Cardiopulmonary Exercise Testing in Children With Long COVID: A Case-controlled Study

The Pediatric Infectious Disease Journal, Journal Year: 2024, Volume and Issue: 43(8), P. 795 - 802

Published: May 7, 2024

Background: Cardiopulmonary exercise testing (CPET) is a noninvasive and nonexpensive diagnostic tool, that provides comprehensive evaluation of the pulmonary, cardiovascular, skeletal muscle systems’ integrated reactions to exercise. CPET has been extensively used in adults with Long COVID (LC), while evidence about its role children this condition scarce. Methods: Prospective, case-controlled observational study. Children LC control group healthy underwent CPET. findings were compared within 2 groups, groups according main clusters persisting symptoms. Results: Sixty-one 29 controls included. Overall, 90.2% patients (55 61) had pathologic test vs 10.3% (3/29) control. presented statistically significant higher probability having abnormal values peak VO2 ( P = 0.001), AT% pred <0.001), VO2/HR % 0.03), work slope 0.002), VE/VCO2 0.01). The mean was 30.17 (±6.85) 34.37 (±6.55) 0.007). Conclusions: Compared controls, have objective impaired functional capacity (expressed by low peak), signs deconditioning cardiogenic inefficiency when assessed As such, should be routinely clinical practice objectify phenotype limitations LC, follow-up them.

Language: Английский

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Characteristics and predictors of Long Covid in children: a 3-year prospective cohort study

EClinicalMedicine, Journal Year: 2024, Volume and Issue: 76, P. 102815 - 102815

Published: Sept. 5, 2024

Language: Английский

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Advances in researches on long coronavirus disease in children: a narrative review

Translational Pediatrics, Journal Year: 2024, Volume and Issue: 13(2), P. 318 - 328

Published: Feb. 1, 2024

In the context of global pandemic coronavirus disease 2019 (COVID-19), more than 700 million infections and millions deaths have occurred in countries around world. Currently, two main sequelae this are considered to occur children, namely, multi-system inflammatory syndrome children long COVID. Among these two, incidence COVID is higher its impact on population extensive, which focus us. However, due lack relevant studies limitations most studies, COVID-19 infection lag behind those adults, but they begun attract attention some clinicians researchers. We aim summarize current knowledge helping pediatricians researchers better understand providing guidance research clinical treatment it.

Language: Английский

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Cognition and Memory after Covid-19 in a Large Community Sample

New England Journal of Medicine, Journal Year: 2024, Volume and Issue: 390(21), P. 2034 - 2035

Published: June 5, 2024

Language: Английский

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