Revealing culturable fungal microbiome communities from the Arabian Peninsula desert representing a unique source of biochemicals for drug discovery and biotechnology DOI Creative Commons
Walaa K. Mousa,

Najwa Alramadan,

Rose Ghemrawi

et al.

F1000Research, Journal Year: 2024, Volume and Issue: 13, P. 1527 - 1527

Published: Dec. 17, 2024

Background Microbes living at extremes evolve unique survival strategies to adapt challenging environmental conditions. Among these is their distinctive metabolic potential and ability produce specialized metabolites enabling them compete for limited resources defend against predators. These have significant in pharmaceutical industrial applications, particularly the development of drugs biochemicals. Objectives This study aimed investigate culturable fungal communities associated with four desert plants surrounding soils Arabian Peninsula identify bioactive properties. Methods A total 12 distinct species were isolated from soils. Each plant hosted a set fungi, demonstrating diversity desert-adapted communities. Biological activities extracts evaluated through various assays, including antimicrobial, antifungal, anticancer, antioxidant Results Panicum turgidum harbors most diverse community, dominated by genera such as Mucor, Aspergillus, Colletotrichum, Alternaria, Chaetomium. Aspergillus comprise 33% isolates, followed Fusarium 16%. All exhibit activities, highest phenolic flavonoid content. Fungi P. turgidum, Mucor sp., Curvularia display potent activity Staphylococcus aureus, while Chaetomium sp. moderate inhibition Pseudomonas aeruginosa. Conclusion highlights importance exploring extremophilic microorganisms, those found ecosystems, they offer wealth compounds that could address current challenges drug discovery biotechnology.

Language: Английский

Drought-induced microbial dynamics in cowpea rhizosphere: Exploring bacterial diversity and bioinoculant prospects DOI Creative Commons
Boshra Ahmed Halo,

Yaqeen A. S. Aljabri,

Mahmoud W. Yaish

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(3), P. e0320197 - e0320197

Published: March 25, 2025

Rhizospheric bacterial communities in plants contribute to drought resilience by promoting plant-soil interactions, yet their biodiversity and ecological impacts are not fully characterized. In cowpeas, these interactions may be crucial enhancing tolerance conditions. this study, cowpea were subjected treatment, the soil attached roots was collected, environmental DNA (e-DNA) extracted, identified as amplicon sequence variants (ASVs) metagenomics analysis of 16S rRNA gene. Microbial under control conditions analyzed using taxonomy diversity metrics. The sequencing results revealed 5,571 ASVs, taxonomic 1,752 species. Alpha beta analyses showed less conserved microbial community structures compositions among samples isolated from rhizosphere compared untreated samples, implying enhancement effect on species’ richness. differential accumulation 75 species that accumulated significantly ( P ≤ 0.05) response drought, including 13 exclusively present, seven absent, 46 forming a high-abundance cluster within hierarchical heatmap. These also grouped into specific clades phylogenetic tree, suggesting common genetic ancestry potentially shared traits associated with tolerance. differentially list included previously characterized saline habitats. findings suggest stress alters composition abundance epiphytic communities, impacting rhizosphere’s balance cowpeas. highlight adaptations enhance plant through improved mitigation, providing meaningful understandings for advancing sustainable agriculture developing microbial-based strategies boost crop productivity drought-prone regions.

Language: Английский

Citations

1
Enhancing soybean growth under drought stress through bio-priming with desert endophyte Priestua endophytica strain RAE-11 DOI

Mahima Choudhary,

Bhakti Patel,

Margi Patel

et al.

Symbiosis, Journal Year: 2025, Volume and Issue: unknown

Published: April 5, 2025

Language: Английский

Citations

0
The design and development of EcoBiomes: multi-species synthetic microbial consortia inspired by natural desert microbiome to enhance the resilience of climate-sensitive ecosystems DOI Creative Commons
Walaa K. Mousa, Rose Ghemrawi, Tareq Abu‐Izneid

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(16), P. e36548 - e36548

Published: Aug. 1, 2024

Synthetic microbial communities, which simplify the complexity of natural ecosystems while retaining their key features, are gaining momentum in engineering and biotechnology applications. One potential application is development bioinoculants, offering an eco-friendly, sustainable solution to promote plant growth increase resilience abiotic stresses amidst climate change. A source for stress-tolerant microbes those associated with desert plants, evolved shaped by selective pressures host health under harsh environmental conditions. In our research, we aim design develop synthetic consortia inspired microbiota four plants native Arabian Peninsula, inferred from previous work identifying structure predicting function these communities using high throughput eDNA barcoding. To obtain culturable that manageable traceable yet still representative combined multiple experimental protocols coupled compatibility synergy assessments, along planta testing. We isolated a total 75 bacteria conducted detailed biological evaluations, revealing overwhelming majority (84 %) all isolates produced indole acetic acid (IAA), 73 % capable solubilizing phosphate, 60 producing siderophores, 47 forming biofilms, 35 ACC deaminase, contributing stress tolerance. constructed consortia, named EcoBiomes, consisting synergistic combinations species can co-exist without significant antagonism. Our preliminary data indicate EcoBiomes enhance heterologous simulated stresses, including drought, heat, salinity. offer unique, sustainable, eco-friendly mitigate impact change on sensitive ecosystems, ultimately affecting global food security.

Language: Английский

Citations

1
Exploring agro-ecological significance, knowledge gaps, and research priorities in arbuscular mycorrhizal fungi DOI Creative Commons

Lenganji Lackson Mwampashi,

Aneth Japhet Magubika,

Job Frank Ringo

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 1, 2024

This systematic review examines the global agricultural relevance and practical environmental implications of arbuscular mycorrhizal fungi (AMF) within phylum Glomeromycota. Following PRISMA guidelines, ensuring a comprehensive unbiased literature review, search was conducted, focusing on functional roles AMF in enhancing crop productivity, nutrient uptake, soil health. Key findings reveal that contribute significantly to sustainable agriculture by reducing need for chemical fertilizers increasing plant resilience stressors like drought, salinity, or pest resistance. The highlights importance forming symbiotic relationships with plants, which enhance absorption improve structure, showcasing long-term benefits such as reduced erosion improved water retention. However, current lacks in-depth exploration taxonomy evolutionary aspects AMF, well specific they play different contexts, e.g., understanding evolution could strain selection crops. identifies several urgent research gaps, including more refined community dynamics under varying land management practices. For example, there are gaps critical evaluation advanced molecular techniques. Such techniques essential studying these interactions. Addressing will integration into systems ecosystem practices across geographical regions. Future should prioritize developing precise imaging optimizing applications crops types maximize their ecological benefits. be through interdisciplinary collaboration (e.g., involving biologists, agronomists, etc.). In conclusion, this advances application its contribution biodiversity conservation agroecosystems. Integrating policy frameworks encourage farming practices, promote adoption inoculants, foster incentives environmentally friendly strategies.

Language: Английский

Citations

1
Revealing culturable fungal microbiome communities from the Arabian Peninsula desert representing a unique source of biochemicals for drug discovery and biotechnology DOI Creative Commons
Walaa K. Mousa,

Najwa Alramadan,

Rose Ghemrawi

et al.

F1000Research, Journal Year: 2024, Volume and Issue: 13, P. 1527 - 1527

Published: Dec. 17, 2024

Background Microbes living at extremes evolve unique survival strategies to adapt challenging environmental conditions. Among these is their distinctive metabolic potential and ability produce specialized metabolites enabling them compete for limited resources defend against predators. These have significant in pharmaceutical industrial applications, particularly the development of drugs biochemicals. Objectives This study aimed investigate culturable fungal communities associated with four desert plants surrounding soils Arabian Peninsula identify bioactive properties. Methods A total 12 distinct species were isolated from soils. Each plant hosted a set fungi, demonstrating diversity desert-adapted communities. Biological activities extracts evaluated through various assays, including antimicrobial, antifungal, anticancer, antioxidant Results Panicum turgidum harbors most diverse community, dominated by genera such as Mucor, Aspergillus, Colletotrichum, Alternaria, Chaetomium. Aspergillus comprise 33% isolates, followed Fusarium 16%. All exhibit activities, highest phenolic flavonoid content. Fungi P. turgidum, Mucor sp., Curvularia display potent activity Staphylococcus aureus, while Chaetomium sp. moderate inhibition Pseudomonas aeruginosa. Conclusion highlights importance exploring extremophilic microorganisms, those found ecosystems, they offer wealth compounds that could address current challenges drug discovery biotechnology.

Language: Английский

Citations

0