Effects of green tea consumption on oxidative stress and DNA repair in hospital staff exposed to low dose ionizing radiation DOI Creative Commons
Ping Wang,

Yuan Huo,

Xue Gao

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 21, 2023

Abstract Ionizing radiation (IR) is known to induce the formation of reactive oxygen species, which are linked chronic diseases. Tea most commonly consumed beverage worldwide. consumption was demonstrated have ameliorative effects in subjects with diseases, were explained by antioxidant and anti-inflammatory effects. This cross-sectional study evaluate potential benefits green tea on oxidative stress DNA repair induced occupational exposure IR. A cohort hospital workers exposed levels IR divided into two groups based their consumption. Peripheral blood cell count counted a automated Coulter Counter. Markers inflammatory detected commercial kit. gene expression RT-PCR.The no tea-consuming group presented significantly decreased plasma total content (TAC) superoxide dismutase (SOD) compared drinking group. In contrast, non-tea-drinking showed increased malondialdehyde (MDA) 8-hydroxy-2 deoxyguanosine (8-OHdG), indicating at tissue levels, respectively. The Group lower C-reactive protein TNF-α No Group. However, expressions genes (OGG1 XRCC1) not different between groups. conclusion, might be novel method for decreasing low

Language: Английский

Recent trends in the phytoremediation of radionuclide contamination of soil by cesium and strontium: Sources, mechanisms and methods: A comprehensive review DOI
Ayyoub Ammar, Asmae Nouira, Zineb El Mouridi

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 359, P. 142273 - 142273

Published: May 13, 2024

Language: Английский

Citations

15

Harmonizing Magnetic Mitohormetic Regenerative Strategies: Developmental Implications of a Calcium–Mitochondrial Axis Invoked by Magnetic Field Exposure DOI Creative Commons
Alfredo Franco‐Obregón

Bioengineering, Journal Year: 2023, Volume and Issue: 10(10), P. 1176 - 1176

Published: Oct. 10, 2023

Mitohormesis is a process whereby mitochondrial stress responses, mediated by reactive oxygen species (ROS), act cumulatively to either instill survival adaptations (low ROS levels) or produce cell damage (high levels). The mitohormetic nature of extremely low-frequency electromagnetic field (ELF-EMF) exposure thus makes it susceptible extraneous influences that also impinge on production and contribute the collective response. Consequently, magnetic stimulation paradigms are prone experimental variability depending diverse circumstances. failure, inability, control for these factors has contributed existing discrepancies between published reports in interpretations made from results generated therein. Confounding environmental include ambient fields, temperature, mechanical environment, conventional use aminoglycoside antibiotics. Biological type seeding density as well developmental, inflammatory, senescence statuses cells depend prior handling sample. Technological aspects directionality, uniformity, amplitude, duration exposure. All will exhibit manifestations at level culminate unified cellular response conjunction with Fortunately, many under experimenter. This review focus delineating areas requiring technical biological harmonization assist designing therapeutic strategies more clearly defined better predicted outcomes improve mechanistic interpretation data, rather than precise applications. explore underlying similarities other forms biophysical stimuli, such mutually induce elevations intracellular calcium prerequisite outcome. These stimuli commonly invoke activity transient receptor potential cation channel classes, TRPC1.

Language: Английский

Citations

11

Intravitreal melatonin for the prevention of radiation retinopathy: a step beyond bevacizumab DOI
Alper Kahvecioglu,

Ecem Yigit,

Nargiz Rustamova

et al.

International Journal of Radiation Biology, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 7

Published: Jan. 13, 2025

Purpose Intravitreal bevacizumab has been utilized to mitigate radiation retinopathy, yet the potential role of intravitreal melatonin for its prevention remains unexplored. This study aims evaluate and compare efficacy in preventing retinopathy an experimental animal model.

Language: Английский

Citations

0

Research advancements in machine learning-assisted design of reinforced composite radiation shields DOI
Ugochukwu C. Okonkwo, Christian Emeka Okafor, Shahnawaz Ahmad

et al.

Life Cycle Reliability and Safety Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Language: Английский

Citations

0

Potential effect of fruit and flower extracts of Arbutus unedo L. on Tetrahymena pyriformis exposed to a cobalt-60 source DOI Open Access

Fatine Belfekih,

Ahmed Moussaif, Mohammed El Mzibri

et al.

Journal of Experimental Biology and Agricultural Sciences, Journal Year: 2024, Volume and Issue: 12(2), P. 237 - 247

Published: May 15, 2024

Exposure of Tetrahymena pyriformis cultures to cobalt-60 for 72 h significantly impacted the cells' growth, appearance, and physiology. This study aims investigate protective effects Arbutus unedo L flowers fruit extracts on T. against gamma radiation. Initially, aqueous 50% ethanolic fruits were prepared, their cytotoxicity ciliate was evaluated. The irradiated ciliate's cellular viability morphological aspect improved when a non-toxic concentration 25 µg/mL added growth medium. addition restored glyceraldehyde-3-phosphate dehydrogenase succinate activities initial levels, similar non-irradiated cells. In addition, reduced oxidative stress markers, such as lipid peroxidation, decreased antioxidant defence enzymes, catalase, superoxide dismutase. may be attributed properties extracts. Results this revealed that flower exhibited better than extracts, with superior activity in in-vitro DPPH scavenging assay. These results suggest A. have potential exogenous radioprotective agents.

Language: Английский

Citations

0

Influence of Cu L-Histidinate Schiff Base Derivatives on Structural Features of Irradiated Rat’s DNA DOI
Nelli H. Karapetyan,

Samvel G. Haroutiunian,

Gayane V. Ananyan

et al.

Cell Biochemistry and Biophysics, Journal Year: 2024, Volume and Issue: 82(3), P. 2557 - 2565

Published: June 26, 2024

Language: Английский

Citations

0

Impact of Phytosanitary Irradiation on Polar Antioxidants in Peels of ‘Granny Smith’ Apples DOI Creative Commons

S. A. Alexander

Published: Aug. 1, 2024

The 'Granny Smith' apple (Malus domestica Borkh), known for its bright green peel and tart flavor, is a significant cultivar in the United States. Due to increasing limitations restrictions on chemical fumigants other treatments, ionizing radiation gaining popularity as phytosanitary treatment prevent spread of pests while preserving food quality. This study aimed evaluate effects gamma, e-beam, X-ray irradiation phenolic compounds, vitamin C content, total antioxidant capacity peels. results indicated that there were no changes content immediately following irradiation. However, after four months storage, gamma-treated peels showed decrease ascorbic acid an increase dehydroascorbic acid, e-beam treatments did not show changes. Phenolic initially decreased all increased with gamma showing most even though dose delivered was less than treatments. capacity, measured by ABTS DPPH assay, revealed irradiated samples storage. These findings suggest low rate associated might enhance specific properties impacting oxidation more profoundly

Language: Английский

Citations

0

Role of antioxidants in enhancing radioprotection: Insights from diagnostic radiology and radiotherapy studies DOI

S. Abhijith,

P. Aswathi

Karnataka Medical Journal, Journal Year: 2024, Volume and Issue: 0, P. 1 - 7

Published: Oct. 21, 2024

Introduction: With recent advancements, the usage of ionising radiation in diagnostic and therapeutic radiology is becoming increasingly important. Since smallest dose can also cause biological effects, most commonly indirect minimising this biggest challenge. The current review discussed efficacy antioxidants on neutralising free radicals formed as a result to minimise its effects DNA. Aim: aimed evaluate reducing caused by radiology. Materials Methodology: included articles published Scopus, PubMed Web Science databases were used. studies reported effectiveness antioxidant administration Results: evaluation methods used biochemical evaluation, histopathological gene expression, etc. Administration prior irradiation was effective effects. Melatonin found be multiple studies. Conclusion: Administering before effectively reduces Further human are necessary confirm same.

Language: Английский

Citations

0

Effects of green tea consumption on oxidative stress and DNA repair in hospital staff exposed to low dose ionizing radiation DOI Creative Commons
Ping Wang,

Yuan Huo,

Xue Gao

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 21, 2023

Abstract Ionizing radiation (IR) is known to induce the formation of reactive oxygen species, which are linked chronic diseases. Tea most commonly consumed beverage worldwide. consumption was demonstrated have ameliorative effects in subjects with diseases, were explained by antioxidant and anti-inflammatory effects. This cross-sectional study evaluate potential benefits green tea on oxidative stress DNA repair induced occupational exposure IR. A cohort hospital workers exposed levels IR divided into two groups based their consumption. Peripheral blood cell count counted a automated Coulter Counter. Markers inflammatory detected commercial kit. gene expression RT-PCR.The no tea-consuming group presented significantly decreased plasma total content (TAC) superoxide dismutase (SOD) compared drinking group. In contrast, non-tea-drinking showed increased malondialdehyde (MDA) 8-hydroxy-2 deoxyguanosine (8-OHdG), indicating at tissue levels, respectively. The Group lower C-reactive protein TNF-α No Group. However, expressions genes (OGG1 XRCC1) not different between groups. conclusion, might be novel method for decreasing low

Language: Английский

Citations

0