The association between Planetary Health Diet Index (PHDI) and chronic obstructive pulmonary disease (COPD): the mediating role of dietary inflammatory index (DII)

BMC Pulmonary Medicine, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 31, 2025

Given global changes in the environment and dietary habits, it is critical to understand potential impact of factors inflammation on respiratory diseases, including COPD. Studying these relationships can help develop more effective prevention strategies. PHDI a scoring system designed balance human health environmental sustainability by promoting increased consumption plant-based foods reduced intake red meat, sugar, highly processed foods. In contrast, DII quantifies inflammatory diet. This study examines association between COPD assesses whether mediates this relationship. We used subgroup analysis, smooth curve fitting, multivariable logistic regression investigate connection occurrence Furthermore, mediation analysis was carried out any possible correlation link 30,304 participants were included investigation, 1,498 them reported events. For every 10-point increase each unit associated with 9% reduction (OR = 0.91, 95% CI: 0.86, 0.97) an 8% 1.08, 1.02, 1.13) prevalence COPD, respectively, when all variables adjusted for using regression. Additionally, results remain robust are converted tertile. An investigation fitting showed linear risk PHDI. The that 17.95% relationship mediated (p 0.034). Higher levels lower appears mediate relationship, suggesting anti-inflammatory diet may provide benefits.

Language: Английский

Association of the dietary index for gut microbiota with sleep disorder among US adults: the mediation effect of dietary inflammation index

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: March 17, 2025

Previous studies have confirmed the relationship between gut microbiota and sleep disorders, characterized by persistent inability to achieve adequate sleep, with dietary composition playing a key role in maintaining homeostasis. Our study aims explore newly proposed Dietary Index for Gut Microbiota (DI-GM) as well whether Inflammatory (DII) mediates this relationship. This is based on data from 30,406 participants National Health Nutrition Examination Survey (NHANES) 2005 2018, cross-sectional survey that represents U.S. adult population. We used multivariable logistic regression models examine DI-GM disorders. Subgroup interaction analyses were conducted assess stability of results. Mediation analysis was employed effect The score significantly negatively correlated After adjusting covariates, each unit increase associated 5% reduction prevalence disorders (p < 0.001). Additionally, there trend toward decrease increasing (trend p 0.05). Dose-response curve revealed linear higher scores being lower DII positively 0.001) decreased increased (β = -0.37, showed mediated mediation proportion 27.36% results indicate A incidence while Specifically, an may attenuate protective

Language: Английский