Novel Antioxidants Based on Selected 3d Metal Coordination Compounds with 2-Hydroxybenzaldehyde 4,S-Diallylisothiosemicarbazone DOI Creative Commons
Vasilii Graur, Anastasia Mardari, П. Боурош

et al.

Acta chimica slovenica, Journal Year: 2023, Volume and Issue: 70(1), P. 122 - 130

Published: March 11, 2023

2-Hydroxybenzaldehyde 4,S-diallylisothiosemicarbazone (HL) was synthesized and characterized by 1H, 13C NMR FTIR spectroscopies. It exists in solution two isomeric forms: cis (~25%) trans (~75%). Six stable complexes were obtained interaction of HL with copper(II), nickel(II), cobalt(III) iron(III) salts: [Cu(L)Cl] (1), [Cu(L)NO3] (2), [Cu(3,4-Lut)(L)NO3] (3), [Ni(L)OAc] (4), [Co(L)2]Cl (5), [Fe(L)2]NO3 (6). The have been studied elemental analysis, FTIR, molar electrical conductivity single crystal X-ray diffraction For all compounds the antioxidant activity against cation radicals ABTS•+ studied. All free ligand are more active than trolox that is used medicine practice. Complex 4 (IC50=7.20µM) most one. introduction heterocyclic amine did not improve activity. S-allyl group into isothiosemicarbazone affected substances, some cases resulting exhibit greater isothiosemicarbazones other S-radicals.

Language: Английский

Diet-Derived Antioxidants: The Special Case of Ergothioneine DOI Creative Commons
Barry Halliwell, Richard M.Y. Tang, Irwin K. Cheah

et al.

Annual Review of Food Science and Technology, Journal Year: 2023, Volume and Issue: 14(1), P. 323 - 345

Published: Jan. 10, 2023

This article reviews what is presently known about the biological roles of diet-derived compound ergothioneine (ET). ET seems important to humans because it rapidly taken up from diet by a transporter largely or completely specific for ET, and once retained within body weeks months. The various possible functions in vivo are explored. Much emphasis has been placed on antioxidant properties but although these well established vitro, evidence that activity principal function weak. not unique this: vitamin C polyphenols such as flavonoids also By contrast, α-tocopherol demonstrated effects humans.

Language: Английский

Citations

43

Pickering Emulsion Morphology: Stabilization and Applications of Double Emulsions DOI

C. Joseph,

Omar Bashir, Tawheed Amin

et al.

Food and Humanity, Journal Year: 2025, Volume and Issue: unknown, P. 100525 - 100525

Published: Feb. 1, 2025

Language: Английский

Citations

2

Green Synthesis of Red Fluorescent Graphene Quantum Dots Using Withania somnifera Leaves: Exploring Antidiabetic and Antioxidant Potential DOI Creative Commons
Sudhir Kumar Kataria,

Pooja Kadyan,

J. P. Saini

et al.

International Journal of Biomaterials, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

In recent years, green synthesis methods for producing nanomaterials have gained significant interest due to their environmentally friendly nature and wide‐ranging applications. The present study addresses a novel of graphene quantum dots (GQDs) using leaves Withania somnifera. size, morphology, stability the green‐synthesized GQDs were characterized TEM, UV‐Visible spectroscopy, Fluorescence spectrophotometer, XRD, DLS. bio‐functional properties investigated, with focus on antidiabetic antioxidant capabilities. Their activity was assessed by examining ability inhibit α‐amylase α‐glucosidase enzymes, which play crucial role in glucose metabolism. Additionally, evaluated DPPH● scavenging assays, highlighting effectiveness neutralizing free radicals. findings revealed that synthesized outperformed original leaf extract both enzyme inhibition. exhibited higher IC 50 values inhibiting DPPH (78.508 ± 5.71), (161.909 6.188), (133.345 7.328) compared GQDs, showed lower 72.74 5.9, 137.966 6.95, 122.084 5.478, respectively. indicate somnifera derived hold potential medical applications, warranting further investigation into therapeutic efficacy. This offers comprehensive analysis fundamental biological addressing dual challenges activity.

Language: Английский

Citations

2

The Overlooked Risk of Horizontal Transfer of Plasmid-Borne Antibiotic Resistance Genes Induced by Synthetic Phenolic Antioxidants DOI

Jixiao Xu,

Danna Ding,

Yuhang Fan

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 488, P. 137459 - 137459

Published: Feb. 1, 2025

Language: Английский

Citations

1

Antioxidant Materials in Oral and Maxillofacial Tissue Regeneration: A Narrative Review of the Literature DOI Creative Commons
Niloufar Abedi, Zahra Sadat Sajadi-Javan, Monireh Kouhi

et al.

Antioxidants, Journal Year: 2023, Volume and Issue: 12(3), P. 594 - 594

Published: Feb. 27, 2023

Oral and maxillofacial tissue defects caused by trauma, tumor reactions, congenital anomalies, ischemic diseases, infectious surgical resection, odontogenic cysts present a formidable challenge for reconstruction. Tissue regeneration using functional biomaterials cell therapy strategies has raised great concerns in the treatment of damaged during past few decades. However, implantation transplantation, production excessive reactive oxygen species (ROS) may hinder repair as it commonly causes severe injuries leading to damage. These products exist form oxidant molecules such hydrogen peroxide, superoxide ions, hydroxyl radicals, nitrogen oxide. days, many scientists have focused on application ROS-scavenging components body process. One these scavenging is antioxidants, which are beneficial materials tissues keeping safe against free radicals. Antioxidants divided into natural synthetic sources. In current review article, different antioxidant sources their mechanism action discussed. The applications antioxidants oral tissues, including hard cranial, alveolar bone, dental tissue, soft (dental pulp, periodontal tissue), facial nerve, cartilage also highlighted following parts.

Language: Английский

Citations

18

Antioxidant activity analysis of collagen peptide-magnesium chelate DOI Creative Commons
Chao Zhang,

Bowei Du,

Zihao Song

et al.

Polymer Testing, Journal Year: 2022, Volume and Issue: 117, P. 107822 - 107822

Published: Oct. 7, 2022

Antioxidant peptides from natural polymer collagen are highly desirable and their ability to coordinate with minerals will provide new leads for the prevention treatment of oxidative stress-related diseases. Here, we tested changes structures functional properties bovine bone (BBCP) after magnesium chelation. The Fourier transform infrared (FTIR) results revealed that Mg(II) chelated BBCP mainly via amino nitrogen carboxyl oxygen atoms. fluorescence circular dichroism (CD) indicated could induce stabilize conformational structures, change acid distribution on surfaces BBCP. chelation led improvement radical scavenging activities, enhanced intracellular antioxidant enzyme activities GSH levels, thus demonstrating higher protective reparative effects against H2O2-induced damage. This work provides mechanistic insights further development peptide-magnesium chelates stress mitigation.

Language: Английский

Citations

28

Antibacterial and antioxidant activity of endophytic fungi isolated from Peronema canescens leaves DOI Open Access
Elfita Elfita, Rian Oktiansyah,

MARDIYANTO MARDIYANTO

et al.

Biodiversitas Journal of Biological Diversity, Journal Year: 2022, Volume and Issue: 23(9)

Published: Sept. 20, 2022

Abstract. Elfita, Oktiansyah R, Mardiyanto, Widjajanti H, Setiawan A. 2022. Antibacterial and antioxidant activity of endophytic fungi isolated from Peronema canescens leaves. Biodiversitas 23: 4783-4792. Jack. or sungkai is a plant found in tropical rainforests. Also known as heterophyllum Miq., it belongs to the Verbenaceae family grows widely Thailand, Malaysia, Indonesia. The local people believe that antibacterial properties its leaves increase immunity. Bioactivities associated with medicinal plants are currently great interest due their potential for development use pharmaceutical, agricultural, industrial fields. In this study, we investigated an extract P. host compared them those extracts fungus. compounds derived active have capability be developed source equivalent host. were fresh tissue identified morphologically. Their was tested using Kirby-Bauer method, DPPH method. activities molecularly, column chromatography. A structural determination conducted by spectroscopy involving NMR 1D 2D. Twelve gained leaves, namely RD1-RD12. RD6 isolate showed greatest activity, molecular identification expressed Penicillium oxalicum. pure compound produced yellowish white solid strong activity. Based on analysis 2D, I 3-(2,6-dihydroxyphenyl)-2-hydroxyacrylic acid. study demonstrated functioning agents produce plant. These represent new antibacterials antioxidants.

Language: Английский

Citations

21

Dendrobium officinale flos water extract ameliorates ethanol‐induced acute gastric mucosal injury via inhibiting oxidative stress and inflammation DOI
Pinglong Fan,

Shuchun Xie,

ZhiQian Zhang

et al.

Journal of the Science of Food and Agriculture, Journal Year: 2024, Volume and Issue: 104(14), P. 8593 - 8603

Published: June 26, 2024

Dendrobium officinale flos (DOF), a novel food raw material, is used in Chinese folk medicine to nourish the stomach. However, there still no available study evaluate effects of DOF on animal models acute gastric injury and its mechanism by modern pharmacological research.

Language: Английский

Citations

4

Innovative electrochemical sensor design for carcinogenic antioxidant detection: Bimetallic phosphate nanoparticles decorated on reduced graphene oxide nanosheets DOI

Santhiyagu Sahayaraj Rex Shanlee,

Vinitha Mariyappan, Shen‐Ming Chen

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: 475, P. 143340 - 143340

Published: Feb. 10, 2025

Language: Английский

Citations

0

Synthesis, Characterization, and Molecular Docking Studies of Chalcone-Based Imidazole Derivatives as Potential Antioxidant Agents DOI
Rehab Kamel, Nabeel A. Abdul‐Rida

Russian Journal of General Chemistry, Journal Year: 2025, Volume and Issue: 95(3), P. 715 - 721

Published: March 1, 2025

Language: Английский

Citations

0