesenchymal stromal cell exosomes (MSC-Exos) garnered significant attention for potential deliver targeted drugs and enable precise treatment. Herein, MSC-Exos drug-delivery systems is reviewed. This review provides comprehensive introduction advantages these systems, current trends progress, well analysis challenges future directions. Moreover, this lays solid foundation continued development application MSC-Exos.

Language: Английский

Citations

0
Recent advances in the delivery of microRNAs via exosomes derived from MSCs, and their role in regulation of ferroptosis DOI
Mohamed J. Saadh,

Hanan Hassan Ahmed,

Gaurav Sanghvi

et al.

Pathology - Research and Practice, Journal Year: 2025, Volume and Issue: unknown, P. 155984 - 155984

Published: April 1, 2025

Language: Английский

Citations

0
Exosome-Based Advances in Pancreatic Cancer: The Potential of Mesenchymal Stem Cells DOI
S. Rahimian,

Kimia Mirkazemi,

Armita Kamali Nejad

et al.

Critical Reviews in Oncology/Hematology, Journal Year: 2024, Volume and Issue: 207, P. 104594 - 104594

Published: Dec. 26, 2024

Language: Английский

Citations

3