Advancements in Nanocarrier-Mediated Drug Delivery: Precision Strategies for Targeted Therapeutics and Improved Treatment Outcomes

Interdisciplinary cancer research, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

---

Enhanced Skin Penetration of Ascorbyl Palmitate Achieved via Liposomal Encapsulation: Tape Stripping Evaluation

Published: June 13, 2024

L-ascorbic acid represents one of the most potent antioxidant, photoprotective, anti-aging and anti-pigmentary cosmeceutical agents, with a good safety profile. However, challenge remained to design stable topical formulation, such permeability as active that optimal effects on skin could be achieved. The aim our research was evaluate difference between penetration ability ascorbyl palmitate incorporated in same percentage (2%) within creams emulgels carriers, well determine impact its incorporation into liposome kinetics penetration. Tape stripping applied for studying stratum corneum. In addition, sensory textural properties examined formulations were determined. both cases (liposomal non-liposomal formulations), exhibited better profile substance compared use emulgel. Encapsulation liposomes led an increase adhesiveness density prepared cream emulgel samples. best spreadability absorption during application detected liposomal obtained results confirmed improved dermal palmitate, either or bases employed, which further indicates advantages encapsulation.

Language: Английский

---

Liposomal Encapsulation of Ascorbyl Palmitate: Influence on Skin Performance

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(7), P. 962 - 962

Published: July 20, 2024

L-ascorbic acid represents one of the most potent antioxidant, photoprotective, anti-aging, and anti-pigmentation cosmeceutical agents, with a good safety profile. However, main challenge is formulation stable topical products, which would optimize penetrability through skin. The aim our research was to evaluate performance ascorbyl palmitate on skin, incorporated in creams emulgels (2%) as carriers, well determine impact its incorporation into liposomes penetration profile this ingredient. Tape stripping used study stratum corneum. In addition, sensory textural properties formulations were determined. liposomal exhibited better (p < 0.05) active substance compared non-liposomal counterpart, leading 1.3-fold 1.2 fold-increase total amount penetrated corneum for emulgel cream, respectively. Encapsulation led an increase adhesiveness density prepared cream samples. best spreadability absorption during application detected obtained results confirmed that encapsulation improved dermal both formulations.

Language: Английский

---

Recent advances in the application of next-generation chitosan-based nanoparticles applied in the management of numerous kidney diseases and its complications

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 543 - 560

Published: Nov. 8, 2024

Language: Английский

---

The commercial importance to develop validated analytical methods to define phytochemical levels in herbal medicinal products

Phytotherapy Research, Journal Year: 2022, Volume and Issue: 36(10), P. 3675 - 3677

Published: May 10, 2022

Language: Английский

---