Psychological factors associated with Long COVID: a systematic review and meta-analysis

EClinicalMedicine, Journal Year: 2024, Volume and Issue: 74, P. 102756 - 102756

Published: July 27, 2024

Language: Английский

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Looking at the Data on Smoking and Post-COVID-19 Syndrome—A Literature Review

Journal of Personalized Medicine, Journal Year: 2024, Volume and Issue: 14(1), P. 97 - 97

Published: Jan. 16, 2024

Long COVID is a recently described entity that responsible for significant morbidity and has consequences ranging from mild to life-threatening. The underlying mechanisms are not completely understood, treatment options currently limited, as existing data focus more on risk factors predictors. Smoking been reported factor poor outcomes of acute SARS-CoV-2 infection seems also play role in mediating post-COVID-19 symptoms. We aimed review relevant work addressing the interaction between smoking long order characterize smoking’s possibly identify new research directions. Methods: PubMed/MEDLINE database was searched using keywords ‘smoking’, ‘long COVID’, ‘post-acute COVID’ English-language articles published up October 2023. Results conclusions: From 374 initial hits, total 36 papers were deemed aim review. There variability concerning ways which tobacco usage quantified reported; still, there compelling evidence linking an increased developing manifestations post-acute-COVID disease. Some clinical conditions, such dyspnea, cardiovascular symptoms, cognitive or mental-health impairment, seem be relatively strongly associated with smoking, while connection upper-airway involvement less certain. available support recommending cessation tool prevention COVID.

Language: Английский

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Prevalence, predictors, and patient-reported outcomes of long COVID in hospitalized and non-hospitalized patients from the city of São Paulo, Brazil

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 11

Published: Jan. 22, 2024

Background Robust data comparing long COVID in hospitalized and non-hospitalized patients middle-income countries are limited. Methods A retrospective cohort study was conducted Brazil, including patients. Long diagnosed at 90-day follow-up using WHO criteria. Demographic clinical information, the depression screening scale (PHQ-2) day 30, compared between groups. If PHQ-2 score is 3 or greater, major depressive disorder likely. Logistic regression analysis identified predictors protective factors for COVID. Results total of 291 1,118 with COVID-19 were included. The prevalence 47.1% 49.5%, respectively. Multivariable logistic showed female sex (odds ratio [OR] = 4.50, 95% confidence interval (CI) 2.51–8.37), hypertension (OR 2.90, CI 1.52–5.69), > 6.50, 1.68–33.4) corticosteroid use during hospital stay 2.43, 1.20–5.04) as patients, while 2.52, 1.95–3.27) 3.88, 2.52–6.16) Conclusion prevalent both Positive 30 post-infection can predict Early helps health staff to identify a higher risk COVID, allowing an early diagnosis condition.

Language: Английский

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Longitudinal clinical phenotyping of post COVID condition in Mexican adults recovering from severe COVID-19: a prospective cohort study

Frontiers in Medicine, Journal Year: 2023, Volume and Issue: 10

Published: Aug. 24, 2023

Introduction Few studies have evaluated the presence of Post COVID-19 conditions (PCC) in people from Latin America, a region that has been heavily afflicted by pandemic. In this study, we describe frequency, co-occurrence, predictors, and duration 23 symptoms cohort Mexican patients with PCC. Methods We prospectively enrolled followed adult hospitalized for severe at tertiary care centre Mexico City. The incidence PCC was determined using questionnaires. Unsupervised clustering symptom co-occurrence Kaplan–Meier analyses persistence were performed. effect baseline clinical characteristics Cox regression models reported hazard ratios (HR). Results found amongst 192 PCC, respiratory problems most prevalent commonly co-occurred functional activity impairment. 56% had ≥5 persistent symptoms. Symptom probability 360 days 0.78. Prior SARS-CoV-2 vaccination infection during Delta variant wave associated shorter Male sex impairment Hypertension diabetes longer Previous accelerated recovery. Discussion our cohort, frequent (particularly neurocognitive ones) persistent. Importantly, prior resulted

Language: Английский

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Prevalence of depression, anxiety, stress, and suicide tendency among individual with long-COVID and determinants: A systematic review and meta-analysis

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0312351 - e0312351

Published: Jan. 28, 2025

Background While mental health alterations during active COVID-19 infection have been documented, the prevalence of long-term consequences remains unclear. This study aimed to determine symptoms—depression, anxiety, stress, and suicidal tendencies—and identify their trends associated risk factors in individuals with long-COVID. Methods We conducted a systematic literature search databases including PubMed, EMBASE, Scopus, CINAHL, Cochrane Library, Web Science, PsycINFO up August 2024, targeting observational studies published English. Study quality was assessed using structured standard tools. The primary outcome pooled depression, tendencies Secondary outcomes included these problems over time identification determinants. Results A total 94 eligible were analysis. estimates, regardless follow times duration, as follows: 25% (95%CI:22–28%; PI:1–59%); anxiety (adjusted via trim fill method), 23%(95%CI:21–25%;PI:2–35%); composite depression and/or (95%CI:23–27%;PI:2–51%); 26%(95%CI:13–39%;PI:1–69%); suicidality, 19%(95%CI:15–22%;PI:13–25%). results meta-regression analyses revealed statistically significant trend showing gradual decrease (RD = -0.004,P 0.022). Meta-regression indicated that being female younger age significantly higher symptoms. design setting did not contribute heterogeneity. Conclusion One-fourth individual long-COVID experience symptoms, which remain prevalent even two years post-infection despite slight decreasing trend. Factors such gender linked rates depression. These findings indicate need for ongoing screening early interventions mitigate psychological distress patients.

Language: Английский

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Post COVID-19 infection and quality of life of healthcare workers at Sahloul University Hospital of Sousse in Tunisia

Quality of Life Research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Language: Английский

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The Silent Syndrome of Long COVID and Gaps in Scientific Knowledge: A Narrative Review

Viruses, Journal Year: 2024, Volume and Issue: 16(8), P. 1256 - 1256

Published: Aug. 5, 2024

COVID-19 is still a major public health concern, mainly due to the persistence of symptoms or appearance new symptoms. To date, more than 200 long COVID (LC) have been described. The present review describes and maps its relevant clinical characteristics, pathophysiology, epidemiology, genetic nongenetic risk factors. Given currently available evidence on LC, we demonstrate that there are gaps controversies in diagnosis, detection prognostic predictive factors, as well role viral strain vaccination.

Language: Английский

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Effect of long COVID-19 syndrome on health-related quality of life: a cross-sectional study

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: May 30, 2024

Purpose This study aimed to assess the association of anxiety, headache, and insomnia on QoL patients with long COVID-19. Methods We conducted a cross-sectional survey between August 2020 March 2023. A total 200 participants were eligible, 53 excluded 147 COVID included. was evaluated across eight domains using 36-Item Short Form Health Survey (SF-36). Standardized protocols including Beck Anxiety Inventory (BAI) ( n = 103), Pittsburgh Sleep Quality Index (PSQI) 73), Migraine Disability Assessment (MIDAS) 67) also used. Results Participants sleep disorders had significantly lower Vitality p < 0.001). anxiety 0.001), poorer Mental 0.008), more severe Bodily Pain 0.008). headache 0.032), 0.036), Physical Functioning 0.016). both 0.005) 0.043) domain scores. Correlation analysis revealed that higher scores for disorder, independently correlated various domains. The presence disorder associated fourfold increase in risk experiencing diminished (odds ratio [OR]4.47; 95% CI 1.01–19.69; 0.048). Conclusion sleep, tended have worse QoL. most adversely affected COVID. poor Vitality.

Language: Английский

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The Association of Physical Distancing Behaviors to Avoid COVID-19 with Health-Related Quality of Life in Immunocompromised and Non-Immunocompromised Individuals: The Patient-Informed Protocol for the Observational, Cross-Sectional EAGLE Study (Preprint)

JMIR Research Protocols, Journal Year: 2024, Volume and Issue: 13, P. e52643 - e52643

Published: Aug. 13, 2024

Background Immunocompromised individuals are known to respond inadequately SARS-CoV-2 vaccines, placing them at high risk of severe or fatal COVID-19. Thus, immunocompromised and their caregivers may still practice varying degrees social physical distancing avoid However, the association between COVID-19 quality life has not been comprehensively evaluated in any study. Objective We aim measure behaviors among those person-centric outcomes, including health-related (HRQoL) measures, health state utilities, anxiety depression, work school productivity impairment. Methods A patient-informed protocol was developed conduct EAGLE Study, a large cross-sectional, observational study, this paper describes that protocol. is designed outcomes individuals, children (aged ≥6 mo) caregivers, nonimmunocompromised adults United States Kingdom who report no receipt passive immunization against previously novel self- observer-reported instrument, Physical Distancing Scale for Avoidance (PDS-C19), behavior levels cross-sectionally retrospectively. Using an interim randomly selected subset study population, PDS-C19 psychometric properties will be assessed, structural validity, internal consistency, known-group convergent validity. Associations (correlations) assessed validated HRQoL-related measures utilities. Structural equation modeling regression used assess these associations, adjusting potential confounders. Participant recruitment data collection took place from December 2022 June 2023 using direct-to-patient channels, panels, clinician referral, patient advocacy groups, media, with immunocompromising diagnosis confirmation collected 25% participants. The planned total sample size 3718 participants participant-caregiver pairs. Results reported by status, condition category, country, age group, other subgroups. All analyses reporting were completed 2023. submitted publication peer-reviewed journals 2024-2025. Conclusions This quantify individuals’ HRQoL as well International Registered Report Identifier (IRRID) RR1-10.2196/52643

Language: Английский

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Advance in the mechanism and clinical research of myalgia in long COVID

American journal of clinical and experimental immunology., Journal Year: 2024, Volume and Issue: 13(4), P. 142 - 164

Published: Jan. 1, 2024

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve, mortality rates of disease 2019 (COVID-19) have significantly decreased. However, a variable proportion patients exhibit persistent prolonged symptoms COVID-19 infection (long COVID). This virus primarily attacks system, but numerous individuals complain skeletal muscle pain or worsening pre-existing post COVID-19, which severely affects the quality life and recovery. Currently, there is limited research on in long COVID. In this brief review, we review potential pathological mechanisms COVID, summarize various auxiliary examinations treatments for We consider abnormal activation inflammatory response, myopathy, neurological damages as pivotal A comprehensive examination important order work out effective treatment plans relieve pain. So far, rehabilitation interventions myalgia COVID contain are not drug, nutraceutical therapy, gut microbiome-targeted interventional therapy strength training. Our study provides mechanism reference clinical researches, highlighting importance approach management The relief will accelerate process, improve activities daily living enhance life, promoting return society with profound significance.

Language: Английский

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