Time indices of pre-hospital EMS missions before and during the COVID-19 pandemic: a cross-sectional study in Iran

BMC Emergency Medicine, Journal Year: 2023, Volume and Issue: 23(1)

Published: Jan. 28, 2023

Abstract Background The COVID-19 pandemic resulted in many changes pre-hospital emergency medical services (EMS), including wearing full-body protective suits and well-fitted face masks, which can influence time indices the course of service delivery. present study aimed to compare EMS missions before during Iran. Methods This descriptive cross-sectional used census sampling select 17,860 calls that caused patient transfer facilities from March 2018 2021 then examined pandemic. data collection tool was a two-part checklist: patients' individual characteristics mission indices. were further analyzed using SPSS16 independent samples t-test. Results Out patients transferred by EMS, 11,773 cases (65.9%) male 6,087 (34.1%) female. most common reason for accidents (28.0%). Moreover, response ( P < 0.001), on-scene total run round trip 0.001) increased significantly Conclusions We concluded elevated following Updating information management systems, ambulances equipment, as well holding training courses personnel could effectively enhance missions.

Language: Английский

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Do Statins Affect Viral Infections Encountered by International Travelers?

Tropical Medicine and Infectious Disease, Journal Year: 2025, Volume and Issue: 10(3), P. 73 - 73

Published: March 11, 2025

Statins are among the most frequently prescribed medications. In addition to their well-established effectiveness in lowering total cholesterol, LDL, and triglycerides, statins have been described immunomodulatory anti-inflammatory properties associated with improved endothelial functions. Given common use of statins, we sought evaluate effect on some viral infections encountered by residents tropical areas or international travelers. A literature search was performed PubMED/MEDLINE focusing keywords that included viruses interest, including SARS-CoV-2, influenza, yellow fever, dengue, Zika, tick-borne encephalitis, hemorrhagic fever viruses, hepatitis A, norovirus, B, C, measles, herpesviruses; findings were synthesized for each virus into a summary. The effects vary depending specific virus. While studies indicate potential benefits chronic HBV HCV infections, evidence regarding SARS-CoV-2 influenza remains inconclusive due mixed from observational randomized controlled trials. role other is largely unexplored, preclinical data available only few viruses. conflicting evidence, further prospective trials warranted elucidate statins’ particularly modulating inflammation, dysfunction, immune responses. Future research should aim define optimal patient populations, target statin types, treatment durations may confer infections.

Language: Английский

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The impact of statin therapy on in‐hospital prognosis and endothelial function of patients at high‐to‐very high cardiovascular risk admitted for COVID‐19

Journal of Medical Virology, Journal Year: 2023, Volume and Issue: 95(3)

Published: March 1, 2023

Abstract Statins may protect against adverse outcomes from Coronavirus disease 2019 (COVID‐19) through their pleiotropic effects. Endothelial dysfunction seems to be implicated in the pathophysiology of COVID‐19, and can attenuated by statins. This study assessed role preadmission statin therapy its interaction with endothelial function, measured using flow‐mediated dilation (FMD) at hospital admission, predicting in‐hospital among patients COVID‐19 having high‐to‐very high cardiovascular (CV) risk. We conducted a retrospective cohort hospitalized CV risk, including subgroup who underwent FMD assessment. Among 342 patients, 119 (35%) were treated statins baseline. Preadmission was independently associated 75% risk reduction intensive care unit admission/in‐hospital death (adjusted hazard ratio 0.252, 95% confidence interval 0.122−0.521, p < 0.001). In an assessment (245 40% statin‐treated), higher values ( β = 0.159, 0.013). However, × not F 0.002, 0.960). is better independent endothelium‐protective effects these drugs.

Language: Английский

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Gastroesophageal Reflux in Lockdown

Future Science OA, Journal Year: 2023, Volume and Issue: 9(6)

Published: May 8, 2023

This study examines the changes in gastroesophageal reflux disease (GERD) symptom frequency among patients with GERD throughout COVID-19 pandemic.A structured questionnaire was distributed 198 patients. The consisted of a demographic characteristic assessment, GerdQ questionnaire, and index (RSI) questionnaire.A statistically significant increase score identified participants during pandemic (t = 7.055, df 209, p < 0.001), who had experienced an positive predictors decrease negative GERD. its related lockdown countermeasures may have led to exacerbating worsening symptoms.There is lack decisive research into impacts on We investigated symptomatic Jordan cross-sectional involving A number GERD, In addition, itself were also found increased pandemic, struggling sleep or attain additional medication treat their condition.

Language: Английский

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Recent Advancements on Long COVID in China: A Narrative Review

International Journal of General Medicine, Journal Year: 2023, Volume and Issue: Volume 16, P. 2585 - 2593

Published: June 1, 2023

Abstract: The COVID-19 pandemic is a huge public health crisis in the 21st century. In addition to acute symptoms, considerable proportion of patients worldwide have suffered from post-COVID-19 syndrome, commonly known as Long COVID. impact COVID on individual and burden cannot be ignored. According recent researches, has been affecting multiple organ systems throughout body, with respiratory, mental, nervous digestive symptoms often seen Chinese population. Clinical studies proved that were alleviated by variety treatments, such physical therapy, rehabilitation training, psychological support, behavioral cognitive stem cell etc. Based current clinical evidence, it recommended strengthen scientific research actively carry out early monitoring intervention future, so effectively prevent long-term disease economic pressure. Keywords: COVID, post-COVID conditions, China, characteristics, management strategies

Language: Английский

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COPD Pathogenesis and Alterations in the Oral, Lung, and Gut Microbiomes

Microbiology Research, Journal Year: 2024, Volume and Issue: 15(3), P. 1605 - 1615

Published: Aug. 20, 2024

Chronic obstructive pulmonary disease (COPD) is a respiratory and systemic affecting more than 300 million people globally every year, it also becomes substantial economic burden. COPD commonly comorbid with various underlying diseases such as cancer, cardiovascular diseases, cerebrovascular diabetes mellitus, osteoporosis, etc. It has been shown that statins can improve significant decline in function among patients due to their pleiomorphic effect. Some systematic reviews reported reduced the risk of COPD-related events cancer events, eventually resulting favorable outcomes for non-statin user patients. However, physiological mechanism still elucidated. Recently, influence gut microbial composition increased relative abundance Akkermansia muciniphila Faecalibacterium prausnitzii act effects anti-inflammatory anti-cancer through modulating dysbiosis. We described this review focus on whether be useful preventive option COPD.

Language: Английский

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The Early Warning Mechanism of Public Health Emergencies Through Whistleblowing: A Perspective Based on Considering the Uncertainty of Risk Perception

Risk Management and Healthcare Policy, Journal Year: 2023, Volume and Issue: Volume 16, P. 503 - 523

Published: March 1, 2023

Purpose: During the early warning period of public health emergencies, information released by whistleblowers on risk posed given event can reduce uncertainty in public's perception and help governments take timely actions to contain large-scale dissemination risk. The purpose this study is give full play draw attention events, forming a pluralistic model governance during emergencies. Methods: We construct an evolutionary game emergencies through whistleblowing that involves government, whistleblowers, public, discussing mechanism interaction between these subjects under perception. Furthermore, we use numerical simulations analyze influence changes relevant parameters trajectory subjects' behaviors. Results: results research are obtained simulation model. show cooperation with government encourages latter positive guidance strategy. Increasing reward for within acceptable cost, strengthening propaganda higher level will promote whistleblowers' vocalization actively. When government's lower, choose negative improvement If there no mandatory from at point, prone passively cooperating owing lack risk-related information. Conclusion: Establishing important containing Building daily work improve effectiveness enhance better when arise. Keywords: whistleblowing, prevention, perception,

Language: Английский

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Prevalence of gastro-intestinal Symptoms Among COVID-19 Patients and the Association With Disease Clinical Outcomes

Future Science OA, Journal Year: 2023, Volume and Issue: 9(5)

Published: April 21, 2023

This study examined the various manifestations of COVID-19 in people's gastro-intestinal system and how involvement relates to progression outcome disease.A questionnaire survey was used collect data from 561 patients between February 6 April 2022. Laboratory clinical outcomes were obtained patients' medical records.39.9% presented symptoms, mainly loss appetite, nausea, vomiting diarrhea. Gastro-intestinal symptoms not linked poorer such as mortality, ICU admission or length hospital stays.gastro-intestinal common among may manifest with respiratory symptoms. We recommended clinicians watch out for related infection.COVID-19 affects system. However, it has been previously reported that disease can impact other organ systems, particularly A prospective descriptive design which involved performed identify influenced disease. Almost 40% presence admission, stays increased mechanical intubation patients.

Language: Английский

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Prior Statin vs In-Hospital Statin Usage in Severe COVID-19: Review and Meta-Analysis

Current Problems in Cardiology, Journal Year: 2023, Volume and Issue: 48(9), P. 101810 - 101810

Published: May 20, 2023

Language: Английский

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Clinical Practice and Effectiveness Analysis of the Management of Corona Virus Disease 2019 Infected at Shanghai Fangcang Shelter Hospital: A Descriptive Study

Risk Management and Healthcare Policy, Journal Year: 2023, Volume and Issue: Volume 16, P. 337 - 346

Published: March 1, 2023

The Fangcang shelter hospital has gradually become the primary management mode in China's fight against this Corona Virus Disease 2019 (COVID-19) 2020. In early 2022, model was successfully applied to new outbreak of COVID-19 Shanghai also. Although hospitals are no longer prevailing prevention COVID-19, experience makeshift is worthy reference for public health.The authors conducted a descriptive statistical analysis Hall 6-2 National Convention and Exhibition Center hospital. whole hall managed by one hospital, inclusion third-party personnel alleviated shortage medical human resources. Through practice, procedure treating batch infected people introduced.By optimizing ward management, 72 on-duty doctors, 360 nurses, 3 sense-control administrators, 15 administrators cured 18,574 40 days, created record doctor managing 700 without compromising quality treatment. There have been deaths complaints from located hospital.Compared with previous data, provides infectious diseases health.

Language: Английский

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