Antioxidant properties and bioactivity of three marine microalgae on human cancer cell lines DOI Creative Commons
Helen Herbert, Rachel Parkes, Maria Elena Barone

et al.

Applied Phycology, Journal Year: 2024, Volume and Issue: 5(1), P. 37 - 53

Published: Aug. 1, 2024

Marine microalgae offer significant potential as sustainably cultivable microorganisms for the biorefining of a diverse array functional metabolites. In this study, three species marine microalgae, Tetraselmis chuii Butcher CCAP 66/21B (Chlorophyte), Phaeodactylum tricornutum Bohlin 1052/1 (Diatom) and Amphidinium carterae Hulburt 1102/8 (Dinoflagellate), were batch cultivated their biomass retrieved analysis in terms pigment fatty acid composition well bioactivity potential. Sequential solvent maceration returned extracts was used to determine antioxidant capacity assess growth inhibition against A549 (a human lung carcinoma) MCF-7 breast cell lines. The A. showed higher (≤ 33.5 μmol Trolox Equivalent mg Recovered Dried Material‒1) compared other extracts. No major cytotoxic activity nor production reactive oxygen observed using T. P. tricornutum. However, methanolic extraction inhibited both cells (< 4%) at 25, 50 100 µg ml−1 concentrations, determined MTS assay AO/PI staining. Microalgal metabolites have practical applications variety industrial sectors. absence toxicity substantial confirm suitability incorporation into animal feeds or nutrition supplements. also appears be promising source bioactives that can further valorized via multi-compound biorefinery pipelines.

Language: Английский

A critical review of characteristics of domestic wastewater and key treatment techniques in Chinese villages DOI
Jing Zhang, Yungeng Jiang, Heyu Zhang

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 927, P. 172155 - 172155

Published: April 2, 2024

Language: Английский

Citations

31

Dairy Wastewaters to Promote Mixotrophic Metabolism in Limnospira (Spirulina) platensis: Effect on Biomass Composition, Phycocyanin Content, and Fatty Acid Methyl Ester Profile DOI Creative Commons

Luca Baraldi,

Luca Usai,

Serenella Torre

et al.

Life, Journal Year: 2025, Volume and Issue: 15(2), P. 184 - 184

Published: Jan. 26, 2025

This study explores the mixotrophic cultivation of Limnospira platensis using dairy byproducts, specifically scotta whey (SW), buttermilk wastewater (BMW), and (DWW), to promote biomass production enhance composition bioactive compounds. By assessing various concentrations (1%, 2%, 4% v v−1) these byproducts in a modified growth medium, this aims evaluate their effect on L. growth, phycocyanin (C-PC) content, fatty acid methyl ester (FAME) profiles. The results show that optimal was achieved with 2% wastewater, reaching maximum 3.30 g L−1 3.19 L−1, respectively. Mixotrophic led increased C-PC yields, especially treatments, highlighting potential for producing valuable pigments. Additionally, FAME profiles indicated minimal changes compared control, oleic γ-linolenic acids being dominant conditions. These findings support viability utilizing sustainable cultivation, contributing circular bioeconomy while compounds nutritional commercial interest.

Language: Английский

Citations

3

Enhancing algal production strategies: strain selection, AI-informed cultivation, and mutagenesis DOI Creative Commons

Amnah Alzahmi,

Sarah Daakour,

David R. Nelson

et al.

Frontiers in Sustainable Food Systems, Journal Year: 2024, Volume and Issue: 8

Published: Feb. 23, 2024

Microalgae are emerging as a sustainable source of bioproducts, including food, animal feed, nutraceuticals, and biofuels. This review emphasizes the need to carefully select suitable species highlights importance strain optimization enhance feasibility developing algae resource for food biomaterial production. It discusses microalgal bioprospecting methods, different types cultivation systems, biomass yields, using wastewater. The paper advances in artificial intelligence that can optimize algal productivity overcome limitations faced current industries. Additionally, potential UV mutagenesis combined with high-throughput screening is examined strategy generating improved strains without introducing foreign genetic material. necessity multifaceted approach enhanced acknowledged. provides an overview recent developments crucial commercial success

Language: Английский

Citations

12

Antioxidants from microalgae and their potential impact on human well-being DOI Creative Commons
Leonel Pereira, João Cotas, Ana Valado

et al.

Published: May 31, 2024

In recent times, there has been a revolutionary surge in antioxidant research, with focus on harnessing microalgae to enhance wellness and extend human longevity. Microalgae, diverse group of unicellular photosynthetic organisms, have emerged as promising sources natural antioxidants due their ability synthesize various bioactive compounds, including carotenoids, polyphenols, tocopherols. These play pivotal role scavenging free radicals reducing oxidative stress, known contributors aging chronic diseases. This review provides an over-view advancements understanding microalgae’s potential, covering biochemical composition, extraction techniques, purification methods. Moreover, it delves into compelling vitro vivo studies showcasing microalgae-derived antioxidants’ protective effects against damage, inflammation, cardiovascular diseases, neurodegenerative disorders. The sustainable cultivation controlled environments further supports the potential for large-scale production commercialization compounds. As continue revolutionize they hold immense promise developing novel preventive therapeutic strategies promote health wellbeing.

Language: Английский

Citations

12

Effects of dietary supplementation of natural Spirulina on growth performance, hemato-biochemical indices, gut health, and disease resistance to Aeromonas hydrophila of Stinging catfish (Heteropneustes fossilis) fingerling DOI Creative Commons

Mobasshsirin Rahman,

Md. Abdullah-Al-Mamun, Sanjay Singh Rathore

et al.

Aquaculture Reports, Journal Year: 2023, Volume and Issue: 32, P. 101727 - 101727

Published: Sept. 13, 2023

Spirulina is a popular edible blue-green alga that has piqued the interest of aqua-feed formulations due to its high concentration micronutrients, macronutrients, and antioxidants. To investigate impacts natural as feed additive on Stinging catfish (Heteropneustes fossilis) growth, utilization, hematology serum biochemistry, gut morphology, well disease resistance Aeromonas hydrophila, 60-day feeding experiment was performed. The fish (N = 240), with an initial weight 4.23 ± 0.50 g, were placed in 12 aquaria tanks (100 L/ tank) fed twice daily until they satisfied. Four different experimental diets: 0% (D0, control diet), 1% (D1), 3% (D2), 5% (D3) meal used fish. This study found diet obtained notably higher (p < 0.05) specific growth rate, final weight, gain, average gain than other supplemented regimens. Furthermore, inclusion diets increased, utilization parameters such conversion ratio protein efficiency improved remarkably 0.05). Red blood cell, white lymphocytes, neutrophil, monocytes, basophil, hemoglobin, red cell distribution width-standard deviation, mean corpuscular hemoglobin all substantially greater diet-fed basal had lower total protein, globulin, albumin levels glucose, cholesterol, triglyceride those test diets. Compared groups, light microscopic examination intestinal tissues revealed well-organized enterocytes, intact epithelial barrier, abundant goblet cells, lacking luminal debris, exhibited no signs inflammation (edema). significantly affected villi height width, mucosa crypt depth, villi, lumen area. demonstrated (68.57%) A. hydrophila during bacterial challenge trial. Based findings, applying powder at supplement could benefit H. fossilis nutrient performance, health status, resistance.

Language: Английский

Citations

23

Effect of cheese whey on phycobiliproteins production and FAME profile by Arthrospira platensis (Spirulina): Promoting the concept of a circular bio-economy DOI
Andrea Cavallini,

Serenella Torre,

Luca Usai

et al.

Sustainable Chemistry and Pharmacy, Journal Year: 2024, Volume and Issue: 40, P. 101625 - 101625

Published: May 30, 2024

Language: Английский

Citations

8

Microalgae as an innovative active ingredient for edible films and coatings for food applications DOI
Marianne Ayumi Shirai, Tahís Regina Baú, Juliano Zanela

et al.

Algal Research, Journal Year: 2025, Volume and Issue: unknown, P. 103959 - 103959

Published: Feb. 1, 2025

Language: Английский

Citations

1

Rapid Screening of Microalgae as Potential Sources of Natural Antioxidants DOI Creative Commons
Na Wang,

Haiwei Pei,

Wenzhou Xiang

et al.

Foods, Journal Year: 2023, Volume and Issue: 12(14), P. 2652 - 2652

Published: July 10, 2023

In order to rapidly screen microalgae species as feedstocks for antioxidants, extracts were obtained from 16 strains (under 11 genera, 7 classes) using two methods: a one-step extraction with ethanol/water and three-step fractionating procedure hexane, ethylacetate, water successively. Measuring the total phenol content (TPC), carotenoid (TCC), antioxidant activity of extracts, indicating TPC TCC, played an important role in determining microalgae. A weighted scoring system was used evaluate activity, scores microalgal samples methods calculated same system. Among investigated microalgae, Euglena gracilis SCSIO-46781 had highest score, contributing high followed by Arthrospira platensis SCSIO-44012, Nannochloropsis sp. SCSIO-45224, Phaeodactylum tricornutum SCSIO-45120, SCSIO-45006, respectively. Additionally, above-mentioned five are currently being applied commercial production, this could be effective not only screening but also species/strains strong adaptation environmental stress, which is critical trait their cultivation.

Language: Английский

Citations

17

A Dendritic Cell-Recruiting, Antimicrobial Blood Clot Hydrogel for Melanoma Recurrence Prevention and Infected Wound Management DOI

Wen-Shang Liu,

Zhengmao Lu, Xiaohui Pu

et al.

Biomaterials, Journal Year: 2024, Volume and Issue: 313, P. 122776 - 122776

Published: Aug. 30, 2024

Language: Английский

Citations

6

Evaluation of Cladophora and Chlamydomonas microalgae for environmental sustainability: A comparative study of antimicrobial and photocatalytic dye degradation DOI

Samriti Guleria,

Halis Şimşek, Prince Chawla

et al.

Environmental Pollution, Journal Year: 2023, Volume and Issue: 340, P. 122806 - 122806

Published: Nov. 3, 2023

Language: Английский

Citations

10