Frontiers in Veterinary Science,
Journal Year:
2024,
Volume and Issue:
11
Published: Oct. 31, 2024
Fungal
probiotics
have
the
potential
as
feed
additives,
but
less
has
been
explored
in
ruminant
up
to
date.
This
study
aimed
determine
effect
of
compound
(CPs)
with
Aspergillus
oryzae
1,
2
and
Candida
utilis
on
Hu
sheep’s
growth
performance,
rumen
fermentation
microbiota.
A
total
120
male
sheep,
aged
months
body
weight
16.95
±
0.65
kg
were
divided
into
4
groups.
Each
group
consisted
5
replicates,
6
sheep
per
replicate.
Group
was
control
fed
basal
diet.
B,
C
D
supplemented
diet
by
adding
400,
800
1,200
grams
ton
(g/t)
CPs,
respectively.
The
feeding
trial
lasted
for
60
days
after
a
10-day
adaptation
period.
results
showed
that
average
daily
gain
(ADG)
CPs
groups
significantly
higher,
feed/gain
lower
than
those
later
stage
overall
addition
increased
economic
benefit.
levels
CD4
+
/CD8
ratio
higher
A.
GSH,
IgG,
IL-2,
IL-6,
IFN-
γ
elevated
compared
B
significant
increase
NH
3
-N
cellulase
activity.
There
no
difference
VFAs
content
between
however,
increasing
butyric
acid
isobutyric
tended
decrease.
microbiota
analysis
indicated
Firmicutes
Proteobacteria
abundances,
decreased
Bacteroidetes
abundance.
correlation
Prevotella
negatively
correlated
ADG,
400
reduced
’s
relative
abundance,
indicating
decreasing
caspase-3,
NF-κB
TNF-
α
expression
liver,
jejunum
tissues.
In
conclusion,
production
inflammation,
improved
intestinal
health.
Considering
above
points
benefits,
optimal
an
additive
is
g/t.
Microorganisms,
Journal Year:
2025,
Volume and Issue:
13(2), P. 217 - 217
Published: Jan. 21, 2025
In
vitro
experiments
were
conducted
to
characterize
the
effect
of
bile
salt
supplementation
and
pH
on
proliferation
Bacillus
subtilis
CE330
Enterococcus
durans
CH33
probiotics
in
vivo
production
performance,
cecal
Salmonella
enterica
serovar
Enteritidis
(S.
Enteritidis)
load,
immune
response
broilers.
A
one-way
ANOVA
was
used
examine
probiotic
species
proliferation.
B.
subtilis.
more
tolerant
high
concentrations
levels
compared
E.
CH33.
Bile
between
3.0
4.0%
a
range
2
4
decreased
(p
<
0.05)
vitro,
cell-free
supernatants
(CFSs)
at
ratio
1:1
significantly
reduced
S.
proliferation,
with
highest
inhibition
observed
5:1
CFS.
The
cultures
4%
for
72
h
had
higher
proline
concentration
56.95
(13.1-fold)
20.09
(2.5-fold)
µmol/g
fresh
weight,
respectively.
total
144
one-day-old
male
Cobb
broiler
chicks
randomly
allocated
four
treatment
groups—basal
diet,
basal
diet
+
challenge,
(B.
CH33,
0.5
g/kg
feed),
challenge
six
replications.
On
day
14,
birds
orally
challenged
1
×
108
CFU
Enteritidis.
two-way
effects
dependent
variables
after
10
d
post-Salmonella
infection.
Probiotic
did
not
alter
body
weight
gain,
feed
conversion
ratio,
intestinal
histomorphology
>
0.05),
or
IL-1β
IL-10
gene
expression
dpi.
However,
load
by
38%
control
group.
conclusion,
38%,
thereby
demonstrating
their
potential
as
interventions
enhance
food
safety
serve
alternatives
antibiotics
poultry.
Hence,
when
developing
multi-strain
formulations,
it
is
essential
emphasize
biocompatibility
various
strains
within
host
system.
Foodborne Pathogens and Disease,
Journal Year:
2022,
Volume and Issue:
19(10), P. 693 - 703
Published: July 29, 2022
The
Campylobacter
genus
is
the
leading
cause
of
human
gastroenteritis,
with
consumption
contaminated
poultry
meat
as
main
route
infection.
Probiotic
bacteria,
such
Lactobacillus,
Bacillus,
Escherichia
coli
Nissle,
and
Bifidobacterium
species,
have
a
great
immunomodulatory
capacity
exhibit
antipathogenic
effects
through
various
molecular
mechanisms.
Reducing
levels
in
livestock
animals,
poultry,
will
substantial
benefit
to
humans
it
reduce
disease
transmissibility
food
chain.
Moreover,
probiotic-based
strategies
might
attenuate
intestinal
inflammatory
processes,
which
consequently
severity
progression.
At
level,
probiotics
can
also
negatively
impact
on
functionality
virulence
survival
factors
(e.g.,
adhesion,
invasion),
associated
colonization
proteins
involved
epithelial
translocation.
current
review
describes
recent
vitro,
vivo,
preclinical
findings
probiotic
therapies,
aiming
counts
pathogen's
avian
host.
we
focused
particular
known
anti-Campylobacter
activity
seeking
understand
biological
mechanisms
their
mode
action.
Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: July 13, 2023
Species
diversification
from
major
to
minor
carps
for
their
sturdiness
and
initial
higher
growth,
also
a
quest
antibiotic-free
aqua
farming
in
the
subcontinent,
mandates
search
evaluation
of
alternatives.
An
experiment
was
performed
investigate
potential
fructooligosaccharide
(FOS)
Bacillus
subtilis
(BS)
(alone
or
as
synbiotics)
promoting
growth
immunity
against
infections
Labeo
fimbriatus
fingerlings.
Six
iso-nitrogenous
iso-lipidic
diets
containing
combinations
two
levels
FOS
(0%
0.5%)
three
BS
(0,
104,
106
CFU/g
feed)
were
fed
fish
60
days.
At
end
feeding
trial,
twenty-four
each
group
injected
intra-peritoneally
with
pathogenic
strain
Aeromonas
hydrophila
O:18
test
immunoprotective
efficacy
supplements
bacterial
infection.
BS,
but
not
FOS,
significantly
improved
(P
<
0.05)
feed
utilisation
attributes
like
percentage
weight
gain
(PWG),
specific
rate
(SGR)
conversion
ratio
(FCR).
There
interactive
effects
on
PWG,
SGR
FCR;
however,
additive
nature.
These
beneficial
alone
combination
corroborated
by
increased
protease
activity,
microvilli
density
diameter
number
goblet
cells.
Overall
included
erythrocyte
(RBC),
hemoglobin
(Hb),
total
protein
globulin
levels.
Total
leucocyte
(WBC)
count
immunological
parameters
respiratory
burst
activity
leucocytes
(NBT
reduction),
lysozyme
albumin:
post-challenge
survival
both
dietary
yielded
highest
improvement
these
parameters.
Synergistic
indicate
that
0.5%
is
optimal
improve
utilisation,
immune
functions,
disease
resistance
L.
Frontiers in Veterinary Science,
Journal Year:
2024,
Volume and Issue:
11
Published: March 1, 2024
Microorganisms
inhabit
the
gastrointestinal
tract
of
ruminants
and
regulate
body
metabolism
by
maintaining
intestinal
health.
The
state
health
is
influenced
not
only
macro-level
factors
optimal
development
physiological
structure
integrity
but
also
delicate
equilibrium
between
flora
immune
status
at
micro-level.
Abrupt
weaning
in
young
causes
incomplete
resulting
an
unstable
unformed
microbiota.
induced
damages
to
microecological
homeostasis
tract,
infections
diseases,
such
as
diarrhea.
Recently,
nutritional
functional
yeast
culture
has
been
researched
tackle
these
problems.
Herein,
we
summarized
current
known
interactions
microorganisms
ruminants,
then
discussed
regulatory
effects
using
a
feed
supplement.
Yeast
preparation
that
contains
yeast,
enriched
with
metabolites
other
nutrient-active
components,
including
β-glucan,
mannan,
digestive
enzymes,
amino
acids,
minerals,
vitamins,
some
unknown
growth
factors.
It
stimulates
proliferation
mucosal
epithelial
cells
reproduction
providing
special
nutrient
substrates
support
function.
Additionally,
β-glucan
mannan
effectively
stimulate
immunity,
promote
response,
activate
macrophages,
increase
acid
phosphatase
levels,
thereby
improving
body’s
resistance
several
disease.
incorporation
into
ruminants’
diet
significantly
alleviated
damage
caused
stress
which
acts
effective
strategy
balance
flora,
tissue,
establishment
system.
Our
review
provides
theoretical
basis
for
application
ruminants.
Microorganisms,
Journal Year:
2022,
Volume and Issue:
10(9), P. 1700 - 1700
Published: Aug. 24, 2022
Probiotics
and
related
preparations,
including
synbiotics
postbiotics,
are
living
non-living
microbial-based
multi-components,
which
now
among
the
most
popular
bioactive
agents.
Such
interests
mainly
arise
from
wide
range
numerous
beneficial
effects
of
their
use
for
various
hosts.
The
current
minireview
article
attempts
to
provide
an
overview
discuss
in
a
holistic
way
concepts,
methodologies,
action
mechanisms,
applications
probiotic-based
multi-components
human,
animal,
plant,
soil,
environment
health.
Probiotic-based
multi-component
preparations
refer
mixture
agents,
containing
probiotics
or
postbiotics
as
main
functional
ingredients,
prebiotics,
protectants,
stabilizers,
encapsulating
other
compounds
additional
constituents.
Analyzing,
characterizing,
monitoring
over
time
traceability,
performance,
stability
such
ingredients
require
relevant
sensitive
analytical
tools
methodologies.
Two
innovative
profiling
methods,
thermophysical
fingerprinting
thermogravimetry–differential
scanning
calorimetry
technique
(TGA-DSC)
whole
powder
Advanced
Testing
Genetic
Composition
(ATGC)
strain
analysis
up
subspecies
level,
presented,
illustrated,
discussed
this
review
respond
those
requirements.
Finally,
paper
deals
with
some
selected
soil
health,
while
mentioning
possible
mechanisms.
STUDIES IN HEALTH SCIENCES,
Journal Year:
2025,
Volume and Issue:
6(1), P. e14243 - e14243
Published: Feb. 19, 2025
A
microbiota
intestinal
desempenha
papel
crucial
na
saúde
de
animais,
contribuindo
para
a
digestão,
imunidade
e
proteção
contra
patógenos.
Fatores
como
dieta
uso
antibióticos
podem
alterar
sua
composição,
levando
à
disbiose
problemas
doenças
inflamatórias.
Este
estudo
avalia
microrganismos
com
apelo
probiótico
em
produtos
comerciais
cães,
analisando
quantidade
no
produto,
resistência
ao
suco
gástrico
suscetibilidade
antifúngicos.
Os
testes
foram
conduzidos
duas
amostras
probióticos
adquiridas
Formiga,
MG,
analisadas
Laboratório
Microbiologia
do
UNIFOR-MG.
metodologia
incluiu
simulação
pH
(pH
3,0)
sensibilidade
antifúngicos
(miconazol,
cetoconazol
clotrimazol).
cultivados
expostos
condições
controladas
medir
sobrevivência
funcionalidade.
resultados
indicaram
que
apenas
uma
amostra,
amostra
A,
apresentou
viabilidade
satisfatória,
alcançando
10⁶
UFC/g
após
gástrica.
Isso
demonstra
o
é
resistente
ácido
provavelmente
mantém
funcionalidade
trato
gastrointestinal.
Adicionalmente,
análise
aos
revelou
as
leveduras
da
sensíveis
às
drogas
testadas,
destacando
segurança
veterinário.
Conclui-se
Saccharomyces
cerevisiae
pode
ser
eficaz
equilíbrio
auxiliando
disbioses
intestinais.
