Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: March 12, 2025
Abstract
Biofilm
formation
is
responsible
for
persistent
diseases
related
to
chronic
infections.
Mostly
it
triggered
by
many
bacteria,
mainly
Pseudomonas
aeruginosa
(
P.
).
In
this
study,
plants
that
have
been
used
traditionally
in
skin
infections
Viz;
Liquorice,
Carrot,
Red
Cabbage,
Beetroot,
Turmeric,
Neem,
and
French
Lavender
were
selected
evaluate
their
antibiofilm
activity
against
.
The
microtiter
plate
assay
was
as
well
ability
reduce
the
of
To
investigate
phytocompounds
bioactivity
superior
extract
explore
potential
interactions
between
its
bioactive
components
one
quorum-sensing
(QS)
regulatory
proteins
involved
biofilm
formation,
liquid
chromatography-mass
spectrometric
(LC-MS)
molecular
docking
studies
done.
study
showed
all
tested
plant
extracts
could
significantly
p
-value
<
0.05)
biofilm.
methanol
Lavandula
dentata
L.
)
leaves
at
0.625
mg/mL.
conclusion,
revealed
presence
phenolic
acids,
flavonoids,
glycosides
also,
anti-
reported
herein
first
time
be
a
good
source
leads
medicine.
Journal of King Saud University - Science,
Journal Year:
2023,
Volume and Issue:
35(3), P. 102558 - 102558
Published: Jan. 11, 2023
Endophytic
fungi
are
widely
known
to
reside
in
plant
tissues
causing
no
harm
host
plants
or
even
noticeable
change.
They
may
colonize
for
a
part
of
their
life
cycle
complete
the
entire
since
provide
variety
novel
metabolites.
Despite
being
close
relationship
with
medicinal
plants,
diversity
and
metabolic
spectrum
endophytic
have
not
been
researched
well.
Their
ecological
niche
as
symbionts
make
them
attractive
targets
search
biochemicals.
We
aimed
isolate,
purify,
characterize
fungal
population
cultivated
Riyadh,
Saudi
Arabia.
The
goal
was
achieved
through
morphological
identification
internal
transcribed
spacer
(ITS)
regions
rRNA
analyses
determine
phylogeny
diversity.
Three
aromatic
Jasminum
sambac,
Camellia
sinensis,
Ocimum
basilicum
collected
from
Riyadh
region,
Arabia
were
investigated.
In
total,
84
isolates
purified
they
grouped
into
20
operational
taxonomic
units
(OTUs)
per
sequences
ITS
rRNA.
Twenty
species
12
genera
i.e.
Neopestalotiopsis,
Trichoderma,
Fusarium,
Colletotrichum,
Myrothecium,
Chaetomium,
Alternaria,
Phoma,
Curvularia,
Cladosporium,
Neodidymelliopsis,
Aspergillus
all
belonged
Ascomycota
phylum.
J.
sambac
found
dominant
among
other
had
relative
frequency
27%.
C.
sinensis
next
18.7%
frequency.
prominently
recorded
leaf
organs
over
stem
roots
while
exhibited
lowest
Isolates
also
produced
indole-3-acetic
acid
(IAA),
1-aminocyclopropane-1-carboxylic
(ACC)
deaminase
enzyme,
siderophores
variable
magnitudes
that
could
be
assigned
wide
range
variations
species.
Conclusively,
O.
good
source
certain
growth-promoting
traits.
Overall,
Alternaria
most
predominant
genus
terms
colonization
rate.
Further
deternminations
required
screen
beneficial
compounds
released
by
these
fungi.
Plants,
Journal Year:
2024,
Volume and Issue:
13(2), P. 236 - 236
Published: Jan. 15, 2024
Tobacco
(Nicotiana
tabacum
L.)
is
a
major
industrial
crop
that
has
being
cultivated
for
centuries
the
manufacturing
of
cigarettes,
cigars,
and
other
smoking
products.
Due
to
its
negative
effects
on
both
human
health
environment,
European
Union
adopted
strict
policies
aspire
reduce
consumption
tobacco.
Herbal
cigarettes
are
alternative
products
often
advertised
as
healthier
than
conventional
tobacco
especially
popular
in
Asian
markets.
Even
though
available
literature
suggests
they
equally
detrimental
health,
introduction
tobacco-alternative
crops
(TACs)
industry
could
smoothen
abandonment
tobacco,
eventually
altogether,
EU.
The
aim
present
systematic
review
was
compile
list
possible
TACs
be
incorporated
industry,
highlight
their
strengths
weaknesses.
most
dominant
(and
existing
market
products)
were
calendula
(Calendula
officinalis
L.),
mullein
(Verbascum
thapsus
ginseng
(Panax
C.A.Mey.),
tea
(Camellia
sinensis
(L.)
Kuntze),
chamomile
(Matricaria
chamomilla
mentha
(Mentha
spp.).
these
promising,
further
research
required
incorporation
industry.
Metabolic Brain Disease,
Journal Year:
2024,
Volume and Issue:
39(5), P. 953 - 966
Published: June 13, 2024
Abstract
Monosodium
glutamate
(MSG)
is
the
sodium
compound
derived
from
glutamic
acid.
Excessive
daily
ingestion
of
MSG
leads
to
elevated
amounts
acid
in
bloodstream,
which
can
be
detrimental
brain
structures.
Camellia
sinensis,
often
known
as
green
tea
(GT),
a
rich
source
essential
hexogen
antioxidants
that
are
necessary
for
body.
Thirty-two
adult
male
albino
rats
were
divided
into
four
groups
(
n
=
8).
Group
1
served
control
-ve
group.
2
was
given
GT
(1.5
ml/rat/day).
3
(600
mg/kg/day).
4
mg/kg/day)
and
All
treatments
orally
28
days.
administration
resulted
significant
neurotoxicity
revealed
by
reduction
serum
concentration
glutathione
peroxidase
(GPx)
nitric
oxide
(NO),
elevation
total
antioxidant
capacity
(TAC)
accompanied
levels
monoamines
(dopamine,
serotonin,
norepinephrine)
histological
changes
hippocampus
area
CA1,
dentate
gyrus,
cerebellar
cortex
positive
immunohistochemical
staining
glial
fibrillary
acidic
proteins
(GFAP)
calretinin.
Administration
with
counteracted
MSG-mediated
oxidative
stress
significantly
increasing
concentrations
GP
X
NO
decreasing
TAC.
Furthermore,
increased
norepinephrine).
Moreover,
it
ameliorated
changes,
GFAP,
calretinin
immunostaining
tissues.
It
envisaged
will
serve
viable
protective
choice
inclusion
treatment
procedure.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: March 12, 2025
Abstract
Biofilm
formation
is
responsible
for
persistent
diseases
related
to
chronic
infections.
Mostly
it
triggered
by
many
bacteria,
mainly
Pseudomonas
aeruginosa
(
P.
).
In
this
study,
plants
that
have
been
used
traditionally
in
skin
infections
Viz;
Liquorice,
Carrot,
Red
Cabbage,
Beetroot,
Turmeric,
Neem,
and
French
Lavender
were
selected
evaluate
their
antibiofilm
activity
against
.
The
microtiter
plate
assay
was
as
well
ability
reduce
the
of
To
investigate
phytocompounds
bioactivity
superior
extract
explore
potential
interactions
between
its
bioactive
components
one
quorum-sensing
(QS)
regulatory
proteins
involved
biofilm
formation,
liquid
chromatography-mass
spectrometric
(LC-MS)
molecular
docking
studies
done.
study
showed
all
tested
plant
extracts
could
significantly
p
-value
<
0.05)
biofilm.
methanol
Lavandula
dentata
L.
)
leaves
at
0.625
mg/mL.
conclusion,
revealed
presence
phenolic
acids,
flavonoids,
glycosides
also,
anti-
reported
herein
first
time
be
a
good
source
leads
medicine.