Whole-Body Cryostimulation in Post-COVID Rehabilitation for Patients with Obesity: A Multidisciplinary Feasibility Study

Biomedicines, Journal Year: 2023, Volume and Issue: 11(11), P. 3092 - 3092

Published: Nov. 18, 2023

A post-COVID condition can reduce activity and quality of life, resulting in a significant socioeconomic health burden. Understanding its impact on patients' is important for the development personalized rehabilitation interventions. An independent association between obesity was found because complications comorbidities.Sixteen patients with symptoms (i.e., dyspnea, pain, poor sleep quality, muscle fatigue), admitted to Istituto Auxologico Italiano, Piancavallo (VB), Italy, were recruited four-week program including conventional exercise therapy, nutritional intervention, psychological support whole-body cryostimulation (WBC).All participants attended all sessions program. Anthropometric data showed statistically changes weight, waist circumference body mass index. Biochemical analyses reductions lipid inflammatory profiles. There improvement physical performance, reduction pain well-being.A multidisciplinary protocol WBC, designed condition, safe feasible. The overall improvements demonstrate that effective post COVID suggest use WBC could play role as booster programs.

Language: Английский

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Obesity as a Risk Factor for Complications and Mortality in Individuals with SARS-CoV-2: A Systematic Review

Nutrients, Journal Year: 2024, Volume and Issue: 16(4), P. 543 - 543

Published: Feb. 16, 2024

This systematic review aimed to analyze the available studies that identified overweight and/or obesity as a risk factor for mortality, use of respiratory support, and changes in biochemical markers adults hospitalized with SARS-CoV-2. The PubMed, Web Science, Scopus databases were searched using PRISMA guidelines until January 2024. protocol was registered PROSPERO (code: CRD42024501551). Of 473 articles, only 8 met inclusion criteria (e.g., adult individuals aged 18 or over diagnosed COVID-19 obesity). In addition, Downs Black tool used assess quality studies. analyzed totaled 9782 COVID-19, indicating are present more than half adults. Diseases such diabetes mellitus hypertension prevalent obesity. also highlighted higher incidence support is related hospitalization intensive care units have mortality from COVID-19. Biochemical procalcitinin, C-reactive protein, interleukin-6 associated severity infection. exposed worse disease, well need care, essential blood markers.

Language: Английский

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Obesity-compromised immunity in post-COVID-19 condition: a critical control point of chronicity

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Aug. 12, 2024

Post-COVID-19 condition is recognized as a multifactorial disorder, with persistent presence of viral antigens, discordant immunity, delayed clearance, and chronic inflammation. Obesity has emerged an independent risk factor for both SARS-CoV-2 infection its subsequent sequelae. In this study, we aimed to predict the molecular mechanisms linking obesity post-COVID-19 distress. Viral antigen-exposed adipose tissues display remarkable levels receptors, facilitating entry, deposition, release inflammatory mediators cells in patients. Subsequently, obesity-associated insults are predicted disturb cellular humoral immunity by triggering abnormal cell differentiation lymphocyte exhaustion. particular, decline antibody titers T-cell exhaustion due inflammation may account virus clearance activation responses. Taken together, defective critical control point intervention against progression, particularly subjects metabolic

Language: Английский

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An Analysis Between Body Composition and Vertigo Post-Coronavirus Disease 2019 Patients

International Archives of Otorhinolaryngology, Journal Year: 2025, Volume and Issue: 29(02), P. 001 - 008

Published: April 1, 2025

Abstract Introduction An association between the sensation of vertigo, and body composition has not been investigated in post-coronavirus disease 2019 (COVID-19) patients. Objective To evaluate probable vertigo composition—as amount fat, bone, muscle—in post-COVID-19 Methods Cross-sectional study with a sample patients who responded to visual analog scale (VAS) Dizziness Handicap Inventory (DHI). Clinical assessment electrical bioimpedance were used determine composition. Results There 105 participants evaluated, 61% (n = 64) whom male, aged 49.5 ± 11.7 years, an average height 165.6 19.9 cm, weight 87.6 20 kg, mass index (BMI) 31.1 5.4 kg/m. The prevalence self-reported was 51.4% 54); these, 11.4% 12) related before diagnosis COVID-19, 40% 42) during or after COVID-19. Furthermore, 37.2% 39) reported that persisted medical discharge. In comparative analysis, data showed significant difference groups without for (p 0.001), 0.006), water lean 0.002), fat-free musculoskeletal 0.001). Conclusion complaint patients, suggesting these aspects should be considered when assessing can contribute construction knowledge about long COVID.

Language: Английский

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Effects of a Multi-Professional Intervention on Mental Health of Middle-Aged Overweight Survivors of COVID-19: A Clinical Trial

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(5), P. 4132 - 4132

Published: Feb. 25, 2023

The present study aimed to investigate the effects of a multi-professional intervention model on mental health middle-aged, overweight survivors COVID-19. A clinical trial with parallel groups and repeated measures was conducted. For eight weeks, interventions were conducted (psychoeducation, nutritional intervention, physical exercises). One hundred thirty-five or obese patients aged 46.46 ± 12.77 years distributed into four experimental groups: mild, moderate, severe COVID, control group. instruments used: continuum-MHC, revised impact scale–IES-r, generalized anxiety disorder-GAD-7, Patient questionnaire PHQ-9, before after weeks. main results indicated only time effect, significant increase in global MHC scores, emotional well-being, social psychological as well detected reduction IES-R intrusion, avoidance, hyperarousal, addition GAD-7 PHQ-9 scores (p < 0.05). In conclusion, it possible identify those psychoeducational that effectively reduced anxiety, depression, post-traumatic stress symptoms post-COVID-19 patients, regardless symptomatology, However, moderate need be monitored continuously since these did not follow response pattern mild groups.

Language: Английский

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Effects of a multi-professional intervention on body composition, physical fitness and biochemical markers in overweight COVID-19 survivors: a clinical trial

Frontiers in Physiology, Journal Year: 2023, Volume and Issue: 14

Published: Aug. 28, 2023

Introduction: The sequelae post-COVID can affect different systems. In this sense, considering the multi-factorial etiology of COVID-19, multi-professional interventions could be a relevant strategy for recovery health indicators. Objective: This study aimed to investigate effects intervention on body composition, physical fitness, and biomarkers in overweight COVID-19 survivors with symptomatology. Methodology: A non-randomized parallel group included 69 volunteers (BMI ≥25 kg/m2), divided into three groups according SARS CoV-2 symptomatology, but only 35 finished longitudinal protocol [control (n = 11); moderate 17) severe 7)]. were submitted program (nutritional intervention, psychoeducation, exercise intervention) 8 weeks, underwent composition assessments (primary outcome) biochemical tests (secondary pre- post-intervention. was registered Clinical Trials Registration Platform number: RBR-4mxg57b local research ethics committee under 4,546,726/2021. Results: After 8-week following results observed group: improved dynamic strength lower- (p 0.003), upper-limbs 0.008), maximal isometric lumbar-traction 0.04), flexibility 0.0006), albumin 0.0005), as well reduction C reactive protein (CRP) 0.003) fasting glucose 0.001); an improvement lower-body 0.001), higher values 0.005) HDL-c 0.002), lower CRP 0.05), control sit-up repetitions 0.01), 0.001) total cholesterol 0.04) identified. All experimental reduced triglycerides after < 0.05). Conclusion: Finally, weeks multiprofessional efficient tool reversing inflammatory process promoting improvements daily activities quality life, although it is believed that needs longer improve Trial Registration: https://ensaiosclinicos.gov.br/, identifier: RBR-4mxg57b.

Language: Английский

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Body composition and cardiorespiratory fitness of overweight COVID-19 survivors in different severity degrees: a cohort study

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Oct. 17, 2023

COVID-19 sequelae are varied, and whether they temporary or permanent is still unknown. Identifying these may guide therapeutic strategies to improve individuals' recovery. This prospective cohort aimed assess body composition, cardiopulmonary fitness, long-term symptoms of overweight individuals affected by COVID-19. Participants (n = 90) were divided into three groups according the severity acute COVID-19: mild (no hospitalization), moderate (hospitalization, without oxygen support), severe/critical cases (hospitalized in Intensive Care Unit). We assessed composition with a tetrapolar multifrequency bioimpedance, hemodynamic variables (heart rate, blood pressure, peripheral saturation-SpO2) at rest, Bruce test direct gas exchange. Two assessments one-year interval performed. The most prevalent memory deficit (66.7%), lack concentration (51.7%), fatigue (65.6%), dyspnea (40%). presented time effect an increase distance walked after 1 year just for group (p < 0.05). SpO2 was significantly lower up 5 min when compared group, diastolic pressure end higher 0.05; all comparisons). A observed increased lean mass, skeletal muscle fat-free mass Cardiopulmonary fitness parameters did not differ among groups, except respiratory quotient values itself year. All patients might present sequelae, regardless disease severity. Reassessing identifying essential perform more precise health promotion interventions.

Language: Английский

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Impact of COVID-19 Infection on Cardiorespiratory Fitness, Sleep, and Psychology of Endurance Athletes—CAESAR Study

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(8), P. 3002 - 3002

Published: April 20, 2023

COVID-19 has a deteriorating impact on health which is especially important for endurance athletes (EAs) who need to maintain continuity of training. The illness affects sleep and psychology, influence sport performance. aims this study were: (1) assess the consequences mild psychology (2) cardiopulmonary exercise test (CPET) results. A total 49 EAs (males = 43, 87.76%; females 6, 12.24%; age 39.9 ± 7.8 years; height 178.4 6.8 cm; weight 76.3 10.4 kg; BMI 24.0 2.6 kg·m−2) underwent maximal cycling or running CPET pre- post-COVID-19 completed an original survey. Exercise performance deteriorated after (maximal oxygen uptake, VO2max 47.81 7.81 vs. 44.97 7.00 mL·kg·min−1 post-infection, respectively; p < 0.001). Waking up at night affected heart rate (HR) respiratory compensation point (RCP) (p 0.028). Sleep time influenced pulmonary ventilation 0.013), breathing frequency 0.010), blood lactate concentration (Lac) 0.013) RCP. power/speed 0.046) HR 0.070) were linked quality sleep. Stress management relaxation techniques with 0.046), 0.033), Lac 0.045). Cardiorespiratory fitness was correlated psychological indices. Medical professionals should encourage proper mental infection facilitate recovery.

Language: Английский

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Cardiopulmonary Profiling of Athletes with Post-Exertional Malaise after COVID-19 Infection—A Single-Center Experience

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(13), P. 4348 - 4348

Published: June 28, 2023

(1) Background: Cardiopulmonary exercise testing (CPET) has been suggested by the European Society of Cardiology (ESC) for assessing limitations apparently healthy individuals, but data on elite athletes regarding this test are scarce. (2) Methods: We analyzed CPET in (n = 43, 21.9 ± 3.7 years) and recreational 40, 34.7 13.0 with persistent subjective intolerance post-exertional malaise (PEM) after COVID-19 infection. The primary outcome was point prevalence adequate cardiopulmonary response (ACPR), defined presence all following ESC criteria individuals: >100% predicted peak oxygen consumption (predVO2peak), VE/VCO2 < 30, (3) no oscillatory ventilation (EOV), (4) heart rate recovery ≥12 beats/minute 1 min termination (HRR1). Results: ACPR occurred more frequently than (70.0% vs. 39.5%; p 0.005), mainly driven lower (<30: 97.7% 65%, 0.001). Elite (11.6%) (22.5%) showing a plateau O2 pulse did not display ACPR. Conclusions: observed PEM. In particular, perturbed plateauing suitable quantifying may identify high-risk population long-COVID-19 syndrome who require their training intensities to be adapted.

Language: Английский

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An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19

Expert Review of Clinical Immunology, Journal Year: 2023, Volume and Issue: 19(7), P. 693 - 697

Published: May 16, 2023

KEYWORDS: Exercise testingcardiorespiratory-immunological fitnessPost-Acute Sequelae of COVIDMyalgic-Encephalopathy/Chronic Fatigue Syndromepost-exertional malaiseimmune system failure

Language: Английский

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