Maternal and Neonatal Outcomes Associated with Mild COVID-19 Infection in an Obstetric Cohort in Brazil

American Journal of Tropical Medicine and Hygiene, Journal Year: 2022, Volume and Issue: 107(5), P. 1060 - 1065

Published: Oct. 17, 2022

Previous coronavirus epidemics were associated with increased maternal morbidity, mortality, and adverse obstetric outcomes. Reports for SARS-CoV-2 indicate that the population is at risk severe illness, although there are still limited data on mild COVID-19 infection during pregnancy. To determine association between pregnancy, neonatal outcomes, we performed a prospective cohort study among pregnant women control group. Postnatal depressive symptoms assessed using Edinburgh Depression Scale. We recruited 84 88 without COVID-19. All participants unvaccinated. The most common acute headache (82.1%), loss of smell (81%), asthenia (77.4%). median duration long COVID was 60 days (interquartile range, 130). Pregnant diagnosis greater ultrasound abnormalities-mainly, fetal growth restriction (relative [RR], 12.40; 95% CI, 1.66-92.5), premature birth (RR, 2.62; 1.07-6.43), postpartum depression 2.28; 1.24-4.21). Our results alert clinicians to consequences even in cases, given abnormalities, birth, symptoms, depression. National guidelines preventive measures treatments should be based scientific evidence, including attention impact health family needs after pandemic.

Language: Английский

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Effects of fast-acting antidepressant drugs on a postpartum depression mice model

Biomedicine & Pharmacotherapy, Journal Year: 2022, Volume and Issue: 154, P. 113598 - 113598

Published: Aug. 25, 2022

Postpartum depression (PPD) is a severe psychiatric disorder with devastating consequences on child development and mother's health. Dysregulation of glutamatergic GABAergic signalling has been described in the corticolimbic system PPD patients, who also show downregulation allopregnanolone levels serum. Consequently, synthetic allopregnanolone-based treatment current eligible drug to treat patients. Alternatively, ketamine appears be promising medication for preventing PPD, nevertheless differences efficacy between both treatments remains unknown due lack comparative studies. On this basis, present study aims compare effectiveness PPD-like mouse model. Our results that postpartum females undergoing maternal separation early weaning (MSEW) protocol increased despair-like behaviour, anhedonia disrupted care. Such symptoms are accompanied by lower serum levels, reduction vesicular transporters GABA (VGAT) glutamate (VGLUT1) infralimbic cortex (IL), as well decreased hippocampal cellular proliferation. Furthermore, drugs prevent behaviour while only reverts anhedonia. Both increase neurogenesis, raises VGAT VGLUT1 markers IL. These findings suggest might even more effective than allopregnanolone, which points out necessity including clinical studies Altogether, we propose new mice model recapitulates core symptomatology molecular alterations shown allows us further investigate neurobiology therapeutic potential antidepressant drugs.

Language: Английский

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“Showing Everybody’s True Colors”: Informal networks of low-income single mothers and their young children during the COVID-19 pandemic

Children and Youth Services Review, Journal Year: 2022, Volume and Issue: 137, P. 106479 - 106479

Published: March 16, 2022

Language: Английский

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Associations between breastfeeding intention, breastfeeding practices and post‐natal depression during the COVID‐19 pandemic: A multi‐country cross‐sectional study

Maternal and Child Nutrition, Journal Year: 2022, Volume and Issue: 19(1)

Published: Nov. 9, 2022

Abstract Associations between breastfeeding intention, duration and post‐natal depression (PND) have been shown in pre‐COVID‐19 studies. However, studies during COVID‐19 not examined the associations practices, PND an international sample of women, taking into consideration related factors. This is first study to address this gap as both may be affected by COVID‐19, important long‐term effects on women's infant's health. A cross‐sectional internet‐based survey was conducted with 3253 women from five countries: Brazil, South Korea, Taiwan, Thailand, United Kingdom July November 2021. The results showed that who intended breastfeed pregnancy had lower odds having than did intend to. Women no intention but actually breastfed greater (AOR 1.75) breastfed. While there statistical significance expressed breast milk feeding multivariable logistic regression models, shorter directly they planned 1.58) those longer even after adjusting for covariates including COVID‐19‐related variables. These findings suggested importance working their intention. Tailored support required ensure needs are met at same time care maternal mental health beyond pandemic.

Language: Английский

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Mental Health in Obstetric Patients and Providers During the COVID-19 Pandemic

Clinical Obstetrics & Gynecology, Journal Year: 2021, Volume and Issue: 65(1), P. 203 - 215

Published: Dec. 1, 2021

Psychiatric morbidity is the most common childbirth complication with 1 in 5 women experiencing a perinatal mood or anxiety disorder. The cost of this psychiatric pervasive, contributing to devastating maternal health, child developmental, and economic consequences. coronavirus disease 2019 (COVID-19) pandemic, associated changes experiences, resulted profound psychological reactions including increased anxiety, depression, stress disorders, sleep disturbance, further impacting obstetric patients. Providers' mental health has been challenged by moral injury shared trauma. This article reviews outcomes regard COVID-19 pandemic for patients their providers.

Language: Английский

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Postnatal depression and anxiety during the COVID-19 pandemic: The needs and experiences of New Zealand mothers and health care providers

Midwifery, Journal Year: 2022, Volume and Issue: 115, P. 103491 - 103491

Published: Sept. 21, 2022

Language: Английский

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Evolutionary Perspectives on Depression

Cambridge University Press eBooks, Journal Year: 2022, Volume and Issue: unknown, P. 117 - 133

Published: Sept. 29, 2022

We propose that major depressive disorder is not a unitary disease. Instead, different triggering factors causing periods of low mood can give rise to and sometimes even opposite symptom patterns. Some the symptoms depression are maladaptive; others may be psychobehavioural adaptions solve adaptive problem triggered episode. It therefore logical subtype episodes according their factors. In evolutionary psychiatry, classified into discrete subtypes induced by infection, long-term stress, loneliness, traumatic experience, hierarchy conflict, grief, romantic relationship dissolution, post-partum events, season, chemicals, somatic diseases starvation. hunter-gatherers in people who have traditional lifestyles, only rarely turn fulfil diagnostic criteria disorder. Modern lifestyles cause low-grade inflammation an increased susceptibility chronic which introduce sickness behaviour reactive short-term changes. Therefore, features contemporary environments prevent normalisation after adverse life resulting An approach helps identify our contribute greater this debilitating disorder, inform both prevention treatment depression. further should tailored patient's subtype, focusing on root causes rather than alleviating with drugs.

Language: Английский

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The impact of COVID-19 lockdown on postpartum mothers in London, England: An online focus group study

Journal of Public Health, Journal Year: 2023, Volume and Issue: 32(8), P. 1577 - 1589

Published: May 15, 2023

This study examines the impact of COVID-19 lockdown on postpartum mothers in England, with aim identifying opportunities to improve maternal experience and wellbeing. The postpartum/postnatal period is widely acknowledged as a time when require greater levels support from multiple sources. However, stay-at-home orders, commonly known "lockdown," deployed some countries limit transmission reduced access support. In many navigated household isolation within an intensive mothering expert parenting culture. Examining may reveal strengths weaknesses current policy practice.We conducted online focus groups involving 20 living London, "lockdown babies," following up our earlier survey social We thematically analysed group transcripts, identified key themes around Lockdown Experience Determinants Experience.Participants raised positives lockdown, including fostering connections protection external expectations, but also negatives, isolation, institutional abandonment, intense relationships household. Potential reasons behind variations include physical environments, timing birth, number children. Our findings reflect how systems be "trapping" families into male-breadwinner/female-caregiver family model, while culture increasing stress undermining responsive mothering.Facilitating partners stay at home during (e.g., paternity leave flexible working) establishing peer/community decentre reliance professional experts promote positive wellbeing.The version contains supplementary material available 10.1007/s10389-023-01922-4.

Language: Английский

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First-generation Nigerian mothers living in the UK and their experience of postnatal depression: an interpretative phenomenological analysis

Ethnicity and Health, Journal Year: 2022, Volume and Issue: 28(5), P. 738 - 756

Published: Oct. 1, 2022

Previous studies emphasise the negative psychological and physical consequences of Postnatal Depression (PND) on mothers children's health. In UK, around 10-20% women can be affected by perinatal mental health problems. Minority ethnic groups such as Black African are considered to at greater risk developing PND data estimates that immigrant twice more likely develop than native mothers. The unique experiences needs this culturally diverse group remain little explored in UK. To address gap literature, study aimed explore lived First-Generation Nigerian Mothers (FGNMs) who suffered PND, their coping behaviours treatment UK.Six FGNMs with a previous diagnosis were purposefully recruited from GP practices social attended Semi-structured interviews analysed using Interpretative Phenomenological Analysis.Three master seven subordinate themes identified: (i) Socio-cultural factors (Inter-generational transmission; cultural perceptions: shame stigma; transitions: adjusting new culture); (ii) What about me? neglected nurturer (experiences treatment; pretending OK); (iii) Loneliness (lack support partner; self-reliance).The provides evidence difficulties encountered relation including socio-cultural factors, neglect family healthcare professionals, self-reliance strategy. Contrary reports suggesting do not seek help for needs, participants' accounts indicated attempts engage professionals met unsatisfactory responses. findings highlight need barriers affecting access services fostering patient-centred sensitive approach teams effectively an early stage detection pathway.

Language: Английский

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Breastfeeding Practices and Postpartum Depression in Mexican Women during the COVID-19 Pandemic: A Cross-Sectional Study

Medicina, Journal Year: 2023, Volume and Issue: 59(7), P. 1330 - 1330

Published: July 19, 2023

Background: Breastfeeding is a characteristic process of mammals that ensures delivery an adequate nutritional supply to infants. It the gold standard food source during infant’s first months life. Since onset COVID-19 pandemic in 2020, people quarantine have experienced wide range feelings, which may make isolation challenging terms maternal health. This study focused on prevalence breastfeeding practices and postpartum depression (PPD) among Mexican women pandemic. Materials Methods: cross-sectional included 586 who completed online survey 4−8 weeks after from April December 2020 Guadalajara, Mexico. The aim was identify potentially depressed mothers according Edinburgh Postnatal Depression Scale (EPDS) describe their practices. Results: mean age 30.4 ± 4.6 years, EPDS score 9.6 5.0, PPD scores 27.1%. Exclusive (EBF) reported by 32.3% 48 h 70.3% delivery. EBF associated with lower (p = 0.015) 0.001) Skin-to-skin contact (SSC) 385 (65.7%) mothers. less frequent practicing SSC (20.3%) than it those not (40.3%) 0.001). A higher percentage practiced breastfed (66.9%) used (150, 79.4%) 0.012 0.001, respectively). Conclusions: Results suggest emergency restrictions imposed population significantly affected well-being birth, these effects posed risks mental health emotional stability Therefore, encouraging BF or improve limit depressive symptoms

Language: Английский

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