Current Phenomenon of Self-Harm in Children and Adolescents
Nindy Adhilah,
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Yunias Setiawati
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Journal of korean Academy of Child and Adolescent Psychiatry,
Journal Year:
2025,
Volume and Issue:
36(2), P. 47 - 53
Published: April 1, 2025
Self-harm
is
a
prevalent
phenomenon
among
children
and
adolescents,
its
incidence
has
increased
over
time.
This
behavior
often
maladaptive
coping
mechanism
caused
by
difficulties
with
emotional
regulation.
in
adolescents
predictor
of
future
suicide
attempts
requires
comprehensive
management.
study
reviewed
current
holistic
management
self-harm
adolescents.
By
synthesizing
evidence-based
practices,
this
shows
that
should
include
the
recognition
risk
factors
for
suicidal
behavior,
early
detection,
pharmacological
non-pharmacological
therapies,
prevention
programs
at
all
levels.
aimed
to
increase
awareness
encourage
participation
from
societal
levels,
including
schools
policymakers,
handling
Language: Английский
The Association Between Internet Addiction and Non‐Suicidal Self‐Injury Among Adolescents: A Meta‐Analysis
Journal of Adolescence,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 28, 2025
Language: Английский
Mechanisms of microbial-gut-brain axis modulation by electroconvulsive therapy in the treatment of depression
Jiaming Ji,
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Jun Guo,
No information about this author
Jirong Yang
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et al.
Anesthesiology and Perioperative Science,
Journal Year:
2025,
Volume and Issue:
3(2)
Published: May 7, 2025
Abstract
Purpose
The
present
study
aims
to
evaluate
the
effects
of
electroconvulsive
therapy
(ECT)
on
depressive
behaviors.
In
addition,
we
explore
mechanisms
by
which
ECT
alters
composition
and
functioning
gut
microbiota
through
microbiota-gut-brain
axis.
Methods
A
depression
model
in
mice
was
established
using
chronic
unpredictable
mild
stress.
were
divided
into
three
groups:
control,
depression,
ECT-treated.
Depressive
behaviors
assessed
a
series
behavioral
tests,
including
monitoring
body
weight,
open
field
sucrose
preference
forced
swim
tests.
Histological
microcirculatory
assessments
brain
tissues
conducted
hematoxylin
eosin
(H&E)
staining,
Nissl
staining
immunofluorescence
methodology
along
with
laser
speckle
contrast
imaging.
inflammatory
cytokines
Tumor
Necrosis
Factor-
α
(TNF-
),
Interleukin-6
(IL-6)
Interleukin-1
β
(IL-1
)
quantified
enzyme-linked
immunosorbent
assay.
Metagenomic
sequencing
employed
diversity
abundance
microbiota.
Results
significantly
improved
as
evidenced
increased
weight
decreased
immobility
time
H&E
indicated
substantial
reduction
inflammation
while
revealed
restoration
neuronal
morphology
following
treatment.
Furthermore,
analysis
showed
elevated
c-Fos
expression
hippocampal
region
(
P
<
0.05).
Assessments
demonstrated
significant
reductions
TNF-
,
IL-6,
IL-1
levels
group.
metagenomic
that
enhanced
diversity,
particularly
restoring
Bacteroides
Verrucomicrobia
Conclusion
exerts
its
antidepressant
modulating
enhancing
functionality
gut-brain
Language: Английский
Metabolic Perturbations Associated with both PFAS Exposure and Perinatal/Antenatal Depression in Pregnant Individuals: A Meet-in-the-Middle Scoping Review
Himal Suthar,
No information about this author
Roselyn Tanghal,
No information about this author
Lida Chatzi
No information about this author
et al.
Current Environmental Health Reports,
Journal Year:
2024,
Volume and Issue:
11(3), P. 404 - 415
Published: June 19, 2024
Depression
during
the
perinatal
or
antenatal
period
affects
at
least
1
in
10
women
worldwide,
with
long
term
health
implications
for
mother
and
child.
Concurrently,
there
is
increasing
evidence
associating
maternal
exposure
to
per-
poly-fluoroalkyl
substances
(PFAS)
adverse
pregnancy
outcomes.
We
reviewed
body
of
examining
both
associations
between
PFAS
perturbations
metabolome,
metabolome
perinatal/antenatal
depression.
Through
this,
we
sought
explore
existing
as
a
potential
mediation
pathway
linking
Language: Английский