Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet

Journal of Translational Medicine, Journal Year: 2024, Volume and Issue: 22(1)

Published: March 21, 2024

Abstract Over the last decades, Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health undeniable taste that facilitated a widespread popularity. Researchers have investigated role of Mediterranean-type dietary patterns human all around world, reporting consistent findings concerning its benefits. However, what does truly define diet? The myriad scores synthesizes nutritional content diet, but variety aspects are generally unexplored when studying adherence this pattern. Among factors, main characteristics such as consumption fruit vegetables, olive oil, cereals should be accompanied by other underrated features, following: (i) specific reference whole-grain consumption; (ii) considering legumes, nuts, seeds, herbs spices often untested exploring diet; (iii) eggs dairy products common foods consumed in region (irrespectively modern demonization fat intake). Another feature includes (red) wine consumption, more general alcohol intake unmeasured, lacking specificity drinking occasion intensity (i.e., during meals). aspects, cooking methods rather simple yet extremely varied. Several related quality food was first investigated: locally produced, minimally processed, preserved with natural fermentation), strongly connected territory limited controlled impact environment. Dietary habits also associated lifestyle behaviors, sleeping patterns, social cultural values, favoring commensality frugality. In conclusion, it is reductive consider just pattern groups decontextualized from geographical background culture. While methodologies study demonstrated useful up date, holistic approach considered future studies aforementioned features values potentially applied globally through concept “Planeterranean” diet.

Language: Английский

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Mediterranean Diet and Quality of Life in Adults: A Systematic Review

Nutrients, Journal Year: 2025, Volume and Issue: 17(3), P. 577 - 577

Published: Feb. 5, 2025

Background/Objectives: With the increasing life expectancy and, as a result, aging of global population, there has been rise in prevalence chronic conditions, which can significantly impact individuals’ health-related quality life, multidimensional concept that comprises an individual’s physical, mental, and social wellbeing. While balanced, nutrient-dense diet, such Mediterranean is widely recognized for its role disease prevention, particularly reducing risk cardiovascular diseases certain cancers, potential benefits extend beyond these well-known effects, showing promise improving physical mental wellbeing, promoting life. Methods: A systematic search scientific literature electronic databases (Pubmed/Medline) was performed to identify potentially eligible studies reporting on relation between adherence diet published up December 2024. Results: total 28 were included this review, comprising 13 conducted among general population 15 involving various types patients. Overall, most showed significant association HRQoL, with results retrieved domains suggesting seems play relevant both people affected by conditions inflammatory basis. Conclusions: Adherence provides preventing managing commonly associated populations. Furthermore, it enhances overall health individuals, ultimately supporting more effective less invasive treatment approaches diseases.

Language: Английский

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Resveratrol and vascular health: evidence from clinical studies and mechanisms of actions related to its metabolites produced by gut microbiota

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: March 18, 2024

Cardiovascular diseases are among the leading causes of mortality worldwide, with dietary factors being main risk contributors. Diets rich in bioactive compounds, such as (poly)phenols, have been shown to potentially exert positive effects on vascular health. Among them, resveratrol has gained particular attention due its potential antioxidant and anti-inflammatory action. Nevertheless, results humans conflicting possibly interindividual different responses. The gut microbiota, a complex microbial community that inhabits gastrointestinal tract, called out responsible for modulating biological activities phenolic metabolites humans. present review aims summarize findings from clinical trials interventions endothelial outcomes mechanisms interesting role microbiota metabolism this molecule cardioprotective metabolites. randomized controlled show contrasting supplementation biomarkers without dose-dependent effect. In particular, studies which was integrated using food sources, i.e., red wine, reported significant although content was, average, much lower compared tablet supplementation, while other often extreme resulted null findings. experimental suggest exerts through modulation various antioxidant, anti-inflammatory, anti-hypertensive pathways, composition. Recent resveratrol-derived metabolites, piceatannol, demonstrated Moreover, itself improve composition toward an profile. Considering studies, future research exploring bidirectional link between well mediating effect cardiovascular health is warranted.

Language: Английский

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Anthocyanins for vascular health: plausible role of gut microbiota

International Journal of Food Sciences and Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 2

Published: March 10, 2025

Language: Английский

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Αnti-prion effects of anthocyanins

Redox Biology, Journal Year: 2024, Volume and Issue: 72, P. 103133 - 103133

Published: March 28, 2024

Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), are protein-based neurodegenerative disorders (NDs) affecting humans and animals. They characterized by the conformational conversion of normal cellular prion protein, PrPC, into pathogenic isoform, PrPSc. diseases invariably fatal despite ongoing research, no effective prophylactic or therapeutic avenues currently available. Anthocyanins (ACNs) unique flavonoid compounds interest in their use potential neuroprotective and/or agents against NDs, has increased significantly recent years. Therefore, we investigated anti-oxidant anti-prion effects Oenin Myrtillin, two most common anthocyanins, using accepted field overexpressing PrPSc vitro model a cell free protein aggregation model. Our results, indicate both anthocyanins strong compounds, upregulating expression genes involved response, reducing levels Reactive Oxygen Species (ROS), produced due to infection, through activation Keap1-Nrf2 pathway. Importantly, they showcased remarkable potential, not only caused clearance aggregates, but completely inhibited formation fibrils Cerebrospinal Fluid (CSF) patients with Creutzfeldt–Jakob disease (CJD). Myrtillin possess pleiotropic effects, suggesting promising preventive possibly spectrum proteinopathies.

Language: Английский

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Influence of time-temperature in the antioxidant activity, anthocyanin and polyphenols profile, and color of Ardisia compressa K. extracts, with the addition of sucrose or citric acid

Food Chemistry, Journal Year: 2023, Volume and Issue: 440, P. 138181 - 138181

Published: Dec. 9, 2023

Language: Английский

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Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approaches in Non-Communicable Diseases III

Antioxidants, Journal Year: 2024, Volume and Issue: 13(11), P. 1404 - 1404

Published: Nov. 16, 2024

Non-communicable diseases (NCDs), including cardiovascular diseases, diabetes, and neurodegenerative disorders, pose a significant global health challenge [...].

Language: Английский

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Potential of Anthocyanin-rich Products to Prevent and Improve Endothelial Function and Senescence: Focus on Anthocyanins

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 4, 2024

Endothelial dysfunction is a pivotal early event in the development of major cardiovascular diseases including hypertension, atherosclerosis, diabetes, and aging. The alteration endothelial function often triggered by an imbalance between formation vasoprotective factors, nitric oxide (NO) endothelium-dependent hyperpolarization (EDH), vasocontracting such as arachidonic acid-derived mediators generated cyclooxygenases, increased level oxidative stress. Recently, senescence was reported to be trigger dysfunction. Preclinical studies indicate that polyphenol-rich food, anthocyanin-rich products, can activate pathways promoting factors prevent induction cells isolated blood vessels. Similarly, intake products has been associated with prevention and/or improvement several experimental models diseases, physiological Moreover, clinical data improve vascular health humans diseases. present review will discuss both evidence indicating foods natural especially promote health, well underlying mechanisms.

Language: Английский

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The association between comprehensive dietary antioxidant index and erectile dysfunction in adult men: a cross-sectional study from the 2001-2004 U.S. National Health and Nutrition Examination Survey

Sexual Medicine, Journal Year: 2024, Volume and Issue: 12(6)

Published: Dec. 1, 2024

Language: Английский

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Purple Tea (Camellia sinensis var. assamica) Leaves and Obesity Management: A Review of 1,2-Di-Galloyl-4,6-Hexahydroxydiphenoyl-β-D-Glucose’s (GHG) Potential Health Benefits, and Future Prospects

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 3, 2024

Purple tea (

Language: Английский

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