COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis (Preprint) DOI Creative Commons

Tahani Al Rahbeni,

Prakasini Satapathy, Ramaiah Itumalla

et al.

Published: Nov. 21, 2023

BACKGROUND The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization. OBJECTIVE This umbrella review synthesizes findings from systematic reviews meta-analyses provide insights into perceptions on across diverse populations regions. METHODS We conducted a literature search major databases identify meta-analysis that reported hesitancy. AMSTAR-2 (A Measurement Tool Assess Systematic Reviews) criteria were used assess methodological quality included reviews. Meta-analysis was performed using STATA 17 with random effect model. data synthesis is presented in table format via narrative. RESULTS Our inclusion met by 78 published between 2021 2023. analysis revealed moderate rate 63% (95% CI 0.60%-0.67%) general population, significant heterogeneity (<i>I</i><sup>2</sup> = 97.59%). Higher rates observed among health care workers individuals chronic diseases, at 64% 0.57%-0.71%) 69% 0.61%-0.76%), respectively. However, lower noted pregnant women, 48% 0.42%-0.53%), parents consenting for their children, 61.29% 0.56%-0.67%). pooled 32% 0.25%-0.39%) population. assessment 19 high-quality, 38 moderate-quality, 15 low-quality, 6 critically low-quality meta-analyses. CONCLUSIONS presence globally, emphasizing necessity population-specific, culturally sensitive interventions clear, credible information dissemination foster acceptance. disparities accentuate need continuous research understand evolving address unique concerns needs populations, thereby aiding formulation effective inclusive strategies. CLINICALTRIAL PROSPERO CRD42023468363; https://tinyurl.com/2p9kv9cr

Language: Английский

COVID-19 vaccine acceptance and its association with knowledge and attitude among patients with chronic diseases in Ethiopia DOI Creative Commons
Tilahun Degu Tsega, Abebaw Molla,

Tadesse Miretie Dessie

et al.

Human Vaccines & Immunotherapeutics, Journal Year: 2024, Volume and Issue: 20(1)

Published: May 17, 2024

COVID-19 vaccine acceptance is crucial for patients with chronic diseases, but previous studies in Ethiopia have yielded inconsistent and inconclusive findings. To fill this gap, we conducted a systematic review meta-analysis following established guidelines. Our search included relevant articles published between 2019 2023 from various sources. We assessed study heterogeneity publication bias, performed subgroup sensitivity analyses. findings indicate that the rate among diseases was 55.4%. also found good knowledge favorable attitude toward were positively associated rate. Based on these results, recommend healthcare professionals, policymakers, guide developers should work more to address relatively low Improving further about vaccines crucial. Future research include community-based qualitative enhance our understanding of acceptance.

Language: Английский

Citations

2
New pedagogical tools for vaccine education: preparing future healthcare workers for the next pandemic DOI Creative Commons
Sylvain Gautier, Mia-Marie Hammarlin, Edit Paulik

et al.

BMC Medical Education, Journal Year: 2024, Volume and Issue: 24(1)

Published: Nov. 14, 2024

Vaccine hesitancy (VH) is an issue for healthcare students, influenced by safety concerns and misinformation. The need better communication training understanding sociocultural factors in VH was highlighted a European University Alliance seminar. Practical exercises like simulation role-playing, interprofessional collaboration, digital literacy may improve vaccine education.

Language: Английский

Citations

2
Investigation and Modeling of the Variables of the Decision to Vaccinate as the Foundation of an Algorithm for Reducing Vaccination Reluctance DOI Creative Commons
Daniela Cîrnaţu, Silviu Gabriel Szentesi, Lavinia Denisia Cuc

et al.

Systems, Journal Year: 2023, Volume and Issue: 11(5), P. 220 - 220

Published: April 26, 2023

The purpose of this study is to examine the factors that influence vaccination options, including against COVID-19, in order develop a management algorithm for decision-makers reduce reluctance. This paper’s primary objective empirically determine relationships between different variables correlate non-vaccination behavior target population, as well implications public health and situational strategies future intentions. We created questionnaire investigate personal approach disease prevention measures general particular. Using SmartPLS, load developing an manage reluctance were calculated. results shows status individual determined by their vaccine knowledge. evaluation itself influences choice not vaccinate. There connection external influencing decision vaccinate clients’ motives. plays substantial part individuals protect themselves vaccination. External on with agreement/disagreement COVID-19 immunization, but there no correlation online activity outside refusal or opinion general.

Language: Английский

Citations

6
COVID-19 vaccine hesitancy in Turkey: A systematic review and meta-analysis DOI Creative Commons
Buğra Taygun Gülle, Meryem Merve Ören,

Tuba Dal

et al.

Epidemiology and Infection, Journal Year: 2023, Volume and Issue: 151

Published: Jan. 1, 2023

Abstract This systematic review and meta-analysis aims to estimate the prevalence of coronavirus disease 2019 (COVID-19) vaccine hesitancy in Turkey, which can aid future health policies strategies. A comprehensive search was conducted on various databases using keywords related COVID-19 Turkey. Quality assessment performed Joanna Briggs Institute (JBI) checklist for studies. Data extraction conducted. The random effect model (DerSimonian Laird method) used pooled data analysis (95% confidence interval [CI]). total 1,072 articles were identified. After removing duplicates excluding articles, 61 remained bias assessment. Among these, 19 with low risk included meta-analysis. Total population 15,164, 30.5% Cl: 24.3–36.8%). Prevalence found be 39.8% 31.4–48.2%) studies before initiation vaccination, while after commencement 20.4% 12.9–28%). We suggest conducting high-quality different populations understand level hesitancy, as many previous have mainly focused healthcare workers students, rest community-based studies, generally shown high bias. Also, we that early vaccination reduce hesitancy.

Language: Английский

Citations

6
COVID-19 vaccination intention among internally displaced persons in complex humanitarian emergency context, Northeast Nigeria DOI Creative Commons
Saheed Gidado,

Melton Musa,

Ahmed Ibrahim Ba’aba

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(8), P. e0308139 - e0308139

Published: Aug. 30, 2024

Internally displaced persons (IDPs) are at high risk for COVID-19 transmission because of congested and unsanitary living conditions. vaccination is essential to build population immunity prevent severe disease among this population. We determined the prevalence factors associated with intention accept vaccine IDPs in Northeast Nigeria. This cross-sectional study, conducted during July-December 2022, included 1,537 unvaccinated from 18 camps. performed a complex sample survey analysis described participants' characteristics weighted descriptive statistics. fitted logistic regression models computed adjusted odds ratios 95% confidence intervals identify vaccine. Of IDPs, 55.4% were 18-39 years old, 82.6% females, 88.6% had no formal education. Among them, 63.5% (95% CI: 59.0-68.1) expressed who intended reject vaccine, 42.8% provided reason, 35.3% misconceptions, 9.5% reported safety concerns, 7.4% felt need. perceived as (Adjusted Odds Ratio (AOR) = 2.31, [95% 1.35-3.96]), effective (AOR 4.28, 2.46-7.44]) resided official camps 3.29, 1.94-5.56]) more likely However, 2 kilometers or farther nearest health facility 0.34, 0.20-0.58]) less Intention was suboptimal. To improve acceptance population, education communication should be intensified counter misinformation, strengthen confidence, shape perception severity, focusing on unofficial Appropriate interventions deliver vaccines remote households ramped up.

Language: Английский

Citations

1
Understanding the COVID-19 vaccine uptake, acceptance, and hesitancy in Ethiopia and Tanzania: a scoping review DOI Creative Commons
Esayas Kebede Gudina, Florida Muro, Norman J. Kyala

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Nov. 11, 2024

The development and implementation of COVID-19 vaccines have been a breakthrough in controlling the pandemic. However, vaccination coverage most low-income countries remains very low due to critical vaccine shortage profound hesitancy. In this scoping review, we aimed assess uptake, acceptance, hesitancy Ethiopia Tanzania.

Language: Английский

Citations

1
Acceptance‐Hesitancy of COVID‐19 Vaccination and Factors Affecting It in Adults: Systematic Review Study DOI Creative Commons

Atieh Darbandi,

Maryam Koupaei,

Parisa Kiani

et al.

Immunity Inflammation and Disease, Journal Year: 2024, Volume and Issue: 12(11)

Published: Nov. 1, 2024

ABSTRACT Background Despite the advent of vaccines against COVID‐19, there is considerable variation in acceptance and hesitancy towards vaccination program across different countries. The objective this study was to ascertain prevalence regarding use vaccine novel coronavirus, also known as identify factors that influence these attitudes. Materials Methods All cross‐sectional studies were retrieved from PubMed databases, Web Science ISI, Scopus, Cochrane Library. Papers published English between 2 November 2019 23 May 2023 subjected further assessment based on their title, abstract, main text, with a view ensuring relevance present study. Results Following an exhaustive investigation, 59 selected for screening systematic review. most frequently employed method data collection online survey. sample comprised 59.12% women 40.88% men, ages ranging 16 78 years. proportion individuals accepting ranged 13% 96%, while those exhibiting 0% 57.5%. primary reasons COIVD‐19 heightened perception risk associated virus general trust healthcare system. cited context ongoing pandemic include concerns about potential dangers vaccines, rapid pace development, possibility adverse effects (such infertility or death), assumption they have been designed inject microchips. Discussion A variety socio‐demographic are implicated determining rate acceptance. number identified influencing These high income, male gender, older age, marriage, presence children who vaccinated do not chronic diseases, education, health insurance coverage. Conclusion Eliminating increasing crucial factor should be addressed through various means collaboration regulatory organizations.

Language: Английский

Citations

1
A Case of Intractable Hypophosphatemia in a Patient with Guillain-Barré Syndrome and Encephalitis after SARS-CoV-2 Infection DOI
Yawen Zheng, Yuanyuan Hou,

Ming-Zhu Qi

et al.

Endocrine Metabolic & Immune Disorders - Drug Targets, Journal Year: 2024, Volume and Issue: 24(11), P. 1346 - 1350

Published: Feb. 5, 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection attacks the and nervous systems. Among patients with SARS-CoV-2 infection, cases simultaneous central peripheral system damage are rare, those intractable hypophosphatemia hypokalemia complicating former have not been reported yet.

Language: Английский

Citations

0
Trends and cross-country disparity in the burden of COVID-19 between 2020 and 2021: a systematic analysis for the Global Burden of Disease Study 2021 DOI
Qiuying Chen,

Lanyue Pan,

Yuan Zhan

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 24, 2024

Abstract Background Coronavirus disease 2019 (COVID-19) has led to extensive repercussions on global health and economic systems. In this study, we aim provide an analysis of global, national, regional COVID-19 incidence, mortality, disability-adjusted life years (DALYs) for the 2020 2021. Methods Data DALYs, mortality were derived from Global Burden Disease Study 2019. The data carefully estimated presented in both numerical values age-standardized rates (ASRs) per 100,000 individuals, inclusive 95% uncertainty intervals (UI). study further stratified burden by age, gender, sociodemographic index (SDI), system infrastructure. Additionally, correlation between ASR SDI was examined. Findings There marked disparities across various countries regions Globally, number DALYs death showed increasing trend 2021, particularly with lower less robust healthcare Men exhibited higher numbers ASRs death. elderly experienced despite having lowest incidence rates. Furthermore, a significant negative observed 21 204 countries. Conclusion This highlights pronounced escalation elderly, males, those developed systems being disproportionately affected. A comprehensive understanding epidemiology is essential devising strategies mitigate disease's impact.

Language: Английский

Citations

0
Safety observation of COVID-19 inactivated vaccine in immature mice DOI
Jingxuan Zhou, Yingyan Han,

Xiaoyuan Huang

et al.

Immunopharmacology and Immunotoxicology, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 7

Published: Nov. 11, 2024

To investigate the safety of COVID-19 inactivated vaccine in immature mice.

Language: Английский

Citations

0