Food Hydrocolloids, Journal Year: 2025, Volume and Issue: unknown, P. 111228 - 111228
Published: Feb. 1, 2025
Language: Английский
Journal of Functional Foods, Journal Year: 2022, Volume and Issue: 100, P. 105365 - 105365
Published: Dec. 18, 2022
The human gastrointestinal tract harbors a diverse range of microbial species, which helps to regulate various biological processes such as homeostasis the gut barrier, stimulation immune system, and neurological health benefits from gut-brain axis. Further, microbiome has been found aid in uptake nutrients food large intestines. dietary changes may lead significant population, suggest that positive change can be made diversity by changing style. potential substances positively enhance populations could antioxidants, possess many multiple oxidative stress-related diseases cardiovascular disease, cancer, diabetes, obesity, etc. Food antioxidants are necessary required body balance stress generated biochemical metabolic reactions. interactions between microbiota vital for maintenance microbiome, it bacteria influences bioavailability increasing production bioactive metabolites through microbiome. It is evident different studies food-derived population have an active interaction leading alleviation dysbiosis. A plethora clinical impact on microflora developing microbe-targeting therapeutics diseases. This review discusses major antioxidant groups, with these in-depth pre-clinical interventions.
Language: Английский
Citations
39
Journal of Agriculture and Food Research, Journal Year: 2023, Volume and Issue: 14, P. 100834 - 100834
Published: Oct. 27, 2023
Nutritional deficiency is becoming a universal problem, resulting in poor health, low worker productivity, high rates of mortality and morbidity. Large-scale dietary improvements are needed to deliver healthy, sustainable diet the increasing world population. Fruits vegetables as well their valorized wastes industrial by-products constitute major sources bioactive compounds, including carotenoids. Carotenoids lipophilic pigments that occur widely nature distributed plants, fish, birds, algae, archaea, yeasts, fungi, bacteria, invertebrate animals (such insects, mites, aphids). The most significant aspects carotenoids human antioxidant provitamin A activities, also color they impart our food. researched diets commonly occurring blood β-carotene, β-cryptoxanthin, lycopene, lutein α-carotene, with β-carotene comprising portion pro-vitamin A. Phytoene phytofluene recently increasingly topical diet. Genotype, environment, climate, post-harvest handling processing among factors affecting Thus, this review, results from several studies on recent developments carotenoid sources, marketability, biofortification, new insights for valorization food agro-industrial by-products, health effects concentrations compositions critically pinpointed briefly discussed. Lastly, research needs, mainly crop waste valorization, therapeutic properties highlighted so enhance production nutritional values potentially benefits.
Language: Английский
Citations
38
Heliyon, Journal Year: 2023, Volume and Issue: 9(11), P. e21196 - e21196
Published: Oct. 24, 2023
Designing and manufacturing functional bioactive ingredients pharmaceuticals have grown worldwide. Consumers demand for safe concerns over harmful synthetic additives prompted food manufacturers to seek safer sustainable alternative solutions. In recent years the preference by consumers natural agents compounds increased exponentially, consequently, naturally derived phytochemicals compounds, with antimicrobial antioxidant properties, becoming essential in packaging field. response societal needs, needs be developed based on practices, marketing strategies, consumer behaviour, environmental concerns, emergence of new technologies, particularly bio- nanotechnology. This critical systematic review assessed role from resources behaviour patterns relation phytochemical biologically active substances used development packaging. The use inside materials industry could generate unpleasant odours diffusion most volatile material environment. These must addressed understand minimum concentrations that will not affect sensory aroma negative perceptions. research articles were carefully chosen selected following Preferred Reporting Items Systematic Reviews (PRISMA) guidelines.
Language: Английский
Citations
36
Gels, Journal Year: 2023, Volume and Issue: 9(8), P. 620 - 620
Published: Aug. 1, 2023
Sodium alginate is one of the most interesting and investigated applied biopolymers due to its advantageous properties. Among them, easy, simple, mild, rapid, non-toxic gelation by divalent cations important. In addition, it abundant, low-cost, eco-friendly, bio-compatible, bio-adhesive, biodegradable, stable, etc. All those properties were systematically considered within this review. Carotenoids are functional components in human diet with plenty health benefits. However, their sensitivity environmental process stresses, chemical instability, easy oxidation, low water solubility, bioavailability limit food pharmaceutical applications. Encapsulation may help overcoming these limitations review, role alginate-based encapsulation systems improving stability carotenoids explored. It be concluded that all increase carotenoid stability, but only micro- nano-size, as well emulsion-based, improve bioaccessibility. incorporation other further system Furthermore, main techniques for evaluating briefly considered. This review critically profoundly explains alginates carotenoids, suggesting best alternatives systems. Moreover, provides a comprehensive cover recent advances field.
Language: Английский
Citations
26
Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10
Published: July 26, 2023
Brown seaweeds are excellent sources of bioactive molecules with a wide range pharmacological effects, whose content can vary depending on several factors, including the origin and environment in which algae grow.This study aimed to estimate 19 compounds regarding primary secondary metabolites eight brown macroalgal species from clean Egyptian Red Sea coast. A proximate analysis, pigment, phenolic compounds, vitamin contents were determined. In addition, energy antioxidant activity estimated explore potential application as functional foods encourage species' commercialization.Based chemical composition, Polycladia myrica was most valuable species, comparatively high protein 22.54%, lipid 5.21%, fucoxanthin 3.12 μg/g, β-carotene 0.55 mg/100 g, carbohydrate 45.2%. This also acts great source C, flavonoids, tannins, phenol total capacity.The selected indicated that its phenol, pigment powerful based structure-activity relationships. result verified by strong correlation statistical analysis at 95% confidence level. From worldwide perspective obtained results, these may be reinforced an essential line future foods.
Language: Английский
Citations
24
Molecules, Journal Year: 2024, Volume and Issue: 29(3), P. 728 - 728
Published: Feb. 4, 2024
The elevated occurrence of non-melanoma skin cancer (NMSC) and the adverse effects associated with available treatments adversely impact quality life in multiple dimensions. In connection this, there is a necessity for alternative approaches characterized by increased tolerance lower side effects. Natural compounds could be employed due to their safety profile effectiveness inflammatory neoplastic diseases. These anti-cancer drugs are often derived from natural sources such as marine, zoonotic, botanical origins. should exhibit anti-carcinogenic actions through various pathways, influencing apoptosis potentiation, cell proliferation inhibition, metastasis suppression. This review provides an overview used chemotherapies, chemoprevention, promotion regeneration, including polyphenolic compounds, flavonoids, vitamins, alkaloids, terpenoids, isothiocyanates, cannabinoids, carotenoids, ceramides.
Language: Английский
Citations
17
Journal of Biomolecular Structure and Dynamics, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 21
Published: Jan. 30, 2024
Phytolacca americana L. is of great interest as a traditional additive in various folk remedies several countries, including Turkey. We aimed to determine the chemical profile (assisted by high-Performance liquid chromatography-electrospray ionization-tandem mass apectrometry (HPLC-ESI-MS/MS) experiments three extracts obtained different polarity solvents viz. ethyl acetate (to extract semipolar compounds), methanol and water highly polar metabolites) from P. leaves. Their anti-diabetic effects were investigated vitro assessing their inhibition toα-amylase α-glucosidase. Assessment neuroprotective potential was carried out against acetyl-(AChE) butyryl-(BChE) cholinesterase enzymes. HPLC-ESI-MS/MS showed total 17 chromatographic peaks primarily classified six flavonoids, two saponins, fatty acids. Antioxidant assays revealed remarkable activity for extracts. The BChE considerably more significant (4.08 mg galantamine equivalent (GALAE)/g) extract, whereas had good inhibitory efficacy AChE (2.05 GALAE/g). Through network pharmacology, compounds' mechanism action targeted key gene associated diseases identified. hubb signal transducer activator transcription 3 (STAT3) tumour necrosis factor (TNFα) where compound's site inflammation bowel disease. results offer possibilities prospective application metabolic regulation, blood glucose control, source bioactive compounds with enzyme characteristics which could be relevance cosmetic or pharmaceutical industry combating melanogenesis.
Language: Английский
Citations
14
Journal of Separation Science, Journal Year: 2024, Volume and Issue: 47(1)
Published: Jan. 1, 2024
Like other traditional medicine in the world, Chinese (CTM) has a long history, which is treasure of combination and classical culture even more than 5000 years. For thousands years, CTM made great contributions to reproduction health people. It was an efficient therapeutic tool under guidance medical theory, its source generally natural products, but there are also small number it products after some processing methods. In fact, definition (CM) includes both new CM developed by modern technology. well known that chemical composition most very complex, for example, single herb may contain hundreds different chemicals, including active ingredients, side effects, toxic ingredients. Therefore, extraction process particularly crucial quality clinical efficacy products. this work, classification method proposed divide technologies into 21 kinds recent years analyze their status, advantages, disadvantages. Then put forward technical route based on ultra‐high‐pressure technology rapid else while removing harmful impurities making higher utilization useful exploration industry medicinal materials world.
Language: Английский
Citations
13
Molecules, Journal Year: 2024, Volume and Issue: 29(5), P. 967 - 967
Published: Feb. 22, 2024
Carotenoids, which are inherent pigments occurring in plants and microorganisms, manifest a diverse array of vivid hues. Owing to their multifarious health advantages, carotenoids have engendered substantial interest among scholars consumers alike. Presently, extensively employed the realms food, nutrition commodities, pharmaceuticals, cosmetics, rendering them an indispensable constituent our quotidian existence. Therefore, objective this review is present succinct methodical examination sources, constituents, factors influencing formation carotenoids. Particular attention will be given encapsulation strategies that maintain intrinsic characteristics, as growing desire for propelled by individuals’ escalating standards living. Moreover, applications natural multiple fields, including pharmaceutical, food feed, well discussed detail. Finally, article explores main challenges hindering future advancement carotenoids, aiming at facilitating effective integration into circular economy.
Language: Английский
Citations
13
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(14), P. 7603 - 7603
Published: July 11, 2024
This article presents a groundbreaking perspective on carotenoids, focusing their innovative applications and transformative potential in human health medicine. Research jointly delves deeper into the bioactivity bioavailability of revealing therapeutic uses technological advances that have to revolutionize medical treatments. We explore pioneering which carotenoids are used treat chronic diseases such as cancer, cardiovascular disease, age-related macular degeneration, offering novel protective mechanisms benefits. Our study also shows cutting-edge innovations carotenoid extraction bioavailability, including development supramolecular carriers advanced nanotechnology, dramatically improve absorption efficacy these compounds. These not only ensure consistent quality but tailor therapies each patient's needs, paving way for personalized By integrating latest scientific discoveries techniques, this research provides prospective clinical establishing new benchmark future studies field. findings underscore importance optimizing extraction, administration, bioactivity, methods develop more effective, targeted, treatments, thus visionary insight modern practices.
Language: Английский
Citations
12