Current Phenomenon of Self-Harm in Children and Adolescents

Journal of korean Academy of Child and Adolescent Psychiatry, Journal Year: 2025, Volume and Issue: 36(2), P. 47 - 53

Published: April 1, 2025

Self-harm is a prevalent phenomenon among children and adolescents, its incidence has increased over time. This behavior often maladaptive coping mechanism caused by difficulties with emotional regulation. in adolescents predictor of future suicide attempts requires comprehensive management. study reviewed current holistic management self-harm adolescents. By synthesizing evidence-based practices, this shows that should include the recognition risk factors for suicidal behavior, early detection, pharmacological non-pharmacological therapies, prevention programs at all levels. aimed to increase awareness encourage participation from societal levels, including schools policymakers, handling

Language: Английский

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The Association Between Internet Addiction and Non‐Suicidal Self‐Injury Among Adolescents: A Meta‐Analysis

Journal of Adolescence, Journal Year: 2025, Volume and Issue: unknown

Published: April 28, 2025

Language: Английский

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Mechanisms of microbial-gut-brain axis modulation by electroconvulsive therapy in the treatment of depression

Anesthesiology and Perioperative Science, Journal Year: 2025, Volume and Issue: 3(2)

Published: May 7, 2025

Abstract Purpose The present study aims to evaluate the effects of electroconvulsive therapy (ECT) on depressive behaviors. In addition, we explore mechanisms by which ECT alters composition and functioning gut microbiota through microbiota-gut-brain axis. Methods A depression model in mice was established using chronic unpredictable mild stress. were divided into three groups: control, depression, ECT-treated. Depressive behaviors assessed a series behavioral tests, including monitoring body weight, open field sucrose preference forced swim tests. Histological microcirculatory assessments brain tissues conducted hematoxylin eosin (H&E) staining, Nissl staining immunofluorescence methodology along with laser speckle contrast imaging. inflammatory cytokines Tumor Necrosis Factor- α (TNF- ), Interleukin-6 (IL-6) Interleukin-1 β (IL-1 ) quantified enzyme-linked immunosorbent assay. Metagenomic sequencing employed diversity abundance microbiota. Results significantly improved as evidenced increased weight decreased immobility time H&E indicated substantial reduction inflammation while revealed restoration neuronal morphology following treatment. Furthermore, analysis showed elevated c-Fos expression hippocampal region ( P < 0.05). Assessments demonstrated significant reductions TNF- , IL-6, IL-1 levels group. metagenomic that enhanced diversity, particularly restoring Bacteroides Verrucomicrobia Conclusion exerts its antidepressant modulating enhancing functionality gut-brain

Language: Английский

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Metabolic Perturbations Associated with both PFAS Exposure and Perinatal/Antenatal Depression in Pregnant Individuals: A Meet-in-the-Middle Scoping Review

Current Environmental Health Reports, Journal Year: 2024, Volume and Issue: 11(3), P. 404 - 415

Published: June 19, 2024

Depression during the perinatal or antenatal period affects at least 1 in 10 women worldwide, with long term health implications for mother and child. Concurrently, there is increasing evidence associating maternal exposure to per- poly-fluoroalkyl substances (PFAS) adverse pregnancy outcomes. We reviewed body of examining both associations between PFAS perturbations metabolome, metabolome perinatal/antenatal depression. Through this, we sought explore existing as a potential mediation pathway linking

Language: Английский

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