Background:
Serological
studies
on
the
association
between
disease
severity
and
humoral
immunity
against
SARS-CoV-2
during
first
wave
of
COVID-19
pandemic
remains
inconclusive.
This
study
focused
immune
responses
antigen-specific
isotypespecific
antibodies
from
infected
patients
with
different
prior
to
implementation
national
vaccination
program
in
Philippines.Methods:
analyzed
177
biobank
serum
samples
67
hospitalized
adult
RT-PCR-confirmed
pandemic.
Immunoglobulin
(Ig)
G,
IgM,
IgA
S1,
S2,
RBD,
N
proteins,
as
well
IgG
human
ACE2,
were
determined
by
enzyme-linked
immunosorbent
assay
(ELISA).
Serum
neutralization
capacity
was
1)
ACE2-RBD
binding
inhibition
2)
pseudovirus
assay.
The
relationship
various
clinical
parameters
determined.Findings:
IgG,
antibody
associated
within
two
weeks
after
symptom
onset.
IgM
response
positively
correlated
inflammatory
markers
ferritin
C-reactive
protein.
IgM-N
particular
shown
predict
in-hospital
mortality.
However,
patient
sera
lacked
neutralizing
activity
Wuhan
strain.
On
other
hand,
anti-ACE2
detected
cohort,
levels
not
or
markers.Interpretation:
Most
early
had
high
SARSCoV-2
but
low
capacity.
Moreover,
role
implications
ofdetectable
ACE2
need
further
investigation.Funding:
did
receive
any
funding.Declaration
Interest:
We
declare
no
competing
interests.Ethical
Approval:
conducted
approval
University
Philippines
Manila
Institutional
Ethics
Review
Board
(UPMREB
2020-0801-01).
Medicine Advances,
Journal Year:
2024,
Volume and Issue:
2(2), P. 144 - 164
Published: June 1, 2024
Abstract
Background
The
incidence
of
lung
cancer
combined
with
pulmonary
tuberculosis
has
been
increasing,
but
there
is
relatively
limited
published
literature
on
the
topic
(LC‐PTB)
from
a
bibliometric
perspective.
Therefore,
in
this
study,
we
aimed
to
quantitatively
analyze
LC‐PTB‐related
better
understand
current
status
field
and
identify
future
research
trends.
Methods
We
searched
for
articles
related
LC‐PTB
using
Web
Science
Core
Collection
(SCI‐E)
conducted
visual
analysis
publication
quantity,
countries,
institutions,
authors,
journals,
references,
keywords
software
(CiteSpace,
VOSviewer,
Scimago
Graphica).
Results
As
January
8,
2024,
total
460
publications
were
included
3705
retrieved
records.
number
increasing
almost
yearly,
most
China
(
n
=
123),
followed
by
United
States
77).
Taipei
Medical
University
contributed
11).
Jing‐Yang
Huang
Yung‐Po
Liaw
(eight
documents
each)
ranked
first
among
authors.
Journal
Thoracic
Oncology
was
productive
academic
journal
LC‐PTB.
aggregation
key
nodes
co‐citation
network
chronological
sequence
indicated
that
shifted
initial
hotspots
such
as
diseases,
bronchitis,
exposure
recent
areas,
including
immunotherapy,
immune
checkpoint
inhibitors,
nivolumab.
Conclusion
In
visualized
well
trends
methods,
providing
new
insights
into
differential
diagnosis
its
promoting
mechanisms.
Human Vaccines & Immunotherapeutics,
Journal Year:
2024,
Volume and Issue:
20(1)
Published: July 8, 2024
The
outbreak
of
the
COVID-19
has
seriously
affected
whole
society,
and
vaccines
were
most
effective
means
to
contain
epidemic.
This
paper
aims
determine
top
100
articles
cited
frequently
in
analyze
research
status
hot
spots
this
field
through
bibliometrics,
provide
a
reference
for
future
research.
We
conducted
comprehensive
search
Web
Science
Core
Collection
database
on
November
29,
2023,
identified
by
ranking
them
from
highest
lowest
citation
frequency.
In
addition,
we
analyzed
year
publication,
citation,
author,
country,
institution,
journal,
keywords
with
Microsoft
Excel
2019
VOSviewer
1.6.18.
Research
focused
vaccine
immunogenicity
safety,
hesitancy,
vaccination
intention.
Ukrainian Scientific Medical Youth Journal,
Journal Year:
2025,
Volume and Issue:
152(1), P. 55 - 60
Published: Feb. 25, 2025
this
bibliometric
evaluation
reviewed
forensic
serology
studies
from
2000
to
2023,
utilising
Scopus
records
song
guide
trends,
key
contributors,
and
impactful
research.
The
subject
showed
significant
growth,
with
201
documents
posted
at
a
four.89%
annual
boom
price.
Major
members
consist
of
Virginia
Commonwealth
University
fantastic
researchers
like
Hanson
EK
Juusola
J.
highlight
diverse
file
kinds
influential
papers,
emphasizing
ongoing
advancements
the
want
for
global
collaboration.
Limitations
encompass
reliance
on
ability
language
bias.
Overall,
study
demonstrates
dynamic
progress
in
significance
continued
Gynecological Endocrinology,
Journal Year:
2025,
Volume and Issue:
41(1)
Published: Feb. 28, 2025
Objectives:
Premature
ovarian
insufficiency
(POI)
is
a
serious
condition
that
affects
women
worldwide,
In
recent
years,
the
number
of
research
publications
on
POI
has
increased
over
last
decades
because
advancement
cutting-edge
in
gynecology
and
deepening
disciplinary
interactions.
At
same
time,
there
more
urgent
need
to
systematically
analyze
review
existing
studies
generalize
paradigm
structure
field
under
technological
changes.
Cancer Nanotechnology,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: April 25, 2024
Abstract
Background
Breast
cancer
is
the
most
common
cause
of
cancer-related
deaths
among
women
globally
and
deadly
illness
for
them.
New
advances
in
nanotechnology
have
led
to
development
strategies
intended
target
breast
cells
more
precisely
while
causing
least
amount
damage
healthy
cells.
We
retrieved
articles
about
nanomaterials
diagnosis
treatment
from
Web
Science
Core
Collection
(WoSCC)
database
between
2008
2023.
Our
research
aims
assess
publications
on
use
predict
future
directions.
Results
A
total
457
papers
were
discovered
various
nations,
with
China
being
primary
source
United
States
having
highest
H
index.
The
number
this
discipline
increasing
an
annual
basis.
Egyptian
Knowledge
Bank
important
center
sector.
International
Journal
Nanomedicine
has
papers,
Kesharwani
P
frequently
referenced
author.
quoted
article
was
written
by
Miele,
Evelina
India
2009.
Topics
such
as
drug
delivery
may
be
emerging
areas
research.
Conclusion
findings
that
medication
will
become
a
significant
area
future,
provide
valuable
references
scholars
investigating
role
cancer.
Journal of Pain Research,
Journal Year:
2023,
Volume and Issue:
Volume 16, P. 269 - 285
Published: Jan. 1, 2023
Dysmenorrhea
is
the
most
common
gynecological
condition
among
women
of
childbearing
age
and
remains
a
challenging
public
health
issue.
This
study
aimed
to
visualize
profiles
hotspots
in
dysmenorrhea
research
through
bibliometric
analysis
deepen
understanding
knowledge
this
field.Articles
reviews
on
published
from
2000
2021
were
collected.
We
summarized
standard
indicators.
Publications
systematically
assessed
terms
country,
institution,
author,
journal,
reference,
keywords
using
Citespace,
VOSviewer,
Bibliometric,
an
online
platform.
Besides,
correlation
analyses
country-specific
characteristics
indicators
performed.3407
publications
included.
Dysmenorrhea-related
have
been
increasing
steadily
annually.
China
United
States
productive
academically
influential
countries,
respectively.
Correlation
revealed
that
economic
power
essential
factor
influencing
scientific
activity.
However,
collaboration
remained
weak.
Natl
Yang
Ming
Univ
Vercellini
P
institution
A
significant
proportion
was
high-impact
journals
it
explored
at
multidisciplinary
level.
Current
topics
focus
two
primary
areas:
(1)
pathophysiology,
such
as
pathogenesis,
oxidative
stress,
functional
connectivity,
(2)
impacts,
quality
life,
burden,
depression,
exercise.Dysmenorrhea
has
received
extensive
attention
scholars
rapidly
evolving.
Improved
interdisciplinary
exploration
may
advance
field.
Public
pathophysiological
are
current
also
be
coming
years.
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(1), P. e0296521 - e0296521
Published: Jan. 5, 2024
Background
Evaluating
immune
responses
following
COVID-19
vaccination
is
paramount
to
understanding
vaccine
effectiveness
and
optimizing
public
health
interventions.
This
study
seeks
elucidate
individuals’
status
after
administering
a
second
dose
of
diverse
vaccines.
By
analyzing
through
serological
markers,
we
aim
contribute
valuable
insights
into
the
uniformity
performance.
Methods
A
total
80
participants
were
enrolled
in
this
study,
with
demographic
infection-related
data
collected
for
categorization.
Serum
samples
acquired
within
specified
timeframe,
SARS-CoV-2
IgM/IgG
rapid
tests
conducted.
Moreover,
CTLA-4
levels
measured
ELISA
assays,
allowing
us
assess
comprehensively.
The
divided
eight
groups
based
on
various
factors,
facilitating
multifaceted
analysis.
Results
outcomes
our
investigation
demonstrated
consistent
across
types
vaccines
administered
Iraq.
Statistical
analysis
revealed
no
significant
distinctions
among
categories.
In
contrast,
differences
observed
control
group
(non-infected/non-vaccinated,
infected/non-vaccinated)
infected/Pfizer,
non-infected/Pfizer,
infected/Sinopharm,
non-infected/sinopharm
(P
=
0.001,
<
0.023,
respectively).
suggests
that
these
exhibit
comparable
eliciting
an
response
participants.
Conclusions
conclusion,
study’s
results
underscore
lack
discriminatory
variations
between
different
utilized
uniform
signify
equitable
efficacy
performance
Despite
minor
quantitative
discrepancies,
do
not
hold
statistical
significance,
reaffirming
notion
serve
similar
purpose
conferring
protection
against
COVID-19.
Journal of Multidisciplinary Healthcare,
Journal Year:
2023,
Volume and Issue:
Volume 16, P. 3941 - 3957
Published: Dec. 1, 2023
Pregnant
women
are
highly
susceptible
to
periodontal
disease
due
changes
in
hormonal
and
immune
levels,
which
places
a
huge
burden
on
the
healthcare
system
requires
multidisciplinary
interventions.
This
study
aimed
assess
scientific
profile
research
trends
related
pregnancy
through
bibliometric
approach.Publications
about
from
2000
2022
were
extracted
Science
Citation
Index
Expanded.
The
knowledge
networks
of
countries,
institutions,
authors,
journals,
references,
keywords
this
field
constructed
using
Citespace,
VOSviewer,
Bibliometrix,
BIBLIOMETRIC.COM
platforms.
Furthermore,
correlations
between
characteristics
countries
number
or
impact
publications
analyzed.1162
original
studies
reviews
included.
There
was
trend
toward
increased
citations
field.
United
States
had
highest
academic
productivity
by
significant
margin,
while
correlation
analyses
indicated
that
economic
power
may
correlate
with
national
activity.
University
North
Carolina
Offenbacher
S
most
influential
institution
author,
respectively,
taking
center
stage
collaborative
networks.
However,
only
several
loose
connections
institutions
identified
global
network
analysis.
Six
top
ten
productive
journals
Q1
Journal
Report,
there
intensive
interaction
different
subfields,
such
as
immunology,
molecular
biology,
microbiology.
Frontier
topics
primarily
clustered
two
areas:
(1)
oral
microbiology,
microbiome,
bacteria,
Fusobacterium
nucleatum;
(2)
public
health,
quality
life,
outcomes,
obesity,
classification.Since
2000,
is
receiving
increasingly
widespread
attention
rapidly
evolving
at
level.
Oral
microbiological
pathogenesis
health
impact-related
deserve
more
exploration
be
future
direction
research.
Enhanced
Collaboration
interdisciplinary
communication
further
facilitate
progress
discipline.
Current Bioinformatics,
Journal Year:
2023,
Volume and Issue:
19(6), P. 551 - 570
Published: Oct. 11, 2023
Background::
Predicting
cardiac
arrest
is
crucial
for
timely
intervention
and
improved
patient
outcomes.
Machine
learning
has
yielded
astounding
results
by
offering
tailored
prediction
analyses
on
complex
data.
Despite
advancements
in
medical
expert
systems,
there
remains
a
need
comprehensive
analysis
of
their
effectiveness
limitations
prediction.
This
arises
because
are
not
enough
existing
studies
that
thoroughly
cover
the
topic.
Objective::
The
systematic
review
aims
to
analyze
literature
systems
prediction,
filling
gaps
knowledge
identifying
key
challenges.
Methods::
paper
adopts
PRISMA
methodology
conduct
37
publications
obtained
from
PubMed,
Springer,
ScienceDirect,
IEEE,
published
within
last
decade.
Careful
inclusion
exclusion
criteria
were
applied
during
selection
process,
resulting
utilizes
five
integrated
layers-
research
objectives,
data
collection,
feature
set
generation,
model
training
validation
employing
various
machine
techniques.
Results
Conclusion::
findings
indicate
current
frequently
use
ensemble
deep
methods
improve
predictions’
accuracy.
However,
they
lack
adequate
implementation
proper
pre-processing
Further
needed
address
challenges
related
external
validation,
implementation,
adoption
models
real
clinical
settings,
as
well
integrating
with
AI
technologies
like
NLP.
be
valuable
resource
both
novice
experienced
researchers,
insights
into
potential
future
recommendations.