Depression and Suicide in the “World’s Happiest Countries” DOI

Barry S. Fogel,

Xiaoling Jiang

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 380 - 429

Published: Jan. 30, 2025

Abstract The Nordic nations—Denmark, Finland, Iceland, Norway, and Sweden—and Switzerland are consistently among the world’s 10 “happiest countries.” Their residents enjoy excellent education healthcare, relatively high upward mobility, a small gender gap, natural beauty. However, their positive social determinants of health do not prevent depression or suicide. Compared with Western Europe overall, Finland Sweden have higher prevalence major depressive disorder. Suicide rates for both genders in Sweden, Switzerland; men Iceland; women Denmark Norway. Cultural differences help explain epidemiology. has historical trauma, tradition stoicism, widespread binge drinking. highly prevalent sexual harassment, leading to working women. Denmark’s hedonistic culture underlies lifestyle-related chronic medical conditions. Norway’s athletic, outdoor is antidepressant. French, Italian, German regions differ expressions depression.

Language: Английский

Therapeutic Strategies to Ameliorate Neuronal Damage in Epilepsy by Regulating Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation DOI Creative Commons
Sahithi Madireddy, Samskruthi Madireddy

Brain Sciences, Journal Year: 2023, Volume and Issue: 13(5), P. 784 - 784

Published: May 11, 2023

Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures that affects 50 million individuals globally. Because approximately one-third of patients with epilepsy do not respond to drug therapy, the development new therapeutic strategies against could be beneficial. Oxidative stress mitochondrial dysfunction are frequently observed in epilepsy. Additionally, neuroinflammation increasingly understood contribute pathogenesis Mitochondrial also recognized for its contributions neuronal excitability apoptosis, which can lead loss This review focuses on roles oxidative damage, dysfunction, NAPDH oxidase, blood–brain barrier, excitotoxicity, We therapies used treat prevent seizures, including anti-seizure medications, anti-epileptic drugs, anti-inflammatory therapies, antioxidant therapies. In addition, we use neuromodulation surgery treatment Finally, present role dietary nutritional management epilepsy, ketogenic diet intake vitamins, polyphenols, flavonoids. By reviewing available interventions research pathophysiology this points areas further manage

Language: Английский

Citations

43

LC-MS/MRM analysis of bioactive compounds from saffron (Crocus sativus L.) by-products: Optimization of phenolic compounds recovery using simplex centroid mixture design DOI

Chaimae Slimani,

Chaïmae Raïs, Farid Mansouri

et al.

Microchemical Journal, Journal Year: 2025, Volume and Issue: 209, P. 112714 - 112714

Published: Jan. 9, 2025

Language: Английский

Citations

1

Harnessing the power of nutritional antioxidants against adrenal hormone imbalance-associated oxidative stress DOI Creative Commons
Anil Patani, Deepak Balram, Virendra Kumar Yadav

et al.

Frontiers in Endocrinology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 30, 2023

Oxidative stress, resulting from dysregulation in the secretion of adrenal hormones, represents a major concern human health. The present review comprehensively examines various categories endocrine within glands, encompassing glucocorticoids, mineralocorticoids, and androgens. Additionally, comprehensive account hormone disorders, including insufficiency, Cushing’s syndrome, tumors, is presented, with particular emphasis on their intricate association oxidative stress. also delves into an examination nutritional antioxidants, namely vitamin C, E, carotenoids, selenium, zinc, polyphenols, coenzyme Q10, probiotics, elucidates role mitigating adverse effects stress arising imbalances levels. In conclusion, harnessing power antioxidants has potential to help caused by imbalance hormones. This could lead new research therapeutic interventions.

Language: Английский

Citations

17

Characterization of Azorean Plant Leaves for Sustainable Valorization and Future Advanced Applications in the Food, Cosmetic, and Pharmaceutical Industries DOI Creative Commons
Jorge Gomes Lopes Barros, Raquel Fernandes, Ana S. Abraão

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: 13(3), P. 325 - 325

Published: March 6, 2024

The historical use of plants as sources natural compounds has persisted over time. Increasing the intake bioactive substances shows significant potential for promoting overall well-being and health. This study delves into pigments, phenolic composition, profile, along with antioxidant properties, leaf extracts rich in bioactives from Azores region, contributing to sustainable primary food production. Analyses encompassed chlorophylls, carotenoids, total phenols, ortho-diphenols, flavonoids, well capacity assessment, polyphenolic profiling, quantification. Psidium guajava L. Smallanthus sonchifolius (Poepp.) H.Rob. exhibited elevated chlorophyll content, while Colocasia esculenta (L.) Schott displayed highest carotenoid levels. Annona cherimola Mill., Eriobotrya japonica (Thunb.) Lindl, demonstrated pronounced flavonoids. These findings align heightened capacity. HPLC–DAD (high-performance liquid chromatography diode-array detection) characterization unveiled hydroxycinnamic acids E. Ipomea batatas Lam. compared A. C. increased flavone content. Among quantified compounds, flavonols were ones that predominantly contribution these leaves. research highlights Azorean plants’ potential, fostering product development better

Language: Английский

Citations

6

An Overview on Atopic Dermatitis, Oxidative Stress, and Psychological Stress: Possible Role of Nutraceuticals as an Additional Therapeutic Strategy DOI Open Access
Clara Alessandrello, Serena Sanfilippo, Paola Lucia Minciullo

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(9), P. 5020 - 5020

Published: May 4, 2024

Atopic dermatitis (AD) is a chronic inflammatory skin condition with considerable impact on patients’ quality of life. Its etiology multifactorial and, among the predisposing factors, role played by oxidative stress. Pollution, recurrent infections, and psychological stress contribute to stress, amplifying production proinflammatory cytokines worsening barrier damage. There are various mechanisms involved in pathogenesis AD. Moreover, AD often appears be associated disorders such as alexithymia, depression, anxiety due severe itching related insomnia, well social distress isolation. The increasing incidence requires evaluation additional therapeutic approaches order reduce burden this condition. Our review aims evaluate some nutraceuticals treatment its comorbidities. combination natural compounds (flavonoids, alkaloids, terpenes, isothiocyanates) traditional treatments might useful improving effectiveness therapy, reducing inflammation preventing flare-ups, promoting corticosteroid sparing. In addition, these also appear have disorders, although underlying different from those already known for

Language: Английский

Citations

5

The Role of Dietary Antioxidants, Food Supplements and Functional Foods for Energy Enhancement in Healthcare Professionals DOI Creative Commons

Theodora Kalogerakou,

Μαρία Αντωνιάδου

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1508 - 1508

Published: Dec. 10, 2024

Healthcare professionals frequently experience significant work overload, which often leads to substantial physical and psychological stress. This stress is closely linked increased oxidative a corresponding decline in energy levels. scoping review investigates the potential impact of dietary antioxidants food supplements conjunction with diet controlling these negative effects. Through an analysis biochemical pathways involved metabolism, paper emphasizes effectiveness targeted interventions. Key antioxidants, such as vitamins C E, polyphenols, carotenoids, are evaluated for their ability counteract enhance Additionally, assesses various supplements, including omega-3 fatty acids, coenzyme Q10, ginseng, mechanisms action enhancement. Practical guidelines incorporating energy-boost strategies into routine healthcare provided, emphasizing importance modifications reducing improving overall well-being performance high-stress environments. The concludes by suggesting directions future research validate findings explore new interventions that may further support under overload.

Language: Английский

Citations

5

Fast food and anxiety symptoms of Chinese multi-ethnic adolescents: The moderating role of regulatory emotional self-efficacy DOI

Honglv Xu,

Ming Zhang, Chin-Hui Yang

et al.

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0

Recent progress in carotenoid encapsulation: Effects on storage stability, bioaccessibility and bioavailability for advanced innovative food applications DOI Creative Commons

Fani Sereti,

Maria Alexandri, Harris Papapostolou

et al.

Food Research International, Journal Year: 2025, Volume and Issue: 203, P. 115861 - 115861

Published: Jan. 30, 2025

Language: Английский

Citations

0

List of Abbreviations and Acronyms DOI

Barry S. Fogel,

Xiaoling Jiang

Published: Jan. 30, 2025

Language: Английский

Citations

0

Dimensions and Implications of Cultural Identity DOI

Barry S. Fogel,

Xiaoling Jiang

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 60 - 87

Published: Jan. 30, 2025

Abstract Cultural identity is intersectional: It includes not only race and nationality but also socioeconomic class, occupation, religion, gender, age/generation, life stage. Culture usefully characterized dimensionally. Hofstede identified dimensions of individualism/collectivism, power distance, uncertainty avoidance, gender role differentiation, short-term/long-term orientation, indulgence/restraint. Trust in individuals institutions, as well social capital—structural, relational, instrumental, cognitive—moderate the emotional effects stress adversity. clinicians enables effective treatment. The expression depression mediated by cultural communication styles, with their high-context/low-context, direct/indirect, self-enhancing/self-effacing, elaborate/understated. Word choices metaphors—which vary culture—help identify depression, indicate its severity, reveal suicide risk. Details critical for accurate diagnosis treatment can be “lost translation.”

Language: Английский

Citations

0