Antioxidant Activity of Polyphenolic Plant Extracts

Antioxidants, Journal Year: 2019, Volume and Issue: 9(1), P. 19 - 19

Published: Dec. 24, 2019

Plant polyphenols are secondary metabolites characterized by one or more hydroxyl groups binding to aromatic rings [...].

Language: Английский

---

Kombucha: A review of substrates, regulations, composition, and biological properties

Journal of Food Science, Journal Year: 2022, Volume and Issue: 87(2), P. 503 - 527

Published: Jan. 14, 2022

Abstract Kombucha has been gaining prominence around the world and becoming popular due to its good health benefits. This beverage is historically obtained by tea fermentation of Camellia sinensis a biofilm cellulose containing symbiotic culture bacteria yeast (SCOBY). The other substrates added C. have also reported help kombucha production. type as well amount sugar substrate, which origin SCOBY, in addition time temperature influence content organic acids, vitamins, total phenolics, alcoholic kombucha. route involved metabolite biotransformation identified so far microorganisms process need be further studied. Some nutritional properties benefits related already reported. Antioxidant antimicrobial activities antidiabetic anticarcinogenic effects are some beneficial attributed Nevertheless, scientific literature needs clinical studies evaluate these human beings. toxic associated with consumption still unclear, but possibility adverse reactions occurring, contraindicated infants pregnant women, children under 4‐years‐old, patients kidney failure, HIV. regulations place for address number criteria, mainly pH alcohol content, order guarantee quality safety ensure transparency information consumers.

Language: Английский

---

Investigation of the Influence of Different Camellia sinensis Teas on Kombucha Fermentation and Development of Flavored Kombucha with Brazilian Fruits

Beverages, Journal Year: 2025, Volume and Issue: 11(1), P. 13 - 13

Published: Jan. 14, 2025

Teas derived from Camellia sinensis are traditionally used in kombucha fermentation, a process which bacteria and yeasts play key roles. This study aimed to evaluate the effects of green, black, white teas, as well their combinations, on physicochemical properties, antioxidant capacity, total phenolic compound content kombucha. In addition, production flavored with fruits. Statistical analysis simplex centroid mixture design indicated that green tea promoted positive increase activities against ABTS DPPH free radicals, being observed at 5868.46 µmol/mL, 705.40 380.77 mg GAE/100 mL prepared using this individually. Then, six beverages were tea, grape, caja, cashew apple, genipap, passion fruit, tamarind. The profile revealed presence twenty-six compounds, including twenty-five phenolics one caffeine derivative. Among beverages, tamarind-flavored stood out, exhibiting highest flavonoid (156.77 EQ/g), highlights influence tamarind bioactive properties beverages. These results provide valuable insights optimize explore potential beneficial non-alcoholic

Language: Английский

---

Recent advances in research on vine tea, a potential and functional herbal tea with dihydromyricetin and myricetin as major bioactive compounds

Journal of Pharmaceutical Analysis, Journal Year: 2020, Volume and Issue: 11(5), P. 555 - 563

Published: Oct. 14, 2020

Vine tea has been used as an herbal by several ethnic minorities for hundreds of years in China. Flavonoids, a kind indispensable component variety nutraceutical, pharmaceutical and cosmetic applications, are identified to be the major metabolites bioactive ingredients vine tea. Interestingly, exhibits wide range significant bioactivities including anti-oxidant, anti-inflammatory, anti-tumor, antidiabetic, neuroprotective other activities, but no toxicity. These bioactivities, some extent, enrich understanding about role disease prevention therapy. The health benefits tea, particularly dihydromyricetin myricetin, widely investigated. However, there is currently comprehensive review available on Therefore, this report summarizes most recent studies investigating constituents, pharmacological effects possible mechanisms which will provide better preclinical assessment novel application

Language: Английский

---

DNA barcoding: a modern age tool for detection of adulteration in food

Critical Reviews in Biotechnology, Journal Year: 2021, Volume and Issue: 41(5), P. 767 - 791

Published: Feb. 2, 2021

Globalization of the food trade requires precise and exact information about origin, methods production, transformation technologies, authentication, traceability foodstuffs. New challenges in supply chains such as deliberate fraudulent substitution, tampering or mislabeling its ingredients packaging incapacitates market eventually national economy. Currently, no proper standards have been established for authentication most materials. However, order to control fraud, various robust cost-effective technologies employed, like a spectrophotometer, GC-MS, HPLC, DNA barcoding. Among these techniques, barcoding is biotechnology advantage with principle using 400–800 bp long standardized unique sequences mitochondrial (e.g. COI) plastidial rbcL) nuclear origin ITS) analyze classify commodities. This review covers several traded commodities legumes, seafood, oils, herbal products, spices, fruits, cereals, meat, their barcodes which are critically analyzed detect adulteration fraud. global initiative it being accepted standard/marker species identification authentication. The research laboratories industries should collaborate realize potential setting quality assurance, control, safety different products.

Language: Английский

---

Anti-oxidant potential of plants and probiotic spp. in alleviating oxidative stress induced by H2O2

Biomedicine & Pharmacotherapy, Journal Year: 2023, Volume and Issue: 165, P. 115022 - 115022

Published: June 17, 2023

Cells produce reactive oxygen species (ROS) as a metabolic by-product. ROS molecules trigger oxidative stress feedback response that significantly initiates biological processes such autophagy, apoptosis, and necrosis. Furthermore, extensive research has revealed hydrogen peroxide (H2O2) is an important entity plays crucial role in several physiological processes, including cell differentiation, signalling, apoptosis. However, excessive production of H2O2 been shown to disrupt biomolecules organelles, leading inflammatory contributing the development health complications collagen deposition, aging, liver fibrosis, sepsis, ulcerative colitis, etc. Extracts different plant species, phytochemicals, Lactobacillus sp (probiotic) have reported for their anti-oxidant potential. In this view, researchers gained significant interest exploring potential plants spp., sp. strains exhibit properties benefits. Thus, current review focuses on comprehending information related formation H2O2, factors influencing it, pathophysiology imposed human health. Moreover, also discussed extract plants, fermented products curbing H2O2‑induced both in-vitro in-vivo models via boosting anti-oxidative activity, inhibiting enzyme release downregulation cytochrome c, cleaved caspases-3, - 8, 9 expression. particular, knowledge will assist R&D sections biopharmaceutical food industries developing herbal medicine probiotics-based or derived can effectively alleviate issues induced by generation.

Language: Английский

---

Kombucha Beverages Produced from Fruits, Vegetables, and Plants: A Review on Their Pharmacological Activities and Health Benefits

Foods, Journal Year: 2023, Volume and Issue: 12(9), P. 1818 - 1818

Published: April 27, 2023

Kombucha is a traditional health beverage produced by fermenting sweetened tea with symbiotic culture of bacteria and yeasts. Consumption kombucha beverages has been growing there commercially available worldwide as one the most famous low-alcohol beverages. have claimed to beneficial effects on human because they contain variety bioactive compounds that possess various functional properties. At present, several kinds raw material (e.g., milk, fruit, vegetables, herbs) fermented consortium consumed Although studies written regarding biological activities materials, however little information characterization their components well from many mixtures. Several pharmacological were reviewed in scientific literature, describing potential implications for health. In addition, adverse toxicity consumption also reviewed. this study, we focused main latest including antioxidant, anti-inflammatory, immunomodulatory, antimicrobial, anticancer, antidiabetic, antihypertensive, antihyperlipidemic vitro vivo studies.

Language: Английский

---

Size-dependent antibacterial efficacy of silver nanoparticles from a green synthesis method: Effects of extract quantity and origin

Journal of the Taiwan Institute of Chemical Engineers, Journal Year: 2024, Volume and Issue: 161, P. 105511 - 105511

Published: April 21, 2024

Language: Английский

---

Anti-inflammatory and antioxidant properties of Camellia sinensis L. extract as a potential therapeutic for atopic dermatitis through NF-κB pathway inhibition

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 18, 2025

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by immune dysregulation and excessive cytokine production. This study aimed to explore the potential of Camellia sinensis L. water extract (CSE) as treatment for AD impact CSE on responses in keratinocytes, particularly concerning production cytokines modulation signaling pathways relevant pathogenesis. was obtained via hot extraction from Ultra-high-performance liquid chromatography (UPLC) analyzed catechin caffeine content. Cell viability assessed with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), polyphenol flavonoid content were determined. 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay measured antioxidant activity. Enzyme-Linked Immunosorbent Assay (ELISA), western blotting, Immunofluorescence (IF) assays examined cytokines, pathways, protein localization, respectively. Molecular docking compound binding inflammation-related proteins. UPLC identified six components including epigallocatechin (EGC) epicatechin (EC), (CF), (C), gallate (EGCG), (ECG). demonstrated significant reduction interleukin (IL)-2 IL-6 TNF-α/IFN-γ activated keratinocytes. Treatment inhibited mitogen-activated kinase (MAPK) pathway, which resulted decreased phosphorylation p38, Jun N-terminal (JNK), extracellular signal-regulated (ERK). Exposure TNF-α/IFN-γ- stimulated human keratinocytes (HaCaT) cells 200 µg/mL dependent inhibition p65 signal transducer activator transcription 1 (STAT-1) translocation cytosol nucleus, confirmed through immunofluorescence staining. simulations provided insights into underlying mechanisms action, supported its therapeutic agent AD. might be candidate efficacy conditions like Thus, based this evidence, authors suggest that should studied further anti-inflammatory activities topical application

Language: Английский

---

Transcriptome and Metabolic Profiling Unveiled Roles of Peroxidases in Theaflavin Production in Black Tea Processing and Determination of Tea Processing Suitability

Journal of Agricultural and Food Chemistry, Journal Year: 2020, Volume and Issue: 68(11), P. 3528 - 3538

Published: March 4, 2020

Theaflavins (TFs) are generated by endogenous polyphenol oxidase (PPO)- and peroxidase (POD)-catalyzed catechins oxidation during black tea processing, which needs to be well-controlled obtain a proper TFs/thearubigins (TRs) ratio for better quality. Not all leaves from any plant cultivars or varieties suitable making high-quality teas, regardless of the processing techniques. The mechanisms underlying TFs formation main factors determining leaf suitability not fully understood. We here integrated transcriptome metabolite profiling unveil how enzymes metabolites in changed processing. information enabled us identify several PPO POD genes potentially involved TF production. characterized gene, whose recombinant enzyme showed creation activity. capacity POD-catalyzed production could used as molecular marker breeding

Language: Английский

---