Fullerenol C60(OH)40 Nanoparticles and Ectoine Protect Human Nasal Epithelial Cells Against the Cytokine Storm After Addition of the Full-Length Spike Protein from SARS-CoV-2 DOI Creative Commons
Malwina Sosnowska, Mateusz Wierzbicki, Barbara Nasiłowska

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 12221 - 12255

Published: Nov. 1, 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the nasal cavity, penetrates epithelial cells through interaction of its spike protein with host cell receptor angiotensin-converting enzyme (ACE2) and then triggers a cytokine storm. We aimed to assess biocompatibility fullerenol nanoparticles C

Language: Английский

Postbiotics as a health-promoting technique: A review article on scientific and commercial interest DOI

Amira M. Heniedy,

Dina M. Mahdy,

Wesam Ibrahim Abo- Elenien

et al.

Process Biochemistry, Journal Year: 2024, Volume and Issue: 144, P. 6 - 19

Published: May 14, 2024

Language: Английский

Citations

4
Probiotic, Postbiotic, and Paraprobiotic Effects of Lactobacillus rhamnosus as a Modulator of Obesity-Associated Factors DOI Creative Commons
Gabriela López-Almada, María Esther Mejía-León, Norma Julieta Salazar‐López

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(22), P. 3529 - 3529

Published: Nov. 5, 2024

Obesity is a pandemic currently affecting the world's population that decreases quality of life and promotes development chronic non-communicable diseases.

Language: Английский

Citations

4
Study on the In Vitro and In Vivo Antioxidant Activity and Potential Mechanism of Polygonum viviparum L. DOI Creative Commons
Zhen Yang,

Jingyuan Man,

Haoyu Liu

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(1), P. 41 - 41

Published: Jan. 1, 2025

Oxidative stress refers to the phenomenon in which redox balance of body is disrupted response stimuli, leading an excessive accumulation reactive oxygen species vivo, can lead a variety diseases. In contrast artificial antioxidants, whose safety controversial, natural are widely available, pharmacologically active, and have little toxic side effects, expected be candidates for treatment oxidative stress-related Polygonum viviparum L. (PV) herbal medicine with antioxidant properties used as traditional Tibetan Plateau region. However, there few studies that focused on its activity mechanism action vitro vivo. Therefore, present study firstly demonstrated PV could exert good effects by scavenging DPPH radicals inhibiting production hydroxyl through experiments. Secondly, was proven attenuate weight gain thymus development establishing Senna leaf-induced diarrhea model rats, well increase enzymes content non-enzymatic antioxidants intestinal tract enhance rats’ own defenses, mitigate damage caused diarrhea. Subsequently, application cellular evidenced play protective role against overaccumulation ROS macrophages. Furthermore, candidate targets were analyzed screened using comprehensive network pharmacology method, their expression then examined at mRNA level protein level. Our results suggest may protect H2O2-induced macrophages activating BCL2L1 ESR1, JAK2/STAT3, MMP2. These findings open new perspectives prospect developing it novel drug.

Language: Английский

Citations

0
Postbiotic Potential of Newly Isolated Riboflavin-Overproducing Lactiplantibacillus plantarum Strains DOI Creative Commons
Angela Scauro, Maria Teresa Rocchetti, Mario Soccio

et al.

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: April 23, 2025

Language: Английский

Citations

0
Use of Probiotic/ Postbiotic along with Starter Bacteria for Enhancing Fermentation Processes –A Review DOI Open Access

Moghadam SK

Food Science & Nutrition Technology, Journal Year: 2024, Volume and Issue: 9(2), P. 1 - 9

Published: April 2, 2024

Postbiotics or/ and inactivated probiotics recently have driven attention it seems they can overcome the problems of probiotics. This paper explores a comparison between (postbiotics) containing starter bacteria in fermented products. The study focused on potential synergies benefits incorporating probiotic cells into fermentation process especially to enhance viability cultures, physicochemical nutritional properties, elevate overall product quality. In this context, substitution with postbiotics is being considered.

Language: Английский

Citations

1
Acute Infectious Diarrhea DOI
Marco Poeta, Margherita Del Bene, Andrea Lo Vecchio

et al.

Advances in experimental medicine and biology, Journal Year: 2024, Volume and Issue: unknown, P. 143 - 156

Published: Jan. 1, 2024

Language: Английский

Citations

1
Fullerenol C60(OH)40 Nanoparticles and Ectoine Protect Human Nasal Epithelial Cells Against the Cytokine Storm After Addition of the Full-Length Spike Protein from SARS-CoV-2 DOI Creative Commons
Malwina Sosnowska, Mateusz Wierzbicki, Barbara Nasiłowska

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 12221 - 12255

Published: Nov. 1, 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the nasal cavity, penetrates epithelial cells through interaction of its spike protein with host cell receptor angiotensin-converting enzyme (ACE2) and then triggers a cytokine storm. We aimed to assess biocompatibility fullerenol nanoparticles C

Language: Английский

Citations

0