Heliotherapy for neonates with severe-to-hazardous hyperbilirubinemia: a randomized controlled, non-inferiority trial DOI Creative Commons
Bolajoko O. Olusanya,

Abieyuwa A. Emokpae,

O F Aina

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 27, 2024

Filtered-sunlight phototherapy (FSPT) that blocks ultraviolet light and reduces infrared radiation is safe non-inferior to intensive electric (IEPT) for treating mild-to-severe neonatal hyperbilirubinemia. In this randomized non-inferiority trial, the safety, efficacy, exchange transfusion (ET), mortality rates of FSPT versus IEPT among Nigerian neonates with severe-to-hazardous hyperbilirubinemia were investigated. Safety was defined as absence hyperthermia, hypothermia, dehydration, or sunburn; efficacy by proportion assessable treatment days during which total serum plasma bilirubin (TSB) increased < 0.2 mg/dL/hr newborns aged ≤ 72 h-old decreased > h-old. A day deemed if a neonate received ≥ 4 h, inferred differences within 10% margin. We enrolled 192 (admission TSB 62 mg/dL), assigned (n = 98) 94). effective on 94.2% compared 97.1% IEPT. The mean difference in between -2.9%, 95% CI: -7.6, 1.9). 2.6% who developed controlled no baby met criteria withdrawal safety reasons. Overall, 50.6% (39/77) 53.7% (51/95) had ET (p 0.89) 7 each group (9.1% vs 7.4%; p 0.86) died. conclusion, hyperbilirubinemia, it not associated significantly higher should be considered where practicable when cannot assured. Clinical Trials.gov Number: NCT02612727 (24/11/2015).

Language: Английский

Comparing the Effect of Kangaroo Mother Care on the Serum Bilirubin Level of Term Neonates With Hyperbilirubinemia Under Phototherapy DOI Open Access
Saikat Biswas, Utkarsh Bansal, Pragati Sisodia

et al.

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Introduction and objectives Neonatal jaundice is often treated by phototherapy. Phototherapy an inexpensive, uncomplicated, relatively safe treatment option. However, considering certain side effects associated with phototherapy the resultant mother-infant separation, measures to minimize exposure should be sought. Thus, this study was planned investigate of combining intermittent kangaroo mother care (KMC) on duration in neonatal hyperbilirubinemia (NNH). Materials methods It observational analytical study. All full-term breastfed infants older than 24 hours age bilirubin levels range were included. The newborns at time admission randomly assigned simple computer-generated randomization into two groups 26 cases each (control group KMC group). In both groups, conducted using standard methods. Infants received conjunction required treat NNH primary outcome. Results not significantly different terms gender, type delivery, gestational age, infant's mean birth weight, onset jaundice, indicating homogenous groups. median higher control (p = 0.022). consistently showed group: (13.2 mg/dL vs. 11.7 mg/dL, p 0.047) 48 (11.7 9.9 0.038). Conclusion These findings indicate that complementary may reduce jaundice.

Language: Английский

Citations

0
Prevalence and factors associated with maternal and neonatal sepsis in sub-Saharan Africa: a systematic review and meta-analysis DOI Creative Commons
Fatoumata Traoré, Cheick Sidya Sidibé,

E. Diallo

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Jan. 24, 2024

Objectives This study aimed to determine the prevalence and factors associated with maternal neonatal sepsis in sub-Saharan Africa. Methods systematic review meta-analysis used PRISMA guideline on data The bibliographic search was carried out following databases: Medline/PubMed, Cochrane Library, African Index Medicus, Google Scholar. Additionally, reference lists of included studies were screened for potentially relevant studies. last conducted 15 October 2022. Joanna Briggs Institute quality assessment checklist applied critical appraisal. Estimates pooled using a random-effects model. Heterogeneity between estimated Q statistic I2 statistic. funnel plot Egger’s regression test assess publication bias. Results A total 39 our review: 32 7 sepsis. overall Sub-Saharan Africa 19.21% (95% CI, 11.46–26.97) 36.02% (CI: 26.68–45.36), respectively. meta-analyses revealed that Apgar score &lt; (OR: 2.4, 95% CI: 1.6–3.5), meconium amniotic fluid 2.9, 1.8–4.5), prolonged rupture membranes &gt;12 h 2.8, 1.9–4.1), male sex 1.2, 1.1–1.4), intrapartum fever 1.5–3.7), history urinary tract infection mother 2.7, 1.4–5.2) are Rural residence 2.3, 1.01–10.9), parity 0.5, 0.3–0.7), labor 3.4, 1.6–6.9), multiple digital vaginal examinations 4.4, 1.3–14.3) significantly Conclusion high Multiple identified. These could help prevention development strategies combat Given risk bias heterogeneity, further high-quality research is needed context, including individual data. Systematic registration: PROSPERO (ID: CRD42022382050).

Language: Английский

Citations

3
EVALUATION OF CORD BILIRUBIN FOR DEVELOPMENT OF SIGNIFICANT HYPERBILIRUBINEMIA IN HIGH-RISK TERM NEONATE DOI Open Access
M. M. A. Ahmed,

E. A. Darwish,

Ahmed Al-Sawah

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 27(1), P. 3859 - 3872

Published: Jan. 1, 2024

Neonatal jaundice occurs in approximately 60% of term newborns. Although risk factors for neonatal have been studied, all the suggested strategies are based on various newborn tests bilirubin levels.

Language: Английский

Citations

0
Integrative Review: Benefits, Challenges, and Perspectives Of Kangaroo Care in Neonatal Care DOI Creative Commons

Santiago Vasco-Morales,

Andrea Quinde-Arce, Fabiola Males-Jácome

et al.

Revista de Gestão Social e Ambiental, Journal Year: 2024, Volume and Issue: 18(8), P. e07165 - e07165

Published: June 13, 2024

Objective: Review the current scientific evidence on physiological effects of kangaroo care, explore barriers and facilitators to its implementation, identify areas knowledge that have not yet been explored. Theoretical Framework: The care method, despite benefits for premature low birth weight babies, faces implementation challenges. Its acceptance application vary due various factors, including cultural institutional ones, as well lack support mothers families. Method: Integrative review quantitative qualitative studies. critical appraisal studies was conducted using Joanna Briggs Institute tool. Principio del formulario Results Discussion: Evidence supports effectiveness in improving parameters neonate such heart rate, body temperature, oxygen saturation. main include: visiting hour restrictions, healthcare staff workload, negative beliefs, information empowerment mothers, limited involvement fathers. Research Implications: Provides how newborns, aspects influence implementation. Originality/Value: This study contributes literature by providing a comprehensive assessment effectiveness, safety, applicability neonatal care. It allows visualization identification improvement gaps may require future

Language: Английский

Citations

0
Heliotherapy for neonates with severe-to-hazardous hyperbilirubinemia: a randomized controlled, non-inferiority trial DOI Creative Commons
Bolajoko O. Olusanya,

Abieyuwa A. Emokpae,

O F Aina

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 27, 2024

Filtered-sunlight phototherapy (FSPT) that blocks ultraviolet light and reduces infrared radiation is safe non-inferior to intensive electric (IEPT) for treating mild-to-severe neonatal hyperbilirubinemia. In this randomized non-inferiority trial, the safety, efficacy, exchange transfusion (ET), mortality rates of FSPT versus IEPT among Nigerian neonates with severe-to-hazardous hyperbilirubinemia were investigated. Safety was defined as absence hyperthermia, hypothermia, dehydration, or sunburn; efficacy by proportion assessable treatment days during which total serum plasma bilirubin (TSB) increased < 0.2 mg/dL/hr newborns aged ≤ 72 h-old decreased > h-old. A day deemed if a neonate received ≥ 4 h, inferred differences within 10% margin. We enrolled 192 (admission TSB 62 mg/dL), assigned (n = 98) 94). effective on 94.2% compared 97.1% IEPT. The mean difference in between -2.9%, 95% CI: -7.6, 1.9). 2.6% who developed controlled no baby met criteria withdrawal safety reasons. Overall, 50.6% (39/77) 53.7% (51/95) had ET (p 0.89) 7 each group (9.1% vs 7.4%; p 0.86) died. conclusion, hyperbilirubinemia, it not associated significantly higher should be considered where practicable when cannot assured. Clinical Trials.gov Number: NCT02612727 (24/11/2015).

Language: Английский

Citations

0