Why Some People Are Hesitant to Receive COVID-19 Boosters: A Systematic Review

Tropical Medicine and Infectious Disease, Journal Year: 2023, Volume and Issue: 8(3), P. 159 - 159

Published: March 5, 2023

As the COVID-19 pandemic continues and transitions to an endemic stage, booster vaccines will play important role in personal public health. However, convincing people take boosters be a key obstacle. This study systematically analyzed research that examined predictors of vaccine hesitancy. A search PubMed, Medline, CINAHL, Web Science, Scopus uncovered 42 eligible studies. Globally, average vaccination hesitancy rate was 30.72%. Thirteen factors influencing emerged from literature: demographics (gender, age, education, income, occupation, employment status, ethnicity, marital status), geographical influences (country, region, residency), adverse events, perceived benefit/efficacy, susceptibility, severity, prior history infection, recommendations, health knowledge information, skepticism/distrust/conspiracy theories, type. Vaccine communication campaigns interventions for COVID should focus on confidence, complacency, convenience.

Language: Английский

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A Systematic Review on Sociodemographic, Financial and Psychological Factors Associated with COVID-19 Vaccine Booster Hesitancy among Adult Population

Vaccines, Journal Year: 2023, Volume and Issue: 11(3), P. 623 - 623

Published: March 9, 2023

While considerable evidence supports the safety and efficacy of COVID-19 vaccines, a sizable population expresses vaccine hesitancy. As per World Health Organization, hesitancy is one top 10 hazards to global health. Vaccine varies across countries, with India reporting least was higher toward booster doses than previous shots. Therefore, identifying factors determining hesitance (VBH) sine qua non successful vaccination campaign.This systematic review followed Preferred Reporting Items for Systematic Reviews Meta-analysis (PRISMA) 2020 standards. A total 982 articles were pooled from Scopus, PubMed Embase, while 42 that addressed VBH finally included further analysis.We identified responsible divided them into three major groups: sociodemographic, financial, psychological. Hence, 17 stated age be factor hesitancy, most reports suggesting negative correlation between fear poor outcomes. Nine studies found females expressing greater males. Trust deficit in science (n = 14), concerns about 12), lower levels regarding infection 11), worry side effects 8) also reasons Blacks, Democrats, pregnant women showed high Few have income, obesity, social media, living vulnerable members as influencing study 44.1% towards could attributed dominantly low rural origin, previously unvaccinated status, or individuals. However, two other Indian reported lack availability slots, trust government, doses.Many confirmed multifactorial nature VBH, which necessitates multifaceted, individually tailored interventions address all potentially modifiable factors. This chiefly recommends strategizing campaign by evaluating appropriate communication (at both individual community levels) benefits risk losing immunity without them.

Language: Английский

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Global disparities in COVID-19 vaccine booster dose (VBD) acceptance and hesitancy: An updated narrative review

Vaccine X, Journal Year: 2024, Volume and Issue: 18, P. 100480 - 100480

Published: March 23, 2024

The global deployment of COVID-19 vaccine booster dose (VBD) has been recognized as a promising therapeutic alliance to provide repeated immunity against the arrival new variants. Despite scientific evidence supports effectiveness periodic doses, reluctance continues thrive. This narrative review aimed examine doses acceptance and summarize an up-to-date assessment potential antecedents associated with VBD acceptance. A comprehensive search was performed in several reputable databases such Medline (via PubMed), Scopus, Google scholar, Web Science from June 10th, 2023, August 1st, 2023. All relevant descriptive observational studies on hesitancy were included this review. total fifty-eight (58) included, Asia representing highest count thirty-one (53 %) studies, Europe eleven (19 %), United States nine (16 other regions (Africa multi-ethnic) seven (12 %). Worldwide, pooled rate 77.09 % (95 CI: 76.28–78.18), willingness (n) = 164189, sample (N) 212,990. lowest reported American regions, respectively, 85.38 85.02–85.73, 32,047, (N 37,533) vs. 66.92 66.56–67.4), 29335, 43,832. However, multi-ethnic areas moderately high 79.13 78.77–79.23, 93,994, 11,8779) 72.16 71.13–72.93, 9276, 12,853), respectively. most common key across countries "equal safety", "efficacy", "effectiveness", post-vaccination "side effects", "community protection" "family protection", "risk-benefit ratio", necessity", "trust, "variants control". Disparities uptake observed globally, rates found Europe, regions. Multiple including safety, efficacy, side effects hesitancy.

Language: Английский

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Insulin therapy adherence and its associated factors among diabetic patients in a Ghanaian primary care hospital

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0312094 - e0312094

Published: Jan. 24, 2025

Background Diabetes mellitus (DM) is a global health problem. Adherence to intensive insulin therapy necessary achieve better glycemic control in types 1 and 2 DM. This study aimed evaluate the extent of adherence therapy, its predictors identify barriers adherence. Method was cross-sectional survey among adult (≥18 years) diabetic patients who are currently using insulin, either alone or combination with an oral antidiabetic regimen, seeking primary care at Kwame Nkrumah University Science Technology Hospital Ghana. A total one hundred eight-six were conveniently sampled, interviewed. Insulin determined Medication Reporting Scale-5. Descriptive statistics, chi-square test independence, multiple logistic regression analysis performed STATA version 14 (StataCorp, TX USA). Results The majority interviewed over 60 years (40.32%); female (61.83%); married (68.82%); had completed secondary education (48.39%). 67.20% adherent therapy. level associated age (p = 0.020), marital status 0.001), employment 0.012), type DM (p<0.001), regular follow-up 0.007) comorbidities 0.002) only predicted by (aOR 14.82 C.I 1.34–163.50, p-value 0.028). Conclusion our population suboptimal, which concern considering increased risk complications. assessment counselling healthcare professionals address poor must be continually undertaken optimal control. Impact findings on practice statements Continuous offered all diabetes as part their ambulatory help improve outcomes. Using Scale-5 determine patient levels easy-to-use inexpensive method; however, it should used caution due potential for misclassification. Efforts made provide appropriate strategies deal clinics individualized comprehensive reduce

Language: Английский

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Attitude and Acceptance towards COVID-19 Booster Doses among Literacy Advantaged Population in Pakistan: A Cross-Sectional Study

Vaccines, Journal Year: 2023, Volume and Issue: 11(7), P. 1238 - 1238

Published: July 14, 2023

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has affected billions of lives and is expected to impose a significant burden on the economy worldwide. Vaccination only way prevent infection. However, convincing people get themselves vaccinated challenging in developing countries such as Pakistan. Therefore, cross-sectional questionnaire-based study was conducted (n = 982 participants) all over Pakistan evaluate perception, knowledge, attitude, acceptance general public towards SARS-CoV-2 vaccine, general, booster dose SARS-CoV-2, particular. The highest number participants were from province Punjab (84.5%), followed by Islamabad (3.8%), Sindh (3.7%), Khyber Pakhtunkhwa (2.7%), Baluchistan (2.6%), Gilgit Baltistan (1.4%), Azad Jammu Kashmir (1.4%). A total 915 against COVID-19, out which 62.2% received one dose, double doses (25.5%) single vaccine shots (12.3%). (85.8%), (3.9%), (2.8%); (2.6%); (2.3%); Gilgit-Baltistan (1.3%); Azad, Jammu, (1.2%). Among individuals, 71.4% unemployed, 27.4% employed (653), 1.2% retired service. no association observed among genders educational levels regard vaccine. outcomes revealed that increased vaccines associated with intent personal family protection. Moreover, individuals low socioeconomic status pregnant females showed least inoculation. also decline trend accepting children.

Language: Английский

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Acceptance of COVID-19 vaccine booster dose among the people of Bangladesh: A cross-sectional study

Heliyon, Journal Year: 2023, Volume and Issue: 9(11), P. e22215 - e22215

Published: Nov. 1, 2023

Vaccine booster dose (VBD) provides a potential therapeutic alliance in preventing breakthrough infection and new variant's arrival while preserving long-lasting host immunity. This study aimed to analyze COVID-19 VBD willingness identified the key determinants of acceptance among general people Bangladesh. survey-based applied quantitative research paradigm. A validated, anonymous, multi-item questionnaire was adopted through theoretical review pertinent literature on topic. Data were collected between August 2022─October 2022, sampling done randomly. total 704 individuals invited via face-to-face interview approach; however, 13.8 % them declined give consent, which resulted participation 607 respondents. The main outcome measure willingness. Binary logistic regression analysis conducted rationalize study's objectives. pooled vaccine rate 70.0 (95 confidence Interval [CI]: 67─73) Bangladeshi people. An binary revealed that, out 14 factors, "efficacy", "repeated immunity", "communication", "trust" showed highly significant positive association (adjusted odds ratio [aOR ] = 2.151 95 CI: 1.391─ 3.508, aOR 2.033 1.299─ 3.181, 2.552 1.557─4.183 respectively, p<0.01), "equal safety", "risk-benefit ratio" "community protection" had (aOR 1.739 1.070─2.825, 1.712 1.116─2.627, 1.628 1.395─0.998, p<0.05) with acceptance. However, post-vaccination "side effects" negative 0.393 0.237─0.674, p<0.01) associations accepting found 1.26, it insignificant (p>0.05) Chi-squared test. expressed moderately high level response attitude towards is an this study, regardless circumstances, as far safety, efficacy, perceived health benefits, communication, trust, community resistance are concerned. Post-vaccination side effects fear primary reason for skepticism well barrier administering shots. will be boosted when mass effectively communicated vaccine's data become more available publicly.

Language: Английский

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COVID-19 Vaccine Booster Hesitancy (VBH) among Healthcare Professionals of Pakistan, a Nationwide Survey

Vaccines, Journal Year: 2022, Volume and Issue: 10(10), P. 1736 - 1736

Published: Oct. 17, 2022

Background: The waning vaccine immunity and emergence of new variants SARS-CoV-2 led health authorities across the globe to administer booster doses (BDs) COVID-19 vaccine. Hence, current study aimed assess hesitancy (VBH) amongst Pakistani healthcare professionals (HCPs). Methods: A nationwide survey-based was carried out from April 2022 May 2022. online self-administered questionnaire utilized collect data regarding demographics (age, gender, marital status, profession, residential area, province), infection history (infection history, onset, clinical severity disease), previous vaccination (type number doses), attitudes towards BDs (acceptance, rejection, hesitancy), psychological drivers VBH (perceived effectiveness, safety, risk/benefit ratio, type preference). We assessed association between dependent variable participants, independent variables (demographics, vaccination, VBH), by using Chi-square test/Fisher exact test. Results: Among 1164 51.4% were male, 80.4% medical professionals. half participants (52.1%) agreed take BD or had already taken it, while rest them refused (34.7%) hesitated (24.2%) it. These significantly associated (p < 0.001) with divers about BD. Conclusion: This revealed that HCPs hesitant concerns efficacy, risk/benefits ratio vaccine’s To eliminate hesitancy, in HCPs, certain educational strategies should be implemented address HCPs.

Language: Английский

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COVID-19 Booster Vaccine Hesitancy among Hemodialysis Patients in Saudi Arabia Using the Health Belief Model: A Multi-Centre Experience

Vaccines, Journal Year: 2022, Volume and Issue: 11(1), P. 95 - 95

Published: Dec. 31, 2022

Vaccination hesitance for the COVID-19 booster dosage among hemodialysis patients is an important barrier in reducing morbidity and mortality linked to infection. Hence, this study aimed explore predictors of third (booster) dose vaccine intention CKD on from Kingdom Saudi Arabia (KSA).This was a multi-center cross-sectional conducted at four dialysis centers KSA 13 February 2022 21 June 2022. The data collected by nephrologist charge unit using structured questionnaire, which consisted parts; socio-demographic clinical variables, questions about infection subjective assessment health state, vaccination confidence vaccines preferences, belief model. population 179 patients.Participants had conflicting beliefs their vulnerability severity Study participants expressed positive advantages dose, reported less perceived obstacles receiving vaccine. influence cues action high. A total 140 (78.2%) receive dose. Patients who poor self-rating status substantially higher definite take according chi-square test (11.16, df = 3, p 0.01). There significant association between constructs HBM model intention. Marital (OR 1.67, CI 1.07-2.58) found be strongest Confidence locally manufactured 0.33, 0.17-0.60), education 0.62, 0.41-0.93), rating 0.43 0.25-0.74) were correlates having no vaccination.HBM significantly associated with intention, can considered while planning policies promote patients. results could utilized drafting improve uptake population.

Language: Английский

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Jeelo Dobara (Live Life Again): a cross-sectional survey to understand the use of social media and community experience and perceptions around COVID-19 vaccine uptake in three low vaccine uptake districts in Karachi, Pakistan

BMJ Open, Journal Year: 2023, Volume and Issue: 13(1), P. e066362 - e066362

Published: Jan. 1, 2023

Objective To gather preliminary insights through formative research on social media usage, and experiences, attitudes perceptions around COVID-19 vaccination in three high-risk, underserved districts Karachi, Pakistan. Design Cross-sectional mixed-method design. Participants 392 adults (361 surveys 30 in-depth interviews (IDI)) from South, East Korangi Main outcome measures Social usage knowledge, perception behaviour towards infection vaccination. Results Using was associated with an increased probability of getting vaccinated by 1.61 units. Most the respondents (65%) reported using media, mainly to watch videos and/or keep touch family/friends. 84.76% knew while 88.37% about vaccination, 71.19% vaccine receipt; reasons vaccinate included belief that vaccines protect virus, being mandatory for work. However, only 56.7% believed they were at risk disease. Of 54 unvaccinated individuals, 27.78% did not as believe COVID-19. Despite this, 78.38% scored high confidence. In IDIs, most vaccines: ‘This will create immunity your body. Therefore, I think we should get vaccinated’, over half how spreads. considered a serious public health problem thought it important people vaccinated. there low-risk self little felt contracting Conclusion With our conflicting results regarding confidence, is, coverage but low self, is likely more result mandates coercion than true Our findings imply interactive could be valuable fostering provaccine sentiment.

Language: Английский

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Differences in non-positive intention to accept the COVID-19 booster vaccine between three countries in the cross-border region Meuse-Rhine Euroregion: The Netherlands, Belgium, and Germany

Vaccine X, Journal Year: 2023, Volume and Issue: 14, P. 100306 - 100306

Published: April 20, 2023

COVID-19 booster vaccination has shown to add the protection against infection with SARS-CoV2 and subsequent severe disease. This longitudinal cross-border study aimed identify factors associated vaccine intentions in an initially vaccinated adult population living Meuse-Rhine Euroregion (EMR; including Netherlands, Belgium, Germany) differences between countries. Data collection took place autumn of 2021 consisted online questionnaires sent a random sample based on governmental registries. from 3,319 fully partially adults were used examine determinants non-positive intention for (i.e., uncertain or do not want), using multivariable logistic regression analyses weighted by age group, sex, country. Compared German residents, Dutch residents (OR = 2.4) Belgian 1.4) more likely be want receive September-October 2021. Factors independently female sex 1.6), absence comorbidities 1.3), time since last less than 3 months ago those being 3.6), negative experience communication measures 2.2), regarding as ineffective 1.1). Results indicate that differ countries cross border Euroregion. Non-positive is prevalent all three EMR, but different extent, this study. Cross-border collaboration sharing information knowledge about strategies could play role limiting impact COVID-19.

Language: Английский

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