European Neuropsychopharmacology, Journal Year: 2024, Volume and Issue: 92, P. 52 - 61
Published: Dec. 24, 2024
Language: Английский
Schizophrenia Bulletin Open, Journal Year: 2024, Volume and Issue: 5(1)
Published: Jan. 1, 2024
Abstract The Cognitive Assessment Interview (CAI) is an interview-based scale measuring cognitive impairment and its impact on functioning in subjects with schizophrenia (SCZ). It approved as a coprimary measure of performance-based instruments, such the Measurement Treatment Research to Improve Cognition Schizophrenia Consensus Battery (MCCB). Recent research highlights negative symptoms, social cognition, functional capacity mediators impairment’s functioning. This study compared mediation analysis outcomes using CAI or MCCB scores, providing insights into utility tools clinical practice. included 618 individuals diagnosed schizophrenia, recruited from 24 Italian psychiatric clinics. Neurocognitive assessments utilized both MCCB. Mediation analyses explored neurocognition real-life domains. study’s results extend validation that provides valid information possible mediators, complementing obtained Interview-based assessment might be essential for understanding complexity various domains clinicians, patients, caregivers.
Language: Английский
Citations
4
International Journal of Forensic Mental Health, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 4, 2025
Individuals in forensic mental health services (FMHS) commonly exhibit greater cognitive deficits and unmet needs than those general psychiatric care. Despite the central role of functional disability FMHS treatment objectives, assessment this domain remains underexplored. This study examines current practices Swedish through combination a survey analysis register data. The covered presence content procedure manuals regarding clinical use results. Frequency relation to individual factors (age, gender, place birth, diagnosis, history addiction) contextual (FMHS site, size security level at administrated risk assessment) were investigated statistical Results indicate significant variability across different sites. Contextual such as site instruments demonstrate positive association with frequency. Functional assessments primarily used in-patients, raising concerns about applicability beyond hospital settings preparation for community re-entry. professionals’ belief potential benefits tailoring interventions, its impact on plans was limited. underscores need improved accuracy ongoing monitoring functioning, particularly considering disparate observed Moreover, there is call national coordination evidence-based guidelines enhance FMHS.
Language: Английский
Citations
0
IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 12, 2025
Psychotic Spectrum Disorders (PSDs) affect approximately 1 in 300 people worldwide and encompass a range of positive symptoms, such as hallucinations, delusions, disorganized thinking, well negative including alogia, avolition, diminished emotional expression. In addition, with PSDs frequently present impairments cognitive domains, executive function, memory, attention, social cognition, which lead to difficulties independent living, employment, interpersonal relationships. This chapter explores the neuropsychological dimension psychosis provides thorough summary deficits linked PSDs. The neurobiological underpinnings these are discussed, examining PSD differentiations brain structure function. Instruments used for evaluation presented, supporting crucial role formal plays diagnosis treatment. Modern therapeutic modalities, remediation therapies, pharmaceutical interventions, technologies like neurostimulation digital therapeutics, discussed. closes by discussing implications future study clinical application, highlighting necessity integrated, culturally relevant, ethical approaches rehabilitation symptom management. Through this work, authors aim support better understanding promote more efficient, comprehensive care
Language: Английский
Citations
0
Schizophrenia Bulletin, Journal Year: 2025, Volume and Issue: unknown
Published: March 6, 2025
Cognitive impairments in patients with schizophrenia initiate a cascade of effects on daily functioning. A single impairment can affect the functioning entire cognitive system. However, relative interdependence among individual neuropsychological measures-whether performance specific test depends other tests-remains poorly understood. The study included total 1027 participants (522 and 505 healthy controls) from China. All completed comprehensive 9-test Measurement Treatment Research to Improve Cognition Schizophrenia Consensus Battery. To examine relationships, we employed Gaussian Graphical Models for undirected relationships Bayesian networks directed tests. Symbol Coding played central role exhibited downstream associations tests both controls. Network analysis showed significant between-group edge differences networks, particularly between Continuous Performance Spatial Span (SS), Managing Emotions (P = .018). consistent sequential pattern (Symbol → SS Maze Trail Making) was identified networks. Notably, connection uniquely present patient's network. Importantly, were as variables schizophrenia, showing extensive connectivity is fundamental association appears be stable feature schizophrenia. These findings may inform mechanistic insights into architecture.
Language: Английский
Citations
0
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2025, Volume and Issue: 139, P. 111392 - 111392
Published: May 2, 2025
Language: Английский
Citations
0
psychopraxis neuropraxis, Journal Year: 2024, Volume and Issue: 27(2), P. 74 - 80
Published: Feb. 20, 2024
Zusammenfassung Die Schizophrenie ist eine schwere psychiatrische Störung, die mit Positiv- und Negativsymptomen sowie kognitiven Beeinträchtigungen einhergeht. Durch Fortschritte in der Pharmakologie seit den 1950er-Jahren es möglich geworden, Erkrankung deutlich positiv zu beeinflussen: Antipsychotika können Positivsymptome Agitation akuten Psychose verbessern. In letzten Jahren hat das Thema Beeinträchtigung im Zusammenhang (Cognitive impairment associated with schizophrenia [CIAS]) zunehmend an Bedeutung gewonnen. Dieser Artikel soll einen Überblick über neuesten Entwicklungen Diagnostik Therapie geben. Dazu gehören Beschreibung umfassender kognitiver Testbatterien kurzer Screeninginstrumente, für klinischen Alltag relevant sind, Vorstellung von Maßnahmen zur Remediation neuen pharmakologischen Ansätzen.
Citations
1
Annals of General Psychiatry, Journal Year: 2024, Volume and Issue: 23(1)
Published: Dec. 28, 2024
This randomized-controlled study evaluates the effectiveness of a newly developed social cognition rehabilitation intervention, modified Social Cognition Individualized Activity Lab (mSoCIAL), in improving and clinical functional outcomes persons with schizophrenia recruited two Italian sites: University Campania "Luigi Vanvitelli" Naples ASST Fatebenefratelli-Sacco Milan. mSoCIAL consists cognitive training module focusing on different domains narrative enhancement module. We assessed changes cognition, characteristics variables patients who participated 10 weekly sessions or received treatment as usual (TAU). A paired-sample t test repeated-measures MANOVA were used to investigate respectively within between-group differences. Twenty people blindly assigned 20 TAU. After weeks, significantly improved disorganization, emotion recognition, capacity real-life functioning. As compared TAU, group showed significant improvement minimal enriched inference domain theory mind, key functioning (interpersonal relationships, everyday life skills, work skills). schizophrenia. These results highlight importance deficit necessity for these interventions be multifaced personalized. Such an approach ensures that improvements translate into enhanced outcomes. Trial registration NCT05130853, registered 24 November 2021.
Language: Английский
Citations
1
Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(16), P. 4843 - 4843
Published: Aug. 16, 2024
Background: Cognitive impairment is a relevant problem in psychiatry and can be well assessed with cross-diagnostic test such as the Screen for Impairment Psychiatry (SCIP). The aim of our pilot study to assess cognitive acute psychiatric inpatients diagnosed psychotic disorders, bipolar disorder depression using German version SCIP (SCIP-G). We also investigate whether dysfunction improves over course inpatient treatment, where patients are offered combination pharmacological treatment remediation. Methods: A total 143 adult were included study. testing was performed two different forms SCIP-G. All received state-of-the-art pharmacotherapy remediation COGPACK® software package 6.06. Results: Based on ICD-10 Criteria Research, 54 given an F2 diagnosis (schizophrenia schizotypal delusional disorders). Thirty-nine met criteria (F30 F31) fifty (F32 F33). At baseline, significant difference observed between scores F32/33 (p < 0.001) F30/31 groups = 0.022). second measurement time point, score showed improvement all three 0.001), there no statistically interaction diagnostic 0.860). Conclusions: present disorders easily during hospital stay. In sample, more cognitively impaired at baseline than affective disorder. Inpatient consisting remediation, improved deficits. Patients similar improvements performance.
Language: Английский
Citations
0
Frontiers in Psychiatry, Journal Year: 2024, Volume and Issue: 15
Published: Oct. 2, 2024
Due to the high heterogeneity of schizophrenia, factors influencing social cognitive impairment are controversial. The purpose this study was investigate dysfunction deficit schizophrenia (DS), and explore its clinical impact on characteristics neurocognitive function assessment results.
Language: Английский
Citations
0
European Neuropsychopharmacology, Journal Year: 2024, Volume and Issue: 92, P. 52 - 61
Published: Dec. 24, 2024
Language: Английский
Citations
0