Journal of Comprehensive Pediatrics,
Journal Year:
2024,
Volume and Issue:
15(3)
Published: April 29, 2024
:
Since
the
start
of
Coronavirus
disease
(COVID-19)
pandemic,
people
have
had
to
cope
with
significant
mental
pressure
regarding
this
mysterious
infection.
The
rapid
spread
syndrome
coronavirus
2
(SARS-CoV-2)
worldwide
has
led
immense
anxiety
and
depression
among
people,
especially
in
immunocompromised
population
their
close
relatives.
This
study
aims
evaluate
health
patients
primary
immune
deficiency
(PID)
mothers
during
first
year
COVID-19
outbreak.
A
cross-sectional
was
conducted
from
September
2020
March
2021
pediatric
PID
family
members.
Thirty
were
investigated
using
Zung
Self-Rating
Anxiety
Scale
Beck
Inventory
(BAI),
respectively.
results
showed
that
younger
experienced
higher
levels
(P-value
=
0.019).
Additionally,
who
did
not
comply
quarantine
measures
significantly
0.02).
indicate
mild
moderate
aged
12.1
±
1.46
years
Furthermore,
there
observed
patients.
Non-compliance
contributed
scores
both
groups,
emphasizing
importance
staying
home
adhering
restricted
social
interactions
improve
health.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(7), P. e28325 - e28325
Published: March 18, 2024
BackgroundPeriodontal
disease
and
coronary
heart
are
both
prevalent
diseases
worldwide
cause
patients
physical
mental
suffering
a
global
burden.
Recent
studies
have
suggested
link
between
periodontal
disease,
but
there
is
less
research
in
this
field
from
the
perspective
of
bibliometrics.ObjectiveThis
study
aimed
to
quantitatively
analyze
literature
on
summarize
intellectual
bases,
hotspots,
emerging
trends
pave
way
for
future
research.MethodsThe
Science
Citation
Index
Expanded
database
was
used
retrieve
records
1993
2022.
After
manual
screening,
data
were
cooperative
network
analysis
(including
countries/regions,
institutions
authors),
keyword
analysis,
reference
co-citation
by
CiteSpace
software.
Microsoft
Excel
2019
applied
curve
fitting
annual
trend
publications
citations.ResultsA
total
580
included
analysis.
The
number
citations
has
shown
an
upward
over
past
30
years.
There
direct
collaboration
among
authors
closer
countries.
United
States
country
with
most
published
articles
(169/580,
29.14%).
Based
results
C-reactive
protein,
oral
flora,
atherosclerosis,
infection,
inflammation
previous
while
burden
cardiovascular
outcomes
considered
field.ConclusionStudies
which
attracted
attention
increasing
researchers,
been
successfully
analyzed
using
bibliometrics
visualization
techniques.
This
paper
will
help
scholars
better
understand
dynamic
evolution
point
out
direction
research.Clinical
significanceThis
presents
overview
disease.
Further
exploration
two
themselves
potential
causal
relationship
necessary
relevant,
may
impact
basic
research,
diagnosis,
treatment
related
diseases.
aid
work
researchers
specialist
doctors,
ultimately
benefit
PLOS mental health.,
Journal Year:
2024,
Volume and Issue:
1(3), P. e0000015 - e0000015
Published: Aug. 5, 2024
We
investigate
how
select
identity
characteristics
moderate
the
role
of
several
SDoH
domains
on
major
depressive
disorder
(MDD).
Our
study
considers
an
analytical
sample
86,954
participants
from
NIH-funded
All
Us
(AoU)
Research
Program
in
USA.
independent
variables
and
moderators
come
survey
responses
our
outcome
is
EHR
diagnostic
code.
include
race/ethnicity
gender/sexual
to
food
insecurity,
discrimination,
neighborhood
social
cohesion,
loneliness
assessing
risk
for
MDD
diagnosis.
examine
those
moderating
effects
based
connections
seen
literature.
findings
illustrate
complexity
where
people
live
their
lives
can
have
significant
differential
impact
MDD.
Women
(AOR
=
1.60,
95%
CI
[1.53,
1.68])
LGBTQIA2+
individuals
1.71,
[1.60,
1.84])
exhibit
a
significantly
higher
likelihood
diagnosis
compared
cisgender
heterosexual
males.
also
reveals
lower
among
Asian/Asian
American
0.41,
[0.35,
0.49])
White
individuals.
results
align
with
previous
research
indicating
that
levels
insecurity
1.30,
[1.17,
1.44])
6.89,
[6.04,
7.87])
are
strongly
associated
increased
However,
we
find
cohesion
0.92,
[0.81,
1.05])
does
not
emerge
as
predictor,
contradicting
some
literature
emphasizing
protective
cohesion.
Similarly,
finding
transience
0.95,
[0.92,
0.98])
reduces
contradicts
conventional
wisdom
warrants
further
exploration.
provides
reminder
substantial
challenges
focused
marginalized
community
segments
deliberate
sampling
plans
needed
most
underserved.
BMC Psychiatry,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: March 11, 2025
Mental
disorders
are
a
major
public
health
issue,
causing
4.9%
of
global
disability-adjusted
life
years
(DALYs).
In
Jordan,
factors
like
regional
conflicts,
economic
changes,
and
population
growth
contribute
to
this
burden.
This
study
examines
the
trends
risk
mental
in
Jordan
from
1990
2021
using
Global
Burden
Disease
(GBD)
data.
We
analyzed
prevalence,
deaths,
DALYs
GBD
dataset,
reporting
both
all-age
numbers
age-standardized
rates.
Key
factors,
including
behavioral
risks,
bullying,
childhood
sexual
abuse,
substance
use,
were
assessed.
disorder
cases
rose
by
279.8%,
514,234
1,953,087
2021.
Anxiety
depression
most
common
All-age
increased
649.6%,
while
DALY
rates
showed
slight
4.3%
rise.
Females
had
higher
prevalence
rates,
males
use
Behavioral
abuse
contributors.
The
burden
has
grown
significantly
over
three
decades.
Limited
resources,
stigma,
instability
worsen
issue.
Policies
focusing
on
stigma
reduction,
integration,
prevention
essential.
Signal Transduction and Targeted Therapy,
Journal Year:
2023,
Volume and Issue:
8(1)
Published: Dec. 6, 2023
The
coronavirus
disease
2019
(COVID-19)
pandemic
has
been
looming
globally
for
three
years,
yet
the
diagnostic
and
treatment
methods
COVID-19
are
still
undergoing
extensive
exploration,
which
holds
paramount
importance
in
mitigating
future
epidemics.
Host
non-coding
RNAs
(ncRNAs)
display
aberrations
context
of
COVID-19.
Specifically,
microRNAs
(miRNAs),
long
(lncRNAs),
circular
(circRNAs)
exhibit
a
close
association
with
viral
infection
progression.
In
this
comprehensive
review,
an
overview
was
presented
expression
profiles
host
ncRNAs
following
SARS-CoV-2
invasion
potential
functions
development,
encompassing
invasion,
replication,
immune
response,
multiorgan
deficits
include
respiratory
system,
cardiac
central
nervous
peripheral
system
as
well
COVID.
Furthermore,
we
provide
several
promising
ncRNA
biomarkers
diverse
clinical
scenarios
related
to
COVID-19,
such
stratification
biomarkers,
prognostic
predictive
response.
addition,
also
discuss
therapeutic
presenting
ncRNA-based
strategies
facilitate
development
novel
treatments.
Through
in-depth
analysis
interplay
between
combined
our
bioinformatic
analysis,
hope
offer
valuable
insights
into
stratification,
prognosis,
South African Journal of Psychology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 4, 2025
The
impact
of
the
pandemic
has
diminished,
and
while
it
is
still
present,
no
longer
causes
same
degree
societal
disruption
as
before.
nature
this
also
shifted.
Considering
psychosocial
economic
triggered
by
COVID-19,
study
explores
adverse
financial
consequences
COVID-19
restrictions
its
mental
health
on
household
heads.
employed
a
quantitative
cross-sectional
survey
research
design.
A
questionnaire
was
distributed
to
nationally
representative
sample
individuals
(
N
=
1580)
through
computer-assisted
telephone
interviewing
self-completion.
From
dataset,
550
heads
who
were
before
implementation
regulations
selected
for
inclusion
in
study.
Findings
reveal
that
there
discernible
gender
differences
terms
distress
experienced
during
females
more
prone
psychological
compared
males
period.
These
results
offer
insights
into
disparities
concerning
repercussions
COVID-19.
Policy
initiatives
interventions
should
consciously
address
specific
needs
females,
aiming
not
only
mitigate
current
pandemic’s
but
fortify
resilience
against
potential
future
crises.
BMC Nephrology,
Journal Year:
2024,
Volume and Issue:
25(1)
Published: Jan. 15, 2024
Abstract
Background
Previous
Mendelian
studies
identified
a
causal
relationship
between
renal
function,
as
assessed
by
estimated
glomerular
filtration
rate
(eGFR),
and
severe
infection
with
coronavirus
disease
2019
(COVID-19).
However,
much
is
still
unknown
because
of
the
limited
number
associated
single
nucleotide
polymorphisms
(SNPs)
COVID-19
lack
cystatin
C
testing.
Therefore,
in
present
study,
we
aimed
to
determine
genetic
mechanisms
responsible
for
association
eGFR
European
population.
Methods
We
performed
bidirectional
randomization
(MR)
analysis
on
large-scale
genome-wide
study
(GWAS)
data;
log-eGFR
was
calculated
from
serum
levels
creatinine
or
applying
Chronic
Kidney
Disease
Genetics
(CKDGen)
Meta-analysis
Dataset
combined
UK
Biobank
(N
=
1,004,040)
phenotypes
(122,616
cases
2,475,240
controls)
COVID19-hg
GWAS
meta-analyses
round
7.
The
inverse-variance
weighted
method
used
main
estimation.
Results
Analyses
showed
that
genetically
instrumented
reduced
log-eGFR,
creatinine,
significantly
higher
risk
(odds
ratio
[OR]:
2.73,
95%
confidence
interval
[CI]:
1.38–5.41,
P
<
0.05)
related
hospitalization
(OR:
2.36,
CI:
1.39–4.00,
1.24,
1.01–1.53,
0.05).
significance
these
associations
remained
when
using
based
instrumented.
COVID-19,
regardless
phenotype,
not
either
C.
Conclusions
Our
findings
suggest
genetical
predisposition
kidney
function
may
represent
factor
COVID-19.
consistent
significant
effect
this
study.
Healthcare,
Journal Year:
2022,
Volume and Issue:
10(10), P. 2025 - 2025
Published: Oct. 14, 2022
Clinical
experience
and
scientific
studies
highlight
the
pivotal
role
that
primary
health
care
services
have
should
as
a
gateway
to
system
first
point
of
contact
for
patients
with
mental
disorders,
particularly—but
not
exclusively—for
disorder
in
spectrum
common
disorders
[...]