Sperm DNA Fragmentation: Unraveling Its Imperative Impact on Male Infertility Based on Recent Evidence

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(18), P. 10167 - 10167

Published: Sept. 22, 2024

Male factors may be present in up to 50–70% of infertile couples and the prevalence male infertility accounts for 20–30% cases. Understanding mechanisms causes behind remains a challenge, but new diagnostic tools such as DNA fragmentation might aid cases where routine semen analysis is insufficient. fragmentation, which refers damages or breaks genetic material spermatozoa, considered one main due impaired functional capability sperm. The aim narrative review investigate enlighten potential correlation between parameters seminal profile reproductive outcomes. Comprehensive research PubMed/Medline Scopus databases was conducted 28 studies were included review. Fourteen provided data regarding impact showed significantly lower sperm count, concentration, motility, abnormal morphology with an increased index (DFI). Similarly, 15 DFI on Two higher aneuploidy rates values, seven pregnancy live birth values. Ultimately, this highlight, collectively, importance measuring assessment infertility. Further are needed explore effectiveness interventions aiming reduce levels.

Language: Английский

The assessment of oxidative stress in human semen. Chaos and confusion in pursuit of diagnostic precision

Reproductive BioMedicine Online, Journal Year: 2024, Volume and Issue: 50(2), P. 104488 - 104488

Published: Oct. 16, 2024

Language: Английский

Correction: Ogawa et al. Micronutrient Antioxidants for Men (Menevit®) Improve Sperm Function by Reducing Oxidative Stress, Resulting in Improved Assisted Reproductive Technology Outcomes. Antioxidants 2024, 13, 635

Antioxidants, Journal Year: 2024, Volume and Issue: 13(12), P. 1569 - 1569

Published: Dec. 20, 2024

In the originally published article [...]

Language: Английский