Review on analytical technologies and applications in metabolomics DOI Open Access
Xin Meng, Yan Liu,

SHUJUN XU

et al.

Biocell, Journal Year: 2024, Volume and Issue: 48(1), P. 65 - 78

Published: Jan. 1, 2024

Over the past decade, swift advancement of metabolomics can be credited to significant progress in technologies such as mass spectrometry, nuclear magnetic resonance, and multivariate statistics. Currently, garners widespread application across diverse fields including drug research development, early disease detection, toxicology, food nutrition science, biology, prescription, chinmedomics, among others. Metabolomics serves an effective characterization technique, offering insights into physiological process alterations in vivo. These changes may result from various exogenous factors like environmental conditions, stress, medications, well endogenous elements genetic protein-based influences. The potential scientific outcomes gleaned these have catalyzed formulation innovative methods, poised further broaden scope this domain. Today, has evolved a valuable widely accepted instrument life sciences. However, comprehensive reviews focusing on sample preparation analytical methodologies employed within sciences are surprisingly scant. This review aims fill that gap, providing overview current trends recent advancements metabolomics. Particular emphasis is placed preparation, sophisticated techniques, their applications science research.

Language: Английский

Advancing athletic assessment by integrating conventional methods with cutting-edge biomedical technologies for comprehensive performance, wellness, and longevity insights DOI Creative Commons
Marios Spanakis,

Persefoni Fragkiadaki,

Elisavet Renieri

et al.

Frontiers in Sports and Active Living, Journal Year: 2024, Volume and Issue: 5

Published: Jan. 8, 2024

In modern athlete assessment, the integration of conventional biochemical and ergophysiologic monitoring with innovative methods like telomere analysis, genotyping/phenotypic profiling, metabolomics has potential to offer a comprehensive understanding athletes' performance longevity. Telomeres provide insights into cellular functioning, aging, adaptation elucidate effects training on health. Genotype/phenotype analysis explores genetic variations associated athletic performance, injury predisposition, recovery needs, enabling personalization plans interventions. Metabolomics especially focusing low-molecular weight metabolites, reveal metabolic pathways responses exercise. Biochemical tests assess key biomarkers related energy metabolism, inflammation, recovery. Essential elements depict micronutrient status individual, which is critical for optimal performance. Echocardiography provides detailed cardiac structure function, while burnout testing evaluates psychological stress, fatigue, readiness By integrating this scientific battery, multidimensional health can be achieved, leading personalized interventions in training, nutrition, supplementation, prevention, mental wellness support. This scientifically rigorous approach hereby presented holds significant improving longevity through evidence-based, individualized interventions, contributing advances field sports optimization.

Language: Английский

Citations

2

Review on analytical technologies and applications in metabolomics DOI Open Access
Xin Meng, Yan Liu,

SHUJUN XU

et al.

Biocell, Journal Year: 2024, Volume and Issue: 48(1), P. 65 - 78

Published: Jan. 1, 2024

Over the past decade, swift advancement of metabolomics can be credited to significant progress in technologies such as mass spectrometry, nuclear magnetic resonance, and multivariate statistics. Currently, garners widespread application across diverse fields including drug research development, early disease detection, toxicology, food nutrition science, biology, prescription, chinmedomics, among others. Metabolomics serves an effective characterization technique, offering insights into physiological process alterations in vivo. These changes may result from various exogenous factors like environmental conditions, stress, medications, well endogenous elements genetic protein-based influences. The potential scientific outcomes gleaned these have catalyzed formulation innovative methods, poised further broaden scope this domain. Today, has evolved a valuable widely accepted instrument life sciences. However, comprehensive reviews focusing on sample preparation analytical methodologies employed within sciences are surprisingly scant. This review aims fill that gap, providing overview current trends recent advancements metabolomics. Particular emphasis is placed preparation, sophisticated techniques, their applications science research.

Language: Английский

Citations

1