Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health

Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

Language: Английский

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Can We Modulate Our Second Brain and Its Metabolites to Change Our Mood? A Systematic Review on Efficacy, Mechanisms, and Future Directions of “Psychobiotics”

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(5), P. 1972 - 1972

Published: Feb. 25, 2025

Psychobiotics, live microorganisms that provide mental health by interacting with the gut microbiota, are emerging as a promising therapeutic option for psychiatric and neurodevelopmental disorders. Their effectiveness in addressing conditions such depression, anxiety, insomnia, stress, autism spectrum disorder (ASD), eating disorders were examined through comprehensive analysis of existing studies up to first half 2024, based on data from reliable electronic databases. We found psychobiotics can significantly reduce symptoms various influencing neurotransmitter levels, regulating hypothalamic-pituitary-adrenal (HPA) axis, improving barrier function short-chain fatty acids (SCFAs) other metabolites. However, several limitations identified, including inconsistent study methodologies, small sample sizes, lack long-term safety. Addressing these rigorous research is essential establishing standardized protocols fully confirming potential psychobiotics. In conclusion, show great promise complementary treatments conditions, but continued necessary refine their application integrate them into clinical practice effectively.

Language: Английский

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Future Trends and Conclusion on Bioactive Phytochemicals in By-products from Leaf, Stem, Root, and Tuber Vegetables

Published: Jan. 1, 2025

Language: Английский

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