Journal of the Indian Chemical Society, Journal Year: 2024, Volume and Issue: unknown, P. 101454 - 101454
Published: Oct. 1, 2024
Language: Английский
International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(3), P. 1032 - 1032
Published: Jan. 25, 2025
The use of medicinal plants represents an alternative method for bacterial control due to their chemical compositions. This study’s objective was determine the inhibitory capacity Larrea tridentata extracts against microbial strains clinical interest. Four were prepared, phytochemical profiles determined, and antioxidant capacities quantified. Additionally, minimum concentrations hemolysis determined using human blood erythrocytes. For extracts’ growth capacity, six two fungal evaluated disk diffusion test. Commercial medications specific each strain used as controls. ethanolic registered greatest diversity metabolites related antibacterial activity. activities extract Cedax® similar Enterococcus faecalis. A principal component analysis performed with X2 ANOVA tests identify relationships effects on inhibition, obtaining p > 0.05 a confidence level 95%. research highlights potential L. treatment mitigate growing problem resistance traditional antibiotics.
Language: Английский
Citations
1
Results in Chemistry, Journal Year: 2024, Volume and Issue: unknown, P. 101864 - 101864
Published: Oct. 1, 2024
Language: Английский
Citations
4
Antibiotics, Journal Year: 2025, Volume and Issue: 14(1), P. 54 - 54
Published: Jan. 9, 2025
Background/Objectives: The prolonged use of antibiotics is closely related to increased infections caused by Clostridioides difficile (Cdiff). Plant-origin compounds have been expanding in recent years as the best opportunity identify new synergic therapies combat antibiotic-associated diseases. Mexico has incredible plant biodiversity; natural with antibacterial properties are an alternative treatment. main objective this study was analyze effect medicinal plants action against toxigenic clinical Cdiff strains that a on commonly used disease. Methods: were selected for previously research, and their extracts tested strains. activity, synergy, antagonism between evaluated. Results: Our results demonstrated some effective antimicrobial activity effects vancomycin metronidazole. Conclusions: This suggests derived from these could be synergic-antibiotic therapy infections.
Language: Английский
Citations
0
The Scientific World JOURNAL, Journal Year: 2025, Volume and Issue: 2025(1)
Published: Jan. 1, 2025
The present study was aimed to verify the medicinal value of Croton macrostachyus and Pycnostachys abyssinica traditionally used treat human animal ailments in Ethiopia. Fresh leaves these species were collected, dried under shade, ground into fine powder. extraction carried out by maceration method using methanol as a solvent. compounds crude extract further profiled thin layer chromatography (TLC). antibacterial activity evaluated agar well diffusion method. C . had higher percentage yield (22.5%) than P (13.7%). phytochemical screening showed more abundant phenolic tannins alkaloid, flavonoid, compounds, Overall, produced twofold growth inhibition zone (24.0 ± 0.5–43.0 1.0 mm) against tested pathogens (7.0 0.5–24.0 0.3 mm). Among bacteria, Klebsiella pneumoniae found be most sensitive lowest minimum inhibitory concentration (MIC) values (25 mg/mL) obtained from 1 3 leaf Escherichia coli K 2 same S aureus Similarly, compound MIC Staphylococcus epidermidis E All two both bactericidal bacteriostatic properties pathogens. results revealed that strong all pathogens, indicating high potential compounds. However, characterization identification specific for development biocide formulations are suggested.
Language: Английский
Citations
0
eFood, Journal Year: 2025, Volume and Issue: 6(1)
Published: Jan. 20, 2025
ABSTRACT Mushrooms have long been an integral part of human culture and health are valued for their nutritional therapeutic properties. Often referred to as a superfood, mushrooms rich in bioactive compounds that provide range benefits including antioxidant, antimicrobial, anticancer, prebiotic, antidiabetic, anti‐inflammatory effects. This review focussed on the diversity mushrooms, emphasizing medicinal significance, explores secondary metabolites with potential applications nutraceuticals pharmaceuticals. It underscores role vital agents developing value‐added products. An overview compounds, such polysaccharides, peptides, proteins, terpenoids, phenolic identified numerous mushroom species. Additionally, addresses advancements fungal biotechnology, particularly use fungi efficient industrial cell factories, influence food quality sustainability. By critically analyzing recent studies, summarizes diverse roles biomolecules pharmaceutical industries highlights significant contribution modern medicine health‐related fields.
Language: Английский
Citations
0
Asian Journal of Research in Biochemistry, Journal Year: 2025, Volume and Issue: 15(1), P. 48 - 62
Published: Jan. 23, 2025
Antimicrobial resistance (AMR) is a grave threat to global health that made worse by the abuse and excessive use of antibiotics. This review looks into processes this bacterial resistance, particularly efflux pump systems, calls for consideration alternative approaches. The antimicrobial plant derived bioactive compounds, rich in phytochemicals, are significance as they can serve mute mechanisms. Some core active compounds such flavonoids, alkaloids, phenolics, essential oils have been proven work on some multi-drug resistant pathogens Among other things, also discusses how phytochemicals interact with ordinary antibiotics improve drug effectiveness while minimizing chances resistance. case studies emphasized suggest antimicrobials potent tools fight against AMR. In conclusion, results emphasize need incorporation within modern treatment approaches order curb problems AMR world.
Language: Английский
Citations
0
Research Journal of Botany, Journal Year: 2025, Volume and Issue: 20(1), P. 83 - 87
Published: Jan. 26, 2025
Language: Английский
Citations
0
Archives of Microbiology, Journal Year: 2025, Volume and Issue: 207(3)
Published: Feb. 14, 2025
Language: Английский
Citations
0
The Microbe, Journal Year: 2025, Volume and Issue: unknown, P. 100281 - 100281
Published: Feb. 1, 2025
Language: Английский
Citations
0
Microorganisms, Journal Year: 2025, Volume and Issue: 13(3), P. 611 - 611
Published: March 6, 2025
Phyllanthus emblica Linn. (commonly known as Amla or Indian Gooseberry) is commonly used in Ayurvedic medicine to treat respiratory infections, skin disorders, and gastrointestinal issues. The fruit contains an abundance of polyphenols, which contribute its strong antioxidant properties. antibacterial activity extracts derived from P. against Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae was determined along with the antibiotic-resistant variants extended-spectrum β-lactamase (ESBL) E. methicillin-resistant S. aureus (MRSA), ESBL K. pneumoniae. Disc diffusion broth dilution assays were conducted assess aqueous, methanolic, ethyl acetate extracts, large zones inhibition up 15 mm on agar observed for MRSA. Minimum inhibitory concentration (MIC) values ranging 158 1725 µg/mL calculated. aqueous methanolic less active pneumoniae, only noteworthy MIC (633 µg/mL) extract Interestingly, a lack any these bacteria. Liquid chromatography–mass spectrometry (LC-MS) analysis identified several notable flavonoids, phenolic acids, terpenoids, tannins. Notably, Artemia nauplii bioassays indicated that all nontoxic. absence toxicity suggest their potential candidates antibiotic development, highlighting need further mechanistic phytochemical investigations.
Language: Английский
Citations
0