Use of Medicinal Plants in the Process of Wound Healing: A Literature Review

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(3), P. 303 - 303

Published: Feb. 27, 2024

The literature on the use of medicinal plants in wound healing was comprehensively searched to obtain and assess data. data were procured via clinical studies that utilized their compounds vitro vivo for healing. This review collected from electronic databases, including Google Scholar, PubMed, Science Direct, Web Science, SciFinder, Thesis, Scopus, using search terms “natural products”, “wound healing”, compounds”, along with keywords “plants”, “extracts”, “phytochemicals”. Results last decade reveal a total 62 families 109 genera plants, have been studied experimentally both clinically found effectively promote activity is related presence secondary metabolites such as flavonoids, alkaloids, saponins, tannins, terpenoids, phenolic compounds, which act at different stages through mechanisms exert anti-inflammatory, antimicrobial, antioxidant effects, confirming could be an adequate alternative current conventional practices treating wounds.

Language: Английский

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Dynamic analysis of growth characteristics, secondary metabolites accumulation, and an in-depth understanding of anthraquinones biosynthesis in Rubia cordifolia Linn.

Frontiers in Plant Science, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 7, 2025

Rubia cordifolia is a well-known plant used in oriental medicine plant, and also serves as the primary traditional source of red dyestuffs. With current depletion natural resources R. cordifolia, it critical to conduct cultivation studies on cordifolia. Here, we report dynamic growth characteristics secondary metabolite accumulation cultivated well discovery important genes involved anthraquinone biosynthesis. The results showed that grows better sunny environments than shaded environments, its triennials biennials, base biomass concentration components purpurin mollugin. mollugin content suggested 30 June 15 October fair window for harvesting possibility specific transition connection during biosynthesis process. Furthermore, sequenced using SMRT technology first time obtained 45,925 full-length transcripts, 564 alternative splicing events, 3182 transcription factors, 6454 SSRs, 6361 lncRNAs. We hypothesized an biosynthetic pathway found 280 transcripts may be In addition, RT-qPCR was detect relative expression levels 12 candidate ungenes above- underground parts Above all, our findings have crucial implications field management provide useful genetic information clarifying potential

Language: Английский

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Anthraquinone Production from Cell and Organ Cultures of Rubia Species: An Overview

Metabolites, Journal Year: 2022, Volume and Issue: 13(1), P. 39 - 39

Published: Dec. 26, 2022

The Rubia genus includes major groups of medicinal plants such as cordifolia, tinctorum, and akane. They contain anthraquinones (AQs), particularly alizarin purpurin, which have pharmacological effects that are anti-inflammatory, antioxidant, anticancer, hemostatic, antibacterial, more. Alizarin purpurin been utilized natural dyes for cotton, silk, wool fabrics since the dawn time. These substances used in cosmetics food industries to color products. amount AQs different species is minimal. In order produce these compounds, researchers established cell organ cultures. Investigations conducted into numerous chemical physical parameters affect biomass accumulation secondary metabolites a cell, callus, hairy root, adventitious root suspension This article offers techniques approaches from species. Additionally, it has emphasized cells can be grown bioreactor cultures AQs.

Language: Английский

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Bigel Formulations of Nanoencapsulated St. John’s Wort Extract—An Approach for Enhanced Wound Healing

Gels, Journal Year: 2023, Volume and Issue: 9(5), P. 360 - 360

Published: April 25, 2023

This study aimed to develop a semisolid vehicle for topical delivery of nanoencapsulated St. John’s wort (SJW) extract, rich in hyperforin (HP), and explore its wound-healing potential. Four nanostructured lipid carriers (NLCs) were obtained: blank HP-rich SJW extract-loaded (HP-NLC). They comprised glyceryl behenate (GB) as solid lipid, almond oil (AO), or borage (BO) representing the liquid along with polyoxyethylene (20) sorbitan monooleate (PSMO) (SMO) surfactants. The dispersions demonstrated anisometric nanoscale particles acceptable size distribution disrupted crystalline structure, providing entrapment capacity higher than 70%. carrier exhibiting preferable characteristics (HP-NLC2) was gelled Poloxamer 407 (PM407) serve hydrophilic phase bigel, which combination BO monostearate (SMS) organogel added. eight prepared bigels different proportions (blank nanodispersion-loaded) characterized rheologically texturally investigate impact hydrogel-to-oleogel ratio. therapeutic potential superior formulation (HP-NLC-BG2) evaluated vivo on Wistar male rats through tensile strength test primary-closed incised wound. Compared commercial herbal control group, highest tear resistance (7.764 ± 0.13 N) achieved by HP-NLC-BG2, proving outstanding effect.

Language: Английский

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Prediction of suitable planting areas of Rubia cordifolia in China based on a species distribution model and analysis of specific secondary metabolites

Industrial Crops and Products, Journal Year: 2023, Volume and Issue: 206, P. 117651 - 117651

Published: Oct. 18, 2023

Language: Английский

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Enhanced resistance of Vigna unguiculata to Fusarium oxysporum via Rubia cordifolia extract and growth-promoting endophytic Bacillus amyloliquefaciens DW6

European Journal of Plant Pathology, Journal Year: 2024, Volume and Issue: 170(3), P. 567 - 591

Published: Aug. 18, 2024

Language: Английский

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Natural pigments as multifunctional additives in contact lenses

Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113748 - 113748

Published: Feb. 1, 2025

Language: Английский

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Biogenic synthesis of metal oxide nanoparticles for the elicitation of secondary metabolites in the in vitro propagated plantlets of Rubia cordifolia L.

Plant Cell Tissue and Organ Culture (PCTOC), Journal Year: 2025, Volume and Issue: 160(3)

Published: Feb. 25, 2025

Language: Английский

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Ancient Wisdom of <i>Ayurveda</i>: The Anti-inflammatory Benefits of Herbs for Managing Mastitis in Dairy Animals in South Asia

Journal of Natural Remedies, Journal Year: 2025, Volume and Issue: unknown, P. 257 - 277

Published: Feb. 28, 2025

Mastitis, characterized by mammary gland inflammation due to microorganisms, significantly reduces dairy animal productivity up 70%. Clinical mastitis prevalence stands at 11%, with sub-clinical cases a staggering 77%, highlighting its substantial impact on milk yield. Given the escalating concern of antibiotic resistance, exploring alternative therapies for treatment, particularly herbal remedies from Ayurveda and Ethno-veterinary practices, is imperative. Literature herbs used in bovine within South Asian countries was meticulously gathered diverse sources, including books electronic databases like Web Science, PubMed, ScienceDirect, Google Scholar domestic literature. A comprehensive review identified 83 documented anti-inflammatory properties, assessing their potential treating animals. Constituents such as flavonoids, polyphenols, terpenoids, alkaloids, vitamins, minerals were scrutinised effects. Additionally, formulations mentioned ancient Indian veterinary Sanskrit manuscript ‘Ashvavaidyakam’ have been revealed verify ability mitigate associated future. This synthesizes traditional wisdom contemporary scientific evidence advocate further research dialogue. It underscores develop effective sustainable control strategies practices. Plant-based are highlighted reduce production losses costs, thereby proving therapeutic significance farmers. The integration knowledge modern findings presents promising avenues addressing Embracing offers not only economic benefits but also contributes sustainability farming practices Asia. Further this area crucial harness full management. Major Findings: total properties treatment. Active constituents terpenoids alkaloids exhibit significant potential. Herbal Ashvavaidyakam offer leads management

Language: Английский

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Rubia cordifolia Linn.: Isolation, Molecular Docking and BRAC1/PKD1 Gene Targeting for Polycystic Ovary Syndrome in Rats

Journal of Reproductive Immunology, Journal Year: 2025, Volume and Issue: unknown, P. 104532 - 104532

Published: April 1, 2025

Language: Английский

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