Frontiers in Antibiotics,
Journal Year:
2024,
Volume and Issue:
2
Published: Jan. 26, 2024
Multidrug-resistant
organisms
are
bacteria
that
no
longer
controlled
or
killed
by
specific
drugs.
One
of
two
methods
causes
multidrug
resistance
(MDR);
first,
these
may
disguise
multiple
cell
genes
coding
for
drug
to
a
single
treatment
on
(R)
plasmids.
Second,
increased
expression
efflux
pumps,
which
extrude
many
drugs,
can
cause
MDR.
Antibiotic
is
big
issue
since
some
withstand
almost
all
antibiotics.
These
serious
sickness,
making
them
public
health
threat.
Methicillin-resistant
Staphylococcus
aureus
(MRSA),
vancomycin-resistant
Enterococcus
(VRE),
Multidrug
resistant
Mycobacterium
tuberculosis
(TB),
and
CRE
gut
resist
Antimicrobial
rising
worldwide,
increasing
clinical
community
morbidity
mortality.
Superbugs
have
made
antibiotic
in
environmental
niches
even
harder
control.
This
study
introduces
new
medicinal
plants,
gene-editing
methods,
nanomaterials,
bacterial
vaccines
will
fight
MDR
the
future.
Antibiotics,
Journal Year:
2020,
Volume and Issue:
9(2), P. 45 - 45
Published: Jan. 26, 2020
The
prevalence
of
fungal
infections
is
growing
at
an
alarming
pace
and
the
pathogenesis
still
not
clearly
understood.
Recurrence
these
diseases
often
due
to
their
evolutionary
avoidance
antifungal
resistance.
development
suitable
novel
antimicrobial
agents
for
continues
be
a
major
problem
in
current
clinical
field.
Hence,
it
urgently
necessary
develop
surrogate
that
are
more
effective
than
conventional
available
drugs.
Among
remarkable
innovations
from
earlier
investigations
on
natural-drugs,
flavonoids
group
plant-derived
substances
capable
promoting
many
valuable
effects
humans.
identification
with
possible
small
concentrations
or
synergistic
combinations
could
help
overcome
this
problem.
A
combination
drugs
excellent
approach
reduce
side
toxicity.
This
review
focuses
various
naturally
occurring
activities,
modes
action,
synergetic
use
Foods,
Journal Year:
2021,
Volume and Issue:
10(4), P. 752 - 752
Published: April 1, 2021
(L.)
belongs
to
the
Myrtaceae
family
and
it
is
an
important
fruit
in
tropical
areas
like
India,
Indonesia,
Pakistan,
Bangladesh,
South
America.
The
leaves
of
guava
plant
have
been
studied
for
their
health
benefits
which
are
attributed
plethora
phytochemicals,
such
as
quercetin,
avicularin,
apigenin,
guaijaverin,
kaempferol,
hyperin,
myricetin,
gallic
acid,
catechin,
epicatechin,
chlorogenic
epigallocatechin
gallate,
caffeic
acid.
Extracts
from
(GLs)
biological
activities,
including
anticancer,
antidiabetic,
antioxidant,
antidiarrheal,
antimicrobial,
lipid-lowering,
hepatoprotection
activities.
In
present
review,
we
comprehensively
nutritional
profile
phytochemical
GLs.
Further,
various
bioactivities
GL
extracts
also
discussed
critically.
Considering
beneficial
effects
GLs,
they
can
potentially
be
used
ingredient
development
functional
foods
pharmaceuticals.
More
detailed
clinical
trials
need
conducted
establish
efficacy
extracts.
Frontiers in Sustainable Food Systems,
Journal Year:
2021,
Volume and Issue:
5
Published: Feb. 18, 2021
There
is
increasing
interest
in
the
use
of
natural
preservatives
(rather
than
synthetic
ones)
for
maintaining
quality
and
safety
foods
due
to
their
perceived
environmental
health
benefits.
In
particular,
plant-based
antimicrobials
are
being
employed
protect
against
microbial
spoilage,
thereby
improving
food
safety,
quality,
shelf-life.
However,
many
cannot
be
utilized
free
form
chemical
instability,
poor
dispersibility
matrices,
or
unacceptable
flavor
profiles.
For
these
reasons,
encapsulation
technologies,
such
as
nanoemulsions,
developed
overcome
hurdles.
Indeed,
can
improve
handling
ease
use,
well
enhance
potency.
This
review
highlights
various
kinds
that
available
applications.
It
then
describes
methods
forming
nanoemulsions
shows
how
they
used
encapsulate
deliver
preservatives.
Finally,
potential
applications
nano-emulsified
demonstrated
meat,
fish,
dairy,
fresh
produce
areas.
International Journal of Microbiology,
Journal Year:
2022,
Volume and Issue:
2022, P. 1 - 7
Published: March 23, 2022
Edible
mushrooms
are
fungi
that
can
be
seen
with
the
naked
eye
and
relatively
easy
to
gather
by
hand.
This
review
article
highlights
health
benefit
biochemistry
of
several
mushroom
species.
AIMS Microbiology,
Journal Year:
2019,
Volume and Issue:
5(2), P. 117 - 137
Published: Jan. 1, 2019
The
increasing
emergence
of
multidrug-resistant
infection
causing
microorganisms
has
become
a
significant
burden
globally.
Despite
the
efforts
pharmaceuticals
in
producing
relatively
new
antimicrobial
drugs,
they
have
resulted
high
rate
mortality,
disability
and
diseases
across
world
especially
developing
countries.
Supporting
this
claim
was
report
Centre
for
Disease
Control
Prevention
(CDC)
who
estimated
that
over
2
million
illnesses
23,000
deaths
per
year
are
attributable
to
antibiotic
resistant
pathogens
United
States.
They
include
Methicillin-resistant
Czech Journal of Food Sciences,
Journal Year:
2021,
Volume and Issue:
39(2), P. 71 - 94
Published: April 29, 2021
Dragon
fruit:
A
review
of
health
benefits
and
nutrients
its
sustainable
development
under
climate
changes
in
Vietnam
|
Thi-Thuy-Hai
Luu,
Truc-Linh
Le,
Nga
Huynh,
Pablo
Quintela-Alonso
Agricultural
Journals
Horticulturae,
Journal Year:
2022,
Volume and Issue:
8(5), P. 401 - 401
Published: May 3, 2022
Plants
are
a
reservoir
of
phytochemicals,
which
known
to
possess
several
beneficial
health
properties.
Along
with
all
the
secondary
metabolites,
polyphenols
have
emerged
as
potential
replacements
for
synthetic
additives
due
their
lower
toxicity
and
fewer
side
effects.
However,
controlling
microbial
growth
using
these
preservatives
requires
very
high
doses
plant-derived
compounds,
limits
use
only
specific
conditions.
Their
at
concentrations
leads
unavoidable
changes
in
organoleptic
properties
foods.
Therefore,
biochemical
modification
natural
can
be
promising
alternative
enhance
antimicrobial
efficacy
compounds/polyphenols.
Amongst
modifications,
low
concentration
ascorbic
acid
(AA)–Cu
(II),
degradation
products
(DPAA),
Maillard
reaction
(MRPs),
laccase–mediator
(Lac–Med)
horse
radish
peroxidase
(HRP)–H2O2
systems
standout.
This
review
reveals
importance
plant
polyphenols,
role
agents,
mechanism
methods
ways
may
used
enhancing
potency
polyphenols.
Ultimately,
this
study
act
base
development
potent
agents
that
find
food
applications.
Molecules,
Journal Year:
2023,
Volume and Issue:
28(3), P. 1068 - 1068
Published: Jan. 20, 2023
Natural
extracts
have
been
and
continue
to
be
used
treat
a
wide
range
of
medical
conditions,
from
infectious
diseases
cancer,
based
on
their
convenience
therapeutic
potential.
products
derived
microbes,
plants,
animals
offer
broad
variety
molecules
chemical
compounds.
are
not
only
one
the
most
important
sources
for
innovative
drug
development
animal
human
health,
but
they
also
an
inspiration
synthetic
biology
chemistry
scientists
towards
discovery
new
bioactive
compounds
pharmaceuticals.
This
is
particularly
relevant
in
current
context,
where
antimicrobial
resistance
has
risen
as
global
health
problem.
Thus,
efforts
being
directed
toward
studying
natural
compounds’
composition
potential
generate
drugs
with
better
efficacy
lower
toxicity
than
existing
molecules.
Currently,
methodologies
analyze
vitro
activity
determine
suitability
agents.
Despite
traditional
technologies
employed,
technological
advances
contributed
implementation
methods
able
circumvent
issues
related
analysis
capacity,
time,
sensitivity,
reproducibility.
review
produces
updated
conventional
evaluate
