Applied Phycology,
Journal Year:
2024,
Volume and Issue:
5(1), P. 37 - 53
Published: Aug. 1, 2024
Marine
microalgae
offer
significant
potential
as
sustainably
cultivable
microorganisms
for
the
biorefining
of
a
diverse
array
functional
metabolites.
In
this
study,
three
species
marine
microalgae,
Tetraselmis
chuii
Butcher
CCAP
66/21B
(Chlorophyte),
Phaeodactylum
tricornutum
Bohlin
1052/1
(Diatom)
and
Amphidinium
carterae
Hulburt
1102/8
(Dinoflagellate),
were
batch
cultivated
their
biomass
retrieved
analysis
in
terms
pigment
fatty
acid
composition
well
bioactivity
potential.
Sequential
solvent
maceration
returned
extracts
was
used
to
determine
antioxidant
capacity
assess
growth
inhibition
against
A549
(a
human
lung
carcinoma)
MCF-7
breast
cell
lines.
The
A.
showed
higher
(≤
33.5
μmol
Trolox
Equivalent
mg
Recovered
Dried
Material‒1)
compared
other
extracts.
No
major
cytotoxic
activity
nor
production
reactive
oxygen
observed
using
T.
P.
tricornutum.
However,
methanolic
extraction
inhibited
both
cells
(<
4%)
at
25,
50
100
µg
ml−1
concentrations,
determined
MTS
assay
AO/PI
staining.
Microalgal
metabolites
have
practical
applications
variety
industrial
sectors.
absence
toxicity
substantial
confirm
suitability
incorporation
into
animal
feeds
or
nutrition
supplements.
also
appears
be
promising
source
bioactives
that
can
further
valorized
via
multi-compound
biorefinery
pipelines.
Life,
Journal Year:
2025,
Volume and Issue:
15(2), P. 184 - 184
Published: Jan. 26, 2025
This
study
explores
the
mixotrophic
cultivation
of
Limnospira
platensis
using
dairy
byproducts,
specifically
scotta
whey
(SW),
buttermilk
wastewater
(BMW),
and
(DWW),
to
promote
biomass
production
enhance
composition
bioactive
compounds.
By
assessing
various
concentrations
(1%,
2%,
4%
v
v−1)
these
byproducts
in
a
modified
growth
medium,
this
aims
evaluate
their
effect
on
L.
growth,
phycocyanin
(C-PC)
content,
fatty
acid
methyl
ester
(FAME)
profiles.
The
results
show
that
optimal
was
achieved
with
2%
wastewater,
reaching
maximum
3.30
g
L−1
3.19
L−1,
respectively.
Mixotrophic
led
increased
C-PC
yields,
especially
treatments,
highlighting
potential
for
producing
valuable
pigments.
Additionally,
FAME
profiles
indicated
minimal
changes
compared
control,
oleic
γ-linolenic
acids
being
dominant
conditions.
These
findings
support
viability
utilizing
sustainable
cultivation,
contributing
circular
bioeconomy
while
compounds
nutritional
commercial
interest.
Frontiers in Sustainable Food Systems,
Journal Year:
2024,
Volume and Issue:
8
Published: Feb. 23, 2024
Microalgae
are
emerging
as
a
sustainable
source
of
bioproducts,
including
food,
animal
feed,
nutraceuticals,
and
biofuels.
This
review
emphasizes
the
need
to
carefully
select
suitable
species
highlights
importance
strain
optimization
enhance
feasibility
developing
algae
resource
for
food
biomaterial
production.
It
discusses
microalgal
bioprospecting
methods,
different
types
cultivation
systems,
biomass
yields,
using
wastewater.
The
paper
advances
in
artificial
intelligence
that
can
optimize
algal
productivity
overcome
limitations
faced
current
industries.
Additionally,
potential
UV
mutagenesis
combined
with
high-throughput
screening
is
examined
strategy
generating
improved
strains
without
introducing
foreign
genetic
material.
necessity
multifaceted
approach
enhanced
acknowledged.
provides
an
overview
recent
developments
crucial
commercial
success
In
recent
times,
there
has
been
a
revolutionary
surge
in
antioxidant
research,
with
focus
on
harnessing
microalgae
to
enhance
wellness
and
extend
human
longevity.
Microalgae,
diverse
group
of
unicellular
photosynthetic
organisms,
have
emerged
as
promising
sources
natural
antioxidants
due
their
ability
synthesize
various
bioactive
compounds,
including
carotenoids,
polyphenols,
tocopherols.
These
play
pivotal
role
scavenging
free
radicals
reducing
oxidative
stress,
known
contributors
aging
chronic
diseases.
This
review
provides
an
over-view
advancements
understanding
microalgae’s
potential,
covering
biochemical
composition,
extraction
techniques,
purification
methods.
Moreover,
it
delves
into
compelling
vitro
vivo
studies
showcasing
microalgae-derived
antioxidants’
protective
effects
against
damage,
inflammation,
cardiovascular
diseases,
neurodegenerative
disorders.
The
sustainable
cultivation
controlled
environments
further
supports
the
potential
for
large-scale
production
commercialization
compounds.
As
continue
revolutionize
they
hold
immense
promise
developing
novel
preventive
therapeutic
strategies
promote
health
wellbeing.
Aquaculture Reports,
Journal Year:
2023,
Volume and Issue:
32, P. 101727 - 101727
Published: Sept. 13, 2023
Spirulina
is
a
popular
edible
blue-green
alga
that
has
piqued
the
interest
of
aqua-feed
formulations
due
to
its
high
concentration
micronutrients,
macronutrients,
and
antioxidants.
To
investigate
impacts
natural
as
feed
additive
on
Stinging
catfish
(Heteropneustes
fossilis)
growth,
utilization,
hematology
serum
biochemistry,
gut
morphology,
well
disease
resistance
Aeromonas
hydrophila,
60-day
feeding
experiment
was
performed.
The
fish
(N
=
240),
with
an
initial
weight
4.23
±
0.50
g,
were
placed
in
12
aquaria
tanks
(100
L/
tank)
fed
twice
daily
until
they
satisfied.
Four
different
experimental
diets:
0%
(D0,
control
diet),
1%
(D1),
3%
(D2),
5%
(D3)
meal
used
fish.
This
study
found
diet
obtained
notably
higher
(p
<
0.05)
specific
growth
rate,
final
weight,
gain,
average
gain
than
other
supplemented
regimens.
Furthermore,
inclusion
diets
increased,
utilization
parameters
such
conversion
ratio
protein
efficiency
improved
remarkably
0.05).
Red
blood
cell,
white
lymphocytes,
neutrophil,
monocytes,
basophil,
hemoglobin,
red
cell
distribution
width-standard
deviation,
mean
corpuscular
hemoglobin
all
substantially
greater
diet-fed
basal
had
lower
total
protein,
globulin,
albumin
levels
glucose,
cholesterol,
triglyceride
those
test
diets.
Compared
groups,
light
microscopic
examination
intestinal
tissues
revealed
well-organized
enterocytes,
intact
epithelial
barrier,
abundant
goblet
cells,
lacking
luminal
debris,
exhibited
no
signs
inflammation
(edema).
significantly
affected
villi
height
width,
mucosa
crypt
depth,
villi,
lumen
area.
demonstrated
(68.57%)
A.
hydrophila
during
bacterial
challenge
trial.
Based
findings,
applying
powder
at
supplement
could
benefit
H.
fossilis
nutrient
performance,
health
status,
resistance.
Foods,
Journal Year:
2023,
Volume and Issue:
12(14), P. 2652 - 2652
Published: July 10, 2023
In
order
to
rapidly
screen
microalgae
species
as
feedstocks
for
antioxidants,
extracts
were
obtained
from
16
strains
(under
11
genera,
7
classes)
using
two
methods:
a
one-step
extraction
with
ethanol/water
and
three-step
fractionating
procedure
hexane,
ethylacetate,
water
successively.
Measuring
the
total
phenol
content
(TPC),
carotenoid
(TCC),
antioxidant
activity
of
extracts,
indicating
TPC
TCC,
played
an
important
role
in
determining
microalgae.
A
weighted
scoring
system
was
used
evaluate
activity,
scores
microalgal
samples
methods
calculated
same
system.
Among
investigated
microalgae,
Euglena
gracilis
SCSIO-46781
had
highest
score,
contributing
high
followed
by
Arthrospira
platensis
SCSIO-44012,
Nannochloropsis
sp.
SCSIO-45224,
Phaeodactylum
tricornutum
SCSIO-45120,
SCSIO-45006,
respectively.
Additionally,
above-mentioned
five
are
currently
being
applied
commercial
production,
this
could
be
effective
not
only
screening
but
also
species/strains
strong
adaptation
environmental
stress,
which
is
critical
trait
their
cultivation.
