Biological evaluation of nutritional traditional fruit Mangifera camptosperma against diabetes and hyperlipidemia DOI Creative Commons
Bichitrananda Tripathy, Nityananda Sahoo, Sudhir Kumar Sahoo

et al.

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2024, Volume and Issue: 11, P. 100436 - 100436

Published: May 10, 2024

The objective of the study was to determine antidiabetic and antihyperlipidemic effects Mangifera camptosperma leaves extract using streptozotocin-induced animal model. M. extracted with hydroethanolic (50:50) solvent soxhlet apparatus. Traditional Chinese medicine (TCM) is often given as an adjuvant alleviate diabetic symptoms. plant extracts were used presence phytochemicals present in them different tests. Diabetes induced on animals streptozotocin (STZ) 65 mg/kg through intra-peritoneal route. Oral administration at doses 200 400 assess its effects. phytochemical analysis showing carbohydrates, alkaloids, tannins, glycosides, flavonoids. control group had blood glucose levels 102 126 mg/kg, respectively, after receiving test medication, but rats treated showed a substantial decrease 90.11 ± 5.71 (200 mg/kg) 82.12 3.99 (400 mg/kg). If compared group, for 21 days resulted (p<0.05) serum total cholesterol (106.12 5.94 mg/dL) triglyceride (83.11 4.04 mg/dL), well increase HDL (36.15 3.04 mg/dL). This found that while administered rats, lowered improved lipid profiles. It can be concluded from may useful treating hyperlipidemic type-2 diabetes alternative medicine.

Language: Английский

Targeting Metabolic Diseases with Celastrol: A Comprehensive Review of Anti-Inflammatory Mechanisms and Therapeutic Potential DOI

Xiaojuan Wang,

Mohamad Hafizi Abu Bakar,

Liqun Song

et al.

Journal of Ethnopharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 119560 - 119560

Published: Feb. 1, 2025

Language: Английский

Citations

0
Dilemmas in Elderly Diabetes and Clinical Practice Involving Traditional Chinese Medicine DOI Creative Commons
Chongxiang Xue, Ying Chen,

Yuntian Bi

et al.

Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(7), P. 953 - 953

Published: July 16, 2024

Diabetes is a widespread chronic disease that occurs mainly in the elderly population. Due to difference pathophysiology between and young patients, current clinical practice treat patients with anti-diabetes medications still faces some challenges dilemmas, such as urgent need for early diagnosis prevention, an imbalance restricted dietary intake risk of undernutrition. Traditional Chinese medicine (TCM) offers various treatment regimens are actively utilized field diabetes management. Through multiple targets pathways, TCM formulas, medicinal herbs, active natural products enhance efficacy prevention control measures, simplify complex medication management, improve common symptoms diabetic complications people. Historically, have played key role material composition analysis mechanism interpretation enable drug discovery. However, there been few conclusions on this topic. This review summarizes development management people, existing evidence-based practices, prospects future development.

Language: Английский

Citations

1
Differential mechanisms of Liuwei Dihuang pill-derived formulas in treating diabetic nephropathy based on in vitro experiments and transcriptomic analysis DOI
Shijie Bi,

Anlei Yuan,

Zhenzhen Xu

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: unknown, P. 105732 - 105732

Published: Dec. 1, 2024

Language: Английский

Citations

1
Biological evaluation of nutritional traditional fruit Mangifera camptosperma against diabetes and hyperlipidemia DOI Creative Commons
Bichitrananda Tripathy, Nityananda Sahoo, Sudhir Kumar Sahoo

et al.

Pharmacological Research - Modern Chinese Medicine, Journal Year: 2024, Volume and Issue: 11, P. 100436 - 100436

Published: May 10, 2024

The objective of the study was to determine antidiabetic and antihyperlipidemic effects Mangifera camptosperma leaves extract using streptozotocin-induced animal model. M. extracted with hydroethanolic (50:50) solvent soxhlet apparatus. Traditional Chinese medicine (TCM) is often given as an adjuvant alleviate diabetic symptoms. plant extracts were used presence phytochemicals present in them different tests. Diabetes induced on animals streptozotocin (STZ) 65 mg/kg through intra-peritoneal route. Oral administration at doses 200 400 assess its effects. phytochemical analysis showing carbohydrates, alkaloids, tannins, glycosides, flavonoids. control group had blood glucose levels 102 126 mg/kg, respectively, after receiving test medication, but rats treated showed a substantial decrease 90.11 ± 5.71 (200 mg/kg) 82.12 3.99 (400 mg/kg). If compared group, for 21 days resulted (p<0.05) serum total cholesterol (106.12 5.94 mg/dL) triglyceride (83.11 4.04 mg/dL), well increase HDL (36.15 3.04 mg/dL). This found that while administered rats, lowered improved lipid profiles. It can be concluded from may useful treating hyperlipidemic type-2 diabetes alternative medicine.

Language: Английский

Citations

0